Control of mitochondrial respiration [PDF]
The control theory of Kacser and Burns [in: Rate Control of Biological Processes (Davies, D.D. ed) pp. 65–104, Cambridge University Press, London, 1973] and Heinrich and Rapoport ([Eur. J. Biochem. (1974) 42, 97‐105] has been used to quantify the amount of control exerted by different steps on mitochondrial oxidative phosphorylation in rat‐liver ...
Tager, J.M. +9 more
+8 more sources
Effect of remifentanil on mitochondrial oxygen consumption of cultured human hepatocytes. [PDF]
During sepsis, liver dysfunction is common, and failure of mitochondria to effectively couple oxygen consumption with energy production has been described.
Siamak Djafarzadeh +3 more
doaj +1 more source
Protocol for Measurement of Oxygen Consumption Rate In Situ in Permeabilized Cardiomyocytes
Summary: Analysis of mitochondrial respiration function represented by the oxygen consumption rate is necessary for assessing mitochondrial respiration function.
Meng Gao +4 more
doaj +1 more source
PurposeMuscle biopsies are the gold standard to assess mitochondrial respiration; however, biopsies are not always a feasible approach in persons with spinal cord injury (SCI).
Raymond E Lai +5 more
doaj +2 more sources
RationaleThe main purposes of this study were to compare mitochondrial respiration in M. triceps brachii and M. vastus lateralis between elite cross-country (XC) skiers and physically active controls (CON), and to explore the associations between ...
Jonathan Berg +7 more
doaj +1 more source
Modulation of Human Sperm Mitochondrial Respiration Efficiency by Plant Polyphenols
Plant bioactives, such as polyphenols, can differentially affect (positively or negatively) sperm quality, depending on their concentration. These molecules have been proposed as natural scavengers of reactive oxygen species (ROS) for male infertility ...
Alessandra Ferramosca +8 more
doaj +1 more source
Metformin Improves Mitochondrial Respiratory Activity through Activation of AMPK
Summary: Impaired mitochondrial respiratory activity contributes to the development of insulin resistance in type 2 diabetes. Metformin, a first-line antidiabetic drug, functions mainly by improving patients’ hyperglycemia and insulin resistance. However,
Yu Wang +11 more
doaj +1 more source
KATP Channel Openers Have Opposite Effects on Mitochondrial Respiration Under Different Energetic Conditions [PDF]
Mitochondrial (m) KATP channel opening has been implicated in triggering cardiac preconditioning. Its consequence on mitochondrial respiration, however, remains unclear. We investigated the effects of two different KATP channel openers and antagonists on
Camara, Amadou K.S. +5 more
core +2 more sources
Ergosterol reduction impairs mitochondrial DNA maintenance in S. cerevisiae [PDF]
Sterols are essential lipids, involved in many biological processes. In Saccharomyces cerevisiae, the enzymes of the ergosterol biosynthetic pathway (Erg proteins) are localized in different cellular compartments.
Balliano, Gianni +6 more
core +2 more sources
Mutations in valosin-containing protein (VCP) decrease ADP/ATP translocation across the mitochondrial membrane and impair energy metabolism in human neurons [PDF]
Mutations in the gene encoding valosin-containing protein (VCP) lead to multisystem proteinopathies including frontotemporal dementia. We have previously shown that patient-derived VCP mutant fibroblasts exhibit lower mitochondrial membrane potential ...
Abramov +43 more
core +2 more sources

