Results 281 to 290 of about 402,236 (378)

Whole‐genome CRISPR‐Cas9 knockout screens identify SHOC2 as a genetic dependency in NRAS‐mutant melanoma

Cancer Communications, EarlyView.
Andrea Y. Gu, Tet Woo Lee, Aziza Khan, Xuenan Zhang, Francis W. Hunter, Dean C. Singleton, Stephen M. F. Jamieson   +6 more
wiley   +1 more source

Inorganic Metal Nanoparticles in Reproductive Biology: Applications, Toxicities and Future Prospects

ChemPlusChem, EarlyView.
Metal nanoparticles (MNPs) have shown great promise in the livestock industry such as semen collection, nano‐purification, cryopreservation, sex sorting, bioimaging, drug and gene delivery. However, reproductive toxicity induced by MNP has adverse effects on various sexual functions including poor sperm parameters, testicular damage, ovary injury, and ...
Sangita Kundu, Wilfried A. Kues, Christoph Rehbock, Stephan Barcikowski   +3 more
wiley   +1 more source

Vascular endothelial growth factor stimulates prostacyclin production and activation of cytosolic phospholipase A₂ in endothelial cells via p42/p44 mitogen‐activated protein kinase [PDF]

, 1997
Caroline Wheeler‐Jones, Robin ABU-GHAZALEH, Rosario Cospedal, Rebecca A. Houliston, John F. Martin, Ian Zachary   +5 more
openalex   +1 more source

An Iron‐Catalyzed Sustainable Functional Group Transfer Strategy for In‐Water Transformation of Organic Sulfides to Sulfoxides by a Hydroxylamine‐Derived Oxidant

ChemSusChem, EarlyView.
An iron‐catalyzed ecofriendly reaction protocol is demonstrated to chemoselectively convert readily available organic sulfides to valuable sulfoxides, under mild reaction conditions in water. The functional group tolerance, scalability, reaction compatibility, and potential application make the protocol highly attractive in terms of green and ...
Arya Singh, Yashdeep Maurya, Akhilesh Sharma, Swetha Vasanthdamodar Sivapreetha, Mehar Ul Nisa, Vishal Kumar, Puneet Gupta, Kartikay Tyagi, Sayanti Chatterjee   +8 more
wiley   +1 more source

Activation pattern of mitogen‐activated protein kinases elicited by peroxynitrite: attenuation by selenite supplementation [PDF]

, 1999
Stefan M. Schieke, Karlis Briviba, Lars‐Oliver Klotz, Helmut Sies   +3 more
openalex   +1 more source

Association of ventricular–arterial coupling with biomarkers involved in heart failure pathophysiology – the STANISLAS cohort

European Journal of Heart Failure, EarlyView.
Association of ventricular–arterial coupling with heart failure (HF) biomarkers in the STANISLAS cohort. MMP, matrix metalloproteinase; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide. Aims Impaired left ventricular–arterial coupling (VAC) has been shown to correlate with worse prognosis in cardiac diseases and heart failure (HF).
Hannes Holm, Martin Magnusson, Amra Jujić, Jérémy Lagrange, Erwan Bozec, Zohra Lamiral, Emmanuel Bresso, Olivier Huttin, Guillaume Baudry, Luca Monzo, Patrick Rossignol, Faiez Zannad, Nicolas Girerd   +12 more
wiley   +1 more source

Harnessing autophagy to overcome mitogen-activated protein kinase kinase inhibitor-induced resistance in metastatic melanoma. [PDF]

Br J Dermatol, 2019
Verykiou S, Alexander M, Edwards N, Plummer R, Chaudhry B, Lovat PE, Hill DS.   +6 more
europepmc   +1 more source

Rapid and Delayed p42/p44 Mitogen-Activated Protein Kinase Activation by Nitric Oxide: The Role of Cyclic GMP and Tyrosine Phosphatase Inhibition [PDF]

, 1998
Dagmar Callsen, Josef Pfeilschifter, Bernhard Brüne   +2 more
openalex   +1 more source

Benzochalcogenodiazoles, synthesis and applications in medicinal chemistry and photomedicine.

European Journal of Organic Chemistry, Accepted Article.
Benzochalcogenodiazoles BXDs (BOD: benzoxadiazole, BTD: benzothiadiazole, or BSD: benzoselenadiazole) are aromatic bicyclic compounds, containing chalcogen atoms, with applications ranging from material to medicinal chemistry. The recent developments in their preparation and functionalization are taking advantage of new methodologies such as C‐H ...
Jean-Elie Zheng, Xavier Franck, Thibault Gallavardin   +2 more
wiley   +1 more source

Mitogen-activated protein kinase kinase 6 negatively regulates anthocyanin induction in Arabidopsis. [PDF]

Plant Signal Behav, 2018
Wersch RV, Gao F, Zhang Y.
europepmc   +1 more source