Results 11 to 20 of about 296,841 (265)

Experimental Investigations on the Structure of Yeast Mitochondrial Pyruvate Carriers

open access: yesMembranes, 2022
Mitochondrial pyruvate carrier (MPC) transports pyruvate from the cytoplasm into the mitochondrial matrix to participate in the tricarboxylic acid (TCA) cycle, which further generates the energy for the physiological activities of cells.
Ling Li   +4 more
doaj   +1 more source

ME2 Promotes Hepatocellular Carcinoma Cell Migration through Pyruvate

open access: yesMetabolites, 2023
Cancer metastasis is still a major challenge in clinical cancer treatment. The migration and invasion of cancer cells into surrounding tissues and blood vessels is the primary step in cancer metastasis.
Yanting Yang   +5 more
doaj   +1 more source

PRE-PERFUSION LACTATE LEVEL AND LACTATE-PYRUVATE RATIO AS A PROGNOSTIC CRITERION OF DEVELOPMENT OF POST-PERFUSION CARDIAC FAILURE DURING THE MYOCARDIAL REVASCULIZATION SURGERY WITH THE USE OF CARDIOPULMONARY BYPASS

open access: yesВестник анестезиологии и реаниматологии, 2018
Goal of the study: to detect the correlation between lactate and pyruvate levels and their ratio (LPR) during ischemia/reperfusion with the post-operative increase of troponin I as a marker of myocardial lesion. Materials and methods.
Yu. S. Polushin   +5 more
doaj   +1 more source

Malate-Aspartate Shuttle Plays an Important Role in LPS-Induced Neuroinflammation of Mice Due to its Effect on STAT3 Phosphorylation

open access: yesFrontiers in Molecular Biosciences, 2021
Neuroinflammation is a key pathological factor in numerous neurological disorders. Cumulating evidence has indicated critical roles of NAD+/NADH metabolism in multiple major diseases, while the role of malate-aspartate shuttle (MAS) - a major NADH ...
Cuiyan Zhou   +5 more
doaj   +1 more source

Fibroblasts as the subject of proliferative activity research in vitro

open access: yesНаука и инновации в медицине, 2020
This review presents the data devoted to anatomical and functional diversity of fibroblasts, peculiarities of metabolic processes and energy exchange in these cells.
Valeriya I. Kuzmicheva   +5 more
doaj   +1 more source

Effects of Sodium Pyruvate on Vanadyl Sulphate-Induced Reactive Species Generation and Mitochondrial Destabilisation in CHO-K1 Cells

open access: yesAntioxidants, 2022
Vanadium is ranked as one of the world’s critical metals considered important for economic growth with wide use in the steel industry. However, its production, applications, and emissions related to the combustion of vanadium-containing fuels are known ...
Iwona Zwolak, Ewa Wnuk
doaj   +1 more source

Role of sodium pyruvate in maintaining the survival and cytotoxicity of Staphylococcus aureus under high glucose conditions

open access: yesFrontiers in Microbiology, 2023
Glucose is a crucial carbon source for the growth of Staphylococcus aureus, but an excess of glucose is detrimental and even leads to cell death. Pyruvate, the central metabolite of glycolysis, has been shown to have anti-inflammatory and antioxidant ...
Ti Chen, Huan Xu, Xiaoyan Yao, Zhen Luo
doaj   +1 more source

Pyruvate: A key Nutrient in Hypersaline Environments?

open access: yesMicroorganisms, 2015
Some of the most commonly occurring but difficult to isolate halophilic prokaryotes, Archaea as well as Bacteria, require or prefer pyruvate as carbon and energy source.
Aharon Oren
doaj   +1 more source

Shift of the reaction equilibrium at high pressure in the continuous synthesis of neuraminic acid

open access: yesBeilstein Journal of Organic Chemistry, 2022
The importance of a compound that helps fight against influenza is, in times of a pandemic, self-evident. In order to produce these compounds in vast quantities, many researchers consider continuous flow reactors in chemical industry as next stepping ...
Jannis A. Reich   +5 more
doaj   +1 more source

The relationships between transketolase, yeast pyruvate decarboxylase and pyruvate dehydrogenase of the pyruvate dehydrogenase complex [PDF]

open access: yesFEBS Letters, 1993
The amino acid sequences of four thiamine pyrophosphate‐requiring enzymes were aligned with the published amino acid sequence of the transketolase of Hansenula polymorpha. Sequences of the combined α and β subunits of the E1 enzyme of the pyruvate dehydrogenase complexes of Homo sapiens and Bacillus stearothermophilus aligned well with the ...
Robinson, Brian H., Chun, Kathy
openaire   +2 more sources

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