Results 271 to 280 of about 402,236 (378)

Mitogen-activated protein kinase signaling in plant pathogenic fungi. [PDF]

PLoS Pathogens, 2018
Cong Jiang, Xue Zhang, Huiquan Liu, Jin-Rong Xu   +3 more
doaj   +1 more source

Yanhusuo extract inhibits metastasis of breast cancer cells by modulating mitogen-activated protein kinase signaling pathways

, 1994
Lee
openalex   +2 more sources

Glucose Deprivation-induced Cytotoxicity and Alterations in Mitogen-activated Protein Kinase Activation Are Mediated by Oxidative Stress in Multidrug-resistant Human Breast Carcinoma Cells [PDF]

, 1998
Yong J. Lee, Sandra Galoforo, Christine M. Berns, Jenn C. Chen, Bruce H. Davis, Julia Sim, Peter M. Corry, Douglas R. Spitz   +7 more
openalex   +1 more source

Development of a Peptide Inhibitor Targeting the C‐SH2 Domain of the SHP2 Phosphatase

ChemBioChem, Accepted Article.
Src homology 2 (SH2) domain‐containing phosphatase 2 (SHP2) mediates important signal transduction upon cell surface receptor stimulation, regulating multiple cellular functions. In addition to the catalytically active phosphotyrosine (pTyr) phosphatase domain, SHP2 contains two regulatory pTyr‐binding domains: the N‐SH2 and C‐SH2 domains.
Azin Kiani, Catia L. Pierotti, Franziska Schedel, Thomas Kokot, Judith Weyershaeuser, Mario Brehm, Pablo Rios, Kerstin Fehrenbach, Bettina Warscheid, Susana Minguet, Wolfgang W. Schamel, Maja Köhn   +11 more
wiley   +1 more source

Reduced virulence of Candida albicans MKC1 mutants: a role for mitogen-activated protein kinase in pathogenesis [PDF]

, 1997
Rosalía Diez‐Orejas, Gloria Molero, Federico Navarro, Jesús Plá, César Nombela, Miguel Sánchez‐Pérez   +5 more
openalex   +1 more source

Impact of Mutational Status on Intracellular Effects of Cell‐Permeable CaaX Peptides in Pancreatic Cancer Cells

ChemBioChem, EarlyView.
This work deals with intracellular effects of cell‐permeable CaaX‐peptides, designed to influence prenylated proteins like KRas. The results show that after CaaX‐1 treatment, not only KRas expression and signaling are specifically altered in mutated pancreatic cancer cells, but also plasma membrane localization of KRas is affected.
Merlin Klußmann, Martin Matijass, Ines Neundorf   +2 more
wiley   +1 more source

p38 Mitogen-activated Protein Kinase Phosphorylates Cytosolic Phospholipase A2 (cPLA2) in Thrombin-stimulated Platelets [PDF]

, 1996
Ruth M. Kramer, Edda F. Roberts, Suzane L. Um, Angelika Börsch-Haubold, Steve P. Watson, Matthew J. Fisher, Joseph A. Jakubowski   +6 more
openalex   +1 more source

A Proteomics Profiling Reveals the Neuroprotective Effects of Melatonin on Exogenous β‐amyloid‐42 Induced Mitochondrial Impairment, Intracellular β‐amyloid Accumulation and Tau Hyperphosphorylation in Human SH‐SY5Y Cells

Cell Biology International, EarlyView.
ABSTRACT Alzheimer's disease (AD) is prevalent in the elderly population and characterized by the intracellular accumulation of neurofibrillary tangles (NFTs), composed of tau proteins, and extracellular deposition of beta‐amyloid protein (Aβ). The present study aimed to investigate the neuroprotective effects of melatonin on Aβ42‐induced AD‐like ...
Jiraporn Panmanee, Matthew Phanchana, Phorutai Pearngam, Nopphon Petchyam, Kornkanok Promthep, Ponlawit Wisomka, Suchanoot Kutpruek, Supitcha Pannengpetch, Tanya Prasertporn, Sujira Mukda, Piyarat Govitrapong, Chutikorn Nopparat   +11 more
wiley   +1 more source

Inducing cyclooxygenase-2 expression, prostaglandin E₂ and prostaglandin F_2α production of human dental pulp cells by activation of toll-like receptor-3, mitogen-activated protein kinase kinase/extracellular signal-regulated kinase and p38 signaling. [PDF]

J Dent Sci
Chang MC, Wu JH, Chen SY, Hsu YT, Yeung SY, Pan YH, Jeng JH.   +6 more
europepmc   +1 more source

Activation of the p38 Mitogen-activated Protein Kinase Pathway by Epstein-Barr Virus-encoded Latent Membrane Protein 1 Coregulates Interleukin-6 and Interleukin-8 Production [PDF]

, 1999
Aristides G. Eliopoulos, Neil J. Gallagher, Sarah M.S. Blake, William O. Dawson, Lawrence S. Young   +4 more
openalex   +1 more source