Results 151 to 160 of about 424,108 (316)

Chronic high‐fat diet induces multi‐organ dysfunction and metabolic homeostasis disruption in Macaca fascicularis

Animal Models and Experimental Medicine, EarlyView.
An 18‐month HFD successfully established a translational Macaca fascicularis model replicating key metabolic disorders (MASH, diabetes, cardiac hypertrophy). MASH was determined by liver biopsy histology, the presence steatosis, inflammatory infiltration, hepatocytic ballooning, and fibrosis were considered as MASH; diabetes was diagnosed according to ...
Hongyi Chen, Wei Liu, Dan Zhou, Shuhua Liu, Yalun Guan, Zongyu Miao, Lei Cai, Xuejiao Li, Yunfeng Li, Zhongqiang Huang, Yi Jin, Ge Li, Yu Zhang   +12 more
wiley   +1 more source

Regulation of Arabidopsis Matrix Metalloproteinases by Mitogen-Activated Protein Kinases and Their Function in Leaf Senescence. [PDF]

Front Plant Sci, 2022
Wu H, Si Q, Liu J, Yang L, Zhang S, Xu J.   +5 more
europepmc   +1 more source

Trametinib in Adults with Neurofibromatosis Type 1‐Related Symptomatic Plexiform Neurofibromas

Annals of Neurology, EarlyView.
Objective Mitogen‐activated protein kinase kinase inhibitors have shown promising results in treatment of plexiform neurofibromas in neurofibromatosis type 1 patients, but data in adults are limited. The aim of this phase 2 study was to investigate the efficacy and safety of trametinib in adults with neurofibromatosis type 1.
D. Christine Noordhoek, David F. Hanff, Pim J. French, Sarah A. van Dijk, Erik A.C. Wiemer, Olivier C. Manintveld, Martin J. van den Bent, Walter Taal   +7 more
wiley   +1 more source

Functional analysis of mitogen-activated protein kinases (MAPKs) in potato under biotic and abiotic stress. [PDF]

Mol Breed, 2022
Majeed Y, Zhu X, Zhang N, Rasheed A, Tahir MM, Si H.   +5 more
europepmc   +1 more source

Induction of Mitogen-activated Protein Kinase Phosphatase-1 by Arachidonic Acid in Vascular Smooth Muscle Cells [PDF]

, 1998
Bernhard Metzler, Yanhua Hu, Gertraud Sturm, Georg Wick, Qingbo Xu   +4 more
openalex   +1 more source

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

Microbiology and Molecular Reviews, 2011
Marie Cargnello, Philippe P Roux
semanticscholar   +1 more source

Assessing Angiogenic Properties In Vitro or In Ovo of Pre‐Crosslinked Alginate‐Dialdehyde‐Gelatin Hydrogels Incorporating Boron‐Doped Mesoporous Bioactive Glass Particles

Advanced NanoBiomed Research, EarlyView.
This study examines the influence of boron‐doped mesoporous bioactive glass nanoparticles (MBGN) blended in cast and 3D‐printed pre‐crosslinked alginate‐dialdehyde‐gelatin (ADA‐GEL). Addition of 0.5% and 1% MBGN did not negatively affect the viability of human umbilical vein endothelial cells (HUVECs), or the sprouting of HUVEC spheroids.
Rafael Schmid, Yvonne Kulicke, Evelin Sandor, Hsuan‐Heng Lu, Stefan Fleischer, Isabell Lang, Harald Wajant, Hana Kaňková, Andreas Arkudas, Annika Kengelbach‐Weigand, Raymund E. Horch, Aldo R. Boccaccini, Theresa Promny   +12 more
wiley   +1 more source

Mitogen-Activated Protein Kinases Associated Sites of Tobacco Repression of Shoot Growth Regulates Its Localization in Plant Cells. [PDF]

Int J Mol Sci, 2022
Wang L, Gui Y, Yang B, Dong W, Xu P, Si F, Yang W, Luo Y, Guo J, Niu D, Jiang C.   +10 more
europepmc   +1 more source

p38 Mitogen-Activated Protein Kinase-Dependent Chemokine Production, Leukocyte Recruitment, and Hepatocellular Apoptosis in Endotoxemic Liver Injury

, 2005
Daniel Klintman, Xiang Li, Stefan Santén, René Schramm, Bengt Jeppsson, Henrik Thorlacius   +5 more
openalex   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source