Results 211 to 220 of about 234,943 (363)

PCFT Independent Cellular Uptake of Cyclic Cell Penetrating Peptide Conjugated Folic Acid

ChemBioChem, Accepted Article.
Folic acid is an essential component of many metabolic processes, including the synthesis of nucleoproteins, purines, and pyrimidines and is a recommended supplement to lower the incidence of various disorders. Folic acid and folate loaded nanoparticles are extensively evaluated for sustained release and enhanced stability of the molecule, however ...
Vineet Kumar Mishra, Rheal Towner, Juan Carlos Rodriguez-Lecompte, Marya Ahmed   +3 more
wiley   +1 more source

Functional coupling of SSTR4, a major hippocampal somatostatin receptor, to adenylate cyclase inhibition, arachidonate release and activation of the mitogen-activated protein kinase cascade.

, 1994
Haruhiko Bito, M Mori, Chie Sakanaka, Tomoko Takano, Zen-ichiro Honda, Yukiko Gotoh, Eisuke Nishida, Takao Shimizu   +7 more
openalex   +1 more source

Hallmarks of Neuroblastoma—Pathophysiology, Diagnosis, and Therapeutic Interventions

Cancer Nexus, EarlyView.
ABSTRACT Neuroblastoma, the most common extracranial solid tumor in childhood, continues to challenge clinicians and researchers because of its heterogeneous nature and complex pathophysiology. Recent breakthroughs in molecular profiling revealed intricate genetic alterations driving tumor progression, necessitating an updated perspective on the ...
Abhimanyu Thakur, Anne Dijkstra
wiley   +1 more source

An Iron‐Catalyzed Sustainable Functional Group Transfer Strategy for In‐Water Transformation of Organic Sulfides to Sulfoxides by a Hydroxylamine‐Derived Oxidant

ChemSusChem, EarlyView.
An iron‐catalyzed ecofriendly reaction protocol is demonstrated to chemoselectively convert readily available organic sulfides to valuable sulfoxides, under mild reaction conditions in water. The functional group tolerance, scalability, reaction compatibility, and potential application make the protocol highly attractive in terms of green and ...
Arya Singh, Yashdeep Maurya, Akhilesh Sharma, Swetha Vasanthdamodar Sivapreetha, Mehar Ul Nisa, Vishal Kumar, Puneet Gupta, Kartikay Tyagi, Sayanti Chatterjee   +8 more
wiley   +1 more source

Protein Kinases as Mediators for miRNA Modulation of Neuropathic Pain. [PDF]

Cells
Chang L, Čok Z, Yu L.
europepmc   +1 more source

Transcriptional Activation by Peroxisome Proliferator-activated Receptor γ Is Inhibited by Phosphorylation at a Consensus Mitogen-activated Protein Kinase Site [PDF]

, 1997
Maria Adams, Mauricio J. Reginato, Dalei Shao, Mitchell A. Lazar, Krishna Chatterjee   +4 more
openalex   +1 more source

Whole‐genome CRISPR‐Cas9 knockout screens identify SHOC2 as a genetic dependency in NRAS‐mutant melanoma

Cancer Communications, EarlyView.
Andrea Y. Gu, Tet Woo Lee, Aziza Khan, Xuenan Zhang, Francis W. Hunter, Dean C. Singleton, Stephen M. F. Jamieson   +6 more
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Differential Roles of Ca²⁺/Calmodulin-Dependent Protein Kinase II and Mitogen-Activated Protein Kinase Activation in Hippocampal Long-Term Potentiation [PDF]

, 1999
Jie Liu, Kohji Fukunaga, Hideyuki Yamamoto, Katsuhide Nishi, Eishichi Miyamoto   +4 more
openalex   +1 more source

miR-369-3p Ameliorates Inflammation and Apoptosis in Intestinal Epithelial Cells via the MEK/ERK Signaling Pathway. [PDF]

Int J Mol Sci
Scalavino V, Piccinno E, Giannelli G, Serino G.   +3 more
europepmc   +1 more source