Antioxidant and anti-inflammatory effects in RAW264.7 macrophages of malvidin, a major red wine polyphenol. [PDF]
PLoS ONE, 2013 Red wine polyphenols can prevent cardiovascular and inflammatory diseases. Resveratrol, the most extensively studied constituent, is unlikely to solely account for these beneficial effects because of its rather low abundance and bioavailability. Malvidin
Eszter Bognar +7 more
doaj +9 more sources
In-silico genome wide analysis of Mitogen activated protein kinase kinase kinase gene family in C. sinensis [PDF]
PLoS ONE, 2021 Mitogen activated protein kinase kinase kinase (MAPKKK) form the upstream component of MAPK cascade. It is well characterized in several plants such as Arabidopsis and rice however the knowledge about MAPKKKs in tea plant is largely unknown.
Abhirup Paul +4 more
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Mitogen-activated protein kinase kinase 7 in inflammatory, cancer, and neurological diseases [PDF]
Frontiers in Cell and Developmental Biology, 2022 Stress-activated mitogen-activated protein kinase kinase 7 (MKK7) is a member of the dual-specificity mitogen-activated protein kinase family. In the human body, MKK7 controls essential physiological processes, including but not limited to proliferation ...
Amada D. Caliz +6 more
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Mitogen-Activated Protein Kinase Kinase Kinase 1 Overexpression Disrupts Development of the Ocular Surface Epithelium [PDF]
CellsMitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1) is a key signaling molecule essential for eyelid closure during embryogenesis. In mice, Map3k1 knockout leads to a fully penetrant eye-open at birth (EOB) phenotype due to disrupted MAPK signaling,
Maureen Mongan +4 more
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Mitogen-activated protein kinase signaling in plant pathogenic fungi. [PDF]
PLoS Pathogens, 2018 Like in other eukaryotic organisms, mitogen-activated protein (MAP) kinase cascades play important roles in response to host and environmental signals in fungal pathogens.
Cong Jiang +3 more
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RelA and mitogen-activated protein kinase kinase kinases potently enhance lentiviral vector production [PDF]
Biochemistry and Biophysics ReportsThe growing demands for gene therapy have encouraged development of safe and efficient lentiviral vector (LV) preparation. While much progress has been made in this field, it remains to be explored how to boost its production from producer cells.
Shoji Yamaoka
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Mitogen-Activated Protein Kinase Cascades in Plant Hormone Signaling
Frontiers in Plant Science, 2018 Mitogen-activated protein kinase (MAPK) modules play key roles in the transduction of environmental and developmental signals through phosphorylation of downstream signaling targets, including other kinases, enzymes, cytoskeletal proteins or ...
Przemysław Jagodzik +4 more
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Knockdown of Mitogen-Activated Protein Kinase Kinase 3 Negatively Regulates Hepatitis A Virus Replication. [PDF]
Int J Mol Sci, 2021 Kanda T +6 more
europepmc +3 more sources
Rice mitogen activated protein kinase kinase and mitogen activated protein kinase interaction network revealed by in-silico docking and yeast two-hybrid approaches. [PDF]
PLoS ONE, 2013 Protein-protein interaction is one of the crucial ways to decipher the functions of proteins and to understand their role in complex pathways at cellular level.
Dhammaprakash Pandhari Wankhede +3 more
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Mitogen-activated protein kinases regulate susceptibility to ventilator-induced lung injury. [PDF]
PLoS ONE, 2008 Mechanical ventilation causes ventilator-induced lung injury in animals and humans. Mitogen-activated protein kinases have been implicated in ventilator-induced lung injury though their functional significance remains incomplete. We characterize the role
Tamás Dolinay +9 more
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