Results 1 to 10 of about 40,063 (99)

Exosomal Long Non-coding RNA HOTTIP Increases Resistance of Colorectal Cancer Cells to Mitomycin via Impairing MiR-214-Mediated Degradation of KPNA3

open access: yesFrontiers in Cell and Developmental Biology, 2021
It has been reported that long non-coding RNA HOXA distal transcript antisense RNA (lncRNA HOTTIP) functions as a tumor promoter in colorectal cancer (CRC).
Xi-juan Chen   +8 more
semanticscholar   +1 more source

Repurposed Antimicrobial Combination Therapy: Tobramycin-Ciprofloxacin Hybrid Augments Activity of the Anticancer Drug Mitomycin C Against Multidrug-Resistant Gram-Negative Bacteria

open access: yesFrontiers in Microbiology, 2019
The lack of therapeutic options to treat infections caused by multidrug-resistant (MDR) pathogens, especially Gram-negative bacteria, is apparent. Therefore, it is imperative to develop new strategies to address the problem of antimicrobial resistance ...
Ronald Domalaon   +5 more
semanticscholar   +1 more source

Mitomycin C in the Endoscopic Treatment of Laryngotracheal Stenosis: Systematic Review and Proportional Meta-Analysis

open access: yesInternational Archives of Otorhinolaryngology, 2019
Introduction Mitomycin C is a natural antibiotic that has been used to inhibit the proliferation of fibroblasts in scar tissue. Objective To evaluate the effectiveness and safety of topical Mitomycin C as an adjuvant in the endoscopic treatment of ...
T. Queiroga   +4 more
semanticscholar   +1 more source

Mitomycin C in pterygium treatment.

open access: yesInternational Journal of Ophthalmology, 2016
Pterygium is a benign lesion usually growing from the nasal side of the conjunctiva onto the cornea. Most cases of pterygium does not cause problem or requires specific treatment.
T. Martins   +4 more
semanticscholar   +1 more source

Intravesical bacillus Calmette-Guerin versus mitomycin C for Ta and T1 bladder cancer.

open access: yesCochrane Database of Systematic Reviews, 2015
BACKGROUND Tumour recurrence following transurethral resection (TUR) for Ta and T1 bladder cancer is a major clinical problem. Intravesical administration of mitomycin C (MMC) or bacillus Calmette-Guerin (BCG) has proven prophylactic activity but both ...
S. Schmidt   +8 more
semanticscholar   +1 more source

A review of the efficacy of mitomycin C in glaucoma filtration surgery

open access: yesClinical Ophthalmology, 2015
The success of trabeculectomy, which is considered the gold standard in the surgical treatment of glaucoma, depends on the wound healing response. The introduction of antiproliferative agents such as mitomycin C (MMC) has increased the success rates of ...
Ahmed Al Habash   +3 more
semanticscholar   +1 more source

Mitomycin C versus 5-Fluorouracil for wound healing in glaucoma surgery.

open access: yesCochrane Database of Systematic Reviews, 2015
BACKGROUND Raised intraocular pressure is a risk factor for glaucoma. One treatment option is glaucoma drainage surgery (trabeculectomy). Antimetabolites are used during surgery to reduce postoperative scarring during wound healing.
Emily Cabourne   +3 more
semanticscholar   +1 more source

Prevention of Intraabdominal Adhesions: An Experimental Study Using Mitomycin-C and 4% Icodextrin

open access: yesBalkan Medical Journal, 2016
Background: Intraabdominal adhesions remain a significant cause of morbidity and mortality. Moreover, intraabdominal adhesions can develop in more than 50% of abdominal operations.
M. Urkan   +6 more
semanticscholar   +1 more source

Pegylated liposomal mitomycin C prodrug enhances tolerance of mitomycin C: a phase 1 study in advanced solid tumor patients

open access: yesCancer Medicine, 2015
Mitomycin C (MMC) has potent cytotoxicity but cumulative toxicity limits widespread use. In animals, pegylated liposomal mitomycin C lipid‐based prodrug (PL‐MLP) was well tolerated and more effective than free MMC.
T. Golan   +8 more
semanticscholar   +1 more source

Biodegradable 3D-Porous Collagen Matrix (Ologen) Compared with Mitomycin C for Treatment of Primary Open-Angle Glaucoma: Results at 5 Years

open access: yesJournal of Ophthalmology, 2015
Purpose. To evaluate the effectiveness and safety of the Ologen as an aid for trabeculectomy performed for primary open-angle glaucoma compared with mitomycin C. Methods. In this prospective, randomized, parallel assignment, comparative study, 31 eyes of
Fei Yuan   +4 more
semanticscholar   +1 more source

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