Results 61 to 70 of about 458,508 (146)

Differential effects of ERK and p38 signaling in BMP-2 stimulated hypertrophy of cultured chick sternal chondrocytes [PDF]

, 2005
Background During endochondral bone formation, the hypertrophy of chondrocytes is accompanied by selective expression of several genes including type X collagen and alkaline phosphatase.
Golden, E.B., Grasso-Knight, G., Leboy, P.S., Reilly, G.C.   +3 more
core   +3 more sources

The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival.

Biochemical Journal, 1998
The mammalian response to stress is complex, often involving multiple signalling pathways that act in concert to influence cell fate. To examine potential interactions between the signalling cascades, we have focused on the effects of a model oxidant ...
Xiantao Wang, J. Martindale, Yusen Liu, N. Holbrook   +3 more
semanticscholar   +1 more source

Octacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes [PDF]

, 2005
Basic calcium phosphate (BCP) crystals, including hydroxyapatite, octacalcium phosphate (OCP) and carbonate-apatite, have been associated with severe osteoarthritis and several degenerative arthropathies.
Ea, Hang-Korng, Lioté, Frédéric, Rey, Christian, Uzan, Benjamin   +3 more
core   +6 more sources

Adult Human Mesenchymal Stem Cell Differentiation to the Osteogenic or Adipogenic Lineage Is Regulated by Mitogen-activated Protein Kinase*

Journal of Biological Chemistry, 2000
Adult human mesenchymal stem cells are primary, multipotent cells capable of differentiating to osteocytic, chondrocytic, and adipocytic lineages when stimulated under appropriate conditions.
R. Jaiswal, N. Jaiswal, S. Bruder, G. Mbalaviele, D. Marshak, M. Pittenger   +5 more
semanticscholar   +1 more source

Rapid activation of protein kinase C in isolated rat liver nuclei by prolactin, a known hepatic mitogen. [PDF]

, 1988
Arthur R. Buckley, Paul D. Crowe, Diane H. Russell   +2 more
openalex   +1 more source

Dihydrotestosterone stimulates amino acid uptake and the expression of LAT2 in mouse skeletal muscle fibres through an ERK1/2-dependent mechanism [PDF]

, 2011
Dihydrotestosterone (DHT) has acute/non-genomic actions in adult mammalian skeletal muscles whose physiological functions are still poorly understood.
Anthony, Avruch, Baird, Barber, Beugnet, Bhasin, Bhasin, Bhasin, Biolo, Bradford, Bruchovsky, Brunet, Christensen, Christensen, Chun, Dann, Deak, Drummond, Drummond, Edmondson, Estrada, Exner, Exner, Ferrando, Ferrando, Franchi-Gazzola, Franchi-Gazzola, Fryburg, Fuller, G. Mutungi, Gazzola, Glass, Hamdi, Harper, Heinlein, Horio, Hyde, Hyde, Hyde, Jiang, Kashiwagi, Kochakian, Krishna, M. M. Hamdi, Mackenzie, McGivan, Mendelsohn, Moule, Mutungi, Palacin, Palii, Pineda, Ravikumar, Regnier, Saartok, Salmons, Schneider-Poetsch, Segawa, Shepherd, Sugawara, Thigpen, Utsunomiya-Tate, Wagner, Wilson, Yao   +64 more
core   +1 more source

Engineered single nucleotide polymorphisms in the mosquito MEK docking site alter Plasmodium berghei development in Anopheles gambiae. [PDF]

, 2014
BackgroundSusceptibility to Plasmodium infection in Anopheles gambiae has been proposed to result from naturally occurring polymorphisms that alter the strength of endogenous innate defenses.
Anishchenko, Michael, Brault, Aaron C, Brenton, Ashley A, Cheung, Kong, Luckhart, Shirley, Souvannaseng, Lattha   +5 more
core   +3 more sources

Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1 (*)

Journal of Biological Chemistry, 1995
The stress-activated p38 mitogen-activated protein (MAP) kinase defines a subgroup of the mammalian MAP kinases that appear to play a key role in regulating inflammatory responses.
Shengjia Zhang, Jiahuai Han, M. A. Sells, J. Chernoff, U. Knaus, R. Ulevitch, G. Bokoch   +6 more
semanticscholar   +1 more source

Cardiac Muscle Cell Hypertrophy and Apoptosis Induced by Distinct Members of the p38 Mitogen-activated Protein Kinase Family*

Journal of Biological Chemistry, 1998
p38 mitogen-activated protein (MAP) kinase activities were significantly increased in mouse hearts after chronic transverse aortic constriction, coincident with the onset of ventricular hypertrophy.
Yibin Wang, Shuang Huang, V. Sah, J. Ross, J. Brown, Jiahuai Han, K. Chien   +6 more
semanticscholar   +1 more source

p42 mitogen-activated protein kinase and p90 ribosomal S6 kinase are selectively phosphorylated and activated during thrombin-induced platelet activation and aggregation. [PDF]

, 1994
J Papkoff, R H Chen, John Blenis, John Forsman   +3 more
openalex   +1 more source