Results 111 to 120 of about 1,557,014 (330)

An Intravesical Akkermansia muciniphila‐Based Chemo‐Immunotherapeutic Platform for Bladder Cancer

open access: yesAdvanced Science, EarlyView.
Pasteurized Akkermansia muciniphila is engineered into an intravesical F127/doxorubicin platform that couples localized chemotherapy with immune remodeling. By inducing apoptosis, ferroptosis, and immunogenic cell death, this chemo‐immunotherapeutic system enhances dendritic‐cell maturation, antigen cross‐presentation, and tumor‐specific CD8+ T‐cell ...
Rongkang Li   +11 more
wiley   +1 more source

A Micropeptide Component of the OGDH Complex Modulates ATP Production in the TCA Cycle

open access: yesAdvanced Science, EarlyView.
This study identified a mitochondrial micropeptide encoded by a non‐canonical open reading frame (alt‐ORF) within the CTSB gene. This micropeptide named APPM (ATP production‐promoting micropeptide) is a novel component of the OGDHc complex in the TCA cycle. APPM localizes to the inner mitochondrial membrane and directly binds to OGDH, the E1 subunit of
Xinqiang Yin   +9 more
wiley   +1 more source

ДНК как модулятор протонной проницаемости на внутренней мембране митохондрий Solanum tuberosum, действующий на уровне переносчика адениннуклеотидов

open access: yesФактори експериментальної еволюції організмів, 2014
Aims. To study the potential metabolic consequences of DNA import into mitochondria we investigated the effect of 200 bp length DNA on the permeability of inner membrane of tuber mitochondria in Solanum tuberosum in comparison with such an effect of ...
М. В. Кулинченко   +4 more
doaj  

Ventilator-induced lung injury results in oxidative stress response and mitochondrial swelling in a mouse model. [PDF]

open access: yesLab Anim Res, 2022
Joelsson JP   +9 more
europepmc   +1 more source

Novel cyclophilin D inhibitors derived from quinoxaline exhibit highly inhibitory activity against rat mitochondrial swelling and Ca2+ uptake/release

open access: yesActa Pharmacologica Sinica, 2005
Aim:To investigate methods for identifying specific cyclophilin D (CypD) inhibitors derived from quinoxaline, thus developing possible lead compounds to inhibit mitochondrial permeability transition (MPT) pore opening.Methods:Kinetic analysis of the CypD/
Hong-Ming Guo   +7 more
semanticscholar   +1 more source

Mitochondrial swelling during cold exposure of the rat and hamster

open access: yes, 1962
Swelling of isolated liver mitochondria of hamsters and rats was measured in a Beckman DK ratio-recording spectrophotometer after 0, 1, 2, 5, 10, 15, and 20 days of cold exposure at 5 C.
Joseph B. Boatman   +2 more
core   +1 more source

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

open access: yesAdvanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou   +9 more
wiley   +1 more source

Ultrastructural lesions in the myocardium and kidneys of rabbits in experimental acute Amorimia exotropica poisoning

open access: yesPesquisa Veterinária Brasileira, 2016
: Amorimia exotropica is an important plant associated with sudden death in cattle in Southern Brazil. In order to understand the mechanisms by which A.
Mauro P. Soares   +6 more
doaj   +1 more source

Mitochondrial membrane permeability and DNA content.

open access: yes, 2021
Mitochondrial membrane permeability was determined by hypotonically induced mitochondrial swelling and the absorption changes were followed spectrophotometrically at 540nm [20,31].
Chris Hogg (384355)   +4 more
core   +1 more source

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