Results 51 to 60 of about 10,797 (208)
Sensing of cardiolipin exposure on plasma membranes of apoptotic cells by EryA‐mCherry protein
An aegerolysin protein erylysin A (EryA) fused with mCherry binds to artificial lipid vesicles supplemented with cardiolipin (CL). This binding is much more specific than that of annexin V, which binds various negatively charged glycerophospholipids (PG, PS, PI). In mammalian cells, the CL exposition at the membrane surface represents an early hallmark
Luka Žeželj +12 more
wiley +1 more source
PURPOSE: The aim of the present study was to assess the advantages and disadvantages of liver vascular partial exclusion (LVPE) (liver dysfunction due to ischemia) during liver resection in patients submitted to partial hepatectomy.
Orlando Castro e Silva +7 more
doaj +1 more source
Novel heterozygous mutation in the steroidogenic acute regulatory protein gene in a 46,XY patient with congenital lipoid adrenal hyperplasia [PDF]
StAR forma parte del complejo multiproteico transduceosoma, encargado del transporte de colesterol y que facilita su entrada a la mitocondria. Mutaciones recesivas en el gen STAR causan formas clásicas y no clásicas de hiperplasia adrenal congénita ...
Bailez, Marcela +10 more
core +1 more source
Psoriasis‐like inflammation induces structural and functional changes in mitochondria
Psoriasis‐like inflammation, induced by IL‐17, IL‐22, and TNF‐α in keratinocytes and fibroblasts, alters mitochondrial functions, suppressing respiration and increasing mitochondrial ROS production. It also triggers mitochondrial fragmentation, swelling, and cristae disassembly, alongside enhanced secretion of proinflammatory mediators driven by ...
Gabrielė Kulkovienė +10 more
wiley +1 more source
Las UCPs: una nueva vía para el tratamiento de la obesidad [PDF]
Los avances recientes en el conocimiento de los mecanismos que controlan el peso corporal han de llevar al desarrollo de nuevas terapias para el tratamiento de la obesidad. En el presente artículo se describe cómo el descubrimiento de la UCP2 y UCP3, dos
Rial, Eduardo
core
A comprehensive overview of yeast libraries and their role in advancing cell biology
Systematic, genome‐wide yeast mutant libraries have revolutionized systems and cell biology. By allowing high‐throughput interrogation of every gene and protein, they have defined gene essentiality, charted protein localization, illuminated function, mapped interactions, and more.
Din Baruch, Maya Schuldiner, Ofir Klein
wiley +1 more source
Efecto del aceite esencial de Eucalyptus citriodora sobre el metabolismo energético mitocondrial
Con el fin de contribuir al conocimiento de su actividad a nivel celular, se evaluó el mecanismo de acción del aceite esencial de Eucalyptus citriodora (Fam.
Luis Carlos Vesga +3 more
doaj +1 more source
Mitocondriopatías: las manifestaciones de una organela enferma. ¿Quién hace el diagnóstico? [PDF]
Las enfermedades mitocondriales son relativamente comunes y resultan de defectos en la cadena respiratoria de esa organela. Sus manifestaciones pueden ser multisistémicas o localizadas en un solo tejido. Además, pueden ser adquiridas en forma esporádica
Altamirano, Eugenia
core
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Investigaciones internacionales Nutrial 2010
Las manzanas son fuente rica de procianidinas (Pcy), un tipo de flavonoides que inhiben la promoción/progresión de la carcinogénesis de colon en ratas.Como los mecanismos celulares y moleculares mediante los cuales esto ocurre no son bien conocidos, se ...
María Elena Maldonado Cells +4 more
doaj

