Results 171 to 180 of about 423,744 (290)

Differential activation of protein kinase C isoforms by endothelin-1 and phenylephrine and subsequent stimulation of p42 and p44 mitogen-activated protein kinases in ventricular myocytes cultured from neonatal rat hearts

, 1994
Angela Clerk, Marie A. Bogoyevitch, Martin Anderson, P H Sugden   +3 more
openalex   +1 more source

Characterization of a mitogen‐activated protein (MAP) kinase from Plasmodium falciparum [PDF]

, 1997
Ralph Graeser, Patrick Ku ̈ry, Richard M. Franklin, Barbara Kappes   +3 more
openalex   +1 more source

Bridging the Gap Between Human Toxicology and Ecotoxicology Under One Health Perspective by a Cross‐Species Adverse Outcome Pathway Network for Reproductive Toxicity

Environmental Toxicology and Chemistry, EarlyView.
Cross‐species extrapolation of adverse outcome pathway network on reproductive toxicity under the One Health perspective using new approach methodologies. AOP = adverse outcome pathway. Abstract Although ecotoxicological and toxicological risk assessments are performed separately from each other, recent efforts have been made in both disciplines to ...
Elizabeth Dufourcq Sekatcheff, Jaeseong Jeong, Jinhee Choi   +2 more
wiley   +1 more source

Targeting a key protein-protein interaction surface on mitogen-activated protein kinases by a precision-guided warhead scaffold. [PDF]

Nat Commun
Póti ÁL, Bálint D, Alexa A, Sok P, Ozsváth K, Albert K, Turczel G, Magyari S, Ember O, Papp K, Király SB, Imre T, Németh K, Kurtán T, Gógl G, Varga S, Soós T, Reményi A.   +17 more
europepmc   +1 more source

Contributions of Sodium-Hydrogen Exchanger 1 and Mitogen-Activated Protein Kinases to Enhanced Retinal Venular Constriction to Endothelin-1 in Diabetes. [PDF]

Diabetes, 2021
Chen YL, Ren Y, Rosa RH, Kuo L, Hein TW.
europepmc   +1 more source

Nerve growth factor stimulates the activities of the raf-1 and the mitogen-activated protein kinases via the trk protooncogene.

, 1992
M Ohmichi, Long Pang, Stuart J. Decker, Alan R. Saltiel   +3 more
openalex   +1 more source

Activation of mitogen‐activated protein kinase by protein kinase C isotypes α, β_I and γ, but not ϵ [PDF]

, 1996
Stephen W. Young, Martin Dickens, Jeremy M. Tavaré   +2 more
openalex   +1 more source

Innovative PDK1‐Degrading PROTACs Transform Cancer Aerobic Glycolysis and Induce Immunogenic Cell Death in Breast Cancer

Exploration, EarlyView.
In this study, A04, a compound targeting the degradation of metabolic enzyme PDK1, was developed by PROTAC technology, which significantly inhibited tumor proliferation by disrupting the Warburg effect in cancer cells. In the mouse model, A04 could prolong postoperative survival, and also remodel the immunosuppressive microenvironment, which could ...
Aohua Deng, Renming Fan, Jiakui Gou, Ruoxi Sang, Ruizhuo Lin, Ting Zhao, Junyan Zhuang, Yongrui Hai, Jialin Sun, Gaofei Wei   +9 more
wiley   +1 more source

Identification of mitogen-activated protein kinases substrates in Arabidopsis using kinase client assay. [PDF]

Plant Signal Behav
Bahk S, Ahsan N, An J, Kim SH, Ramadany Z, Hong JC, Thelen JJ, Chung WS.   +7 more
europepmc   +1 more source

Retracted: Resistin-Like Molecule Beta (RELM-β) Regulates Proliferation of Human Diabetic Nephropathy Mesangial Cells via Mitogen-Activated Protein Kinases (MAPK) Signaling Pathway. [PDF]

Med Sci Monit, 2022
Wang YQ, Fan CC, Chen BP, Shi J.
europepmc   +1 more source