Results 21 to 30 of about 100,295 (288)

Mitomycin C Inhibits Esophageal Fibrosis by Regulating Cell Apoptosis and Autophagy via lncRNA-ATB and miR-200b

Frontiers in Molecular Biosciences, 2021
Benign esophageal strictures (BESs) frequently results from esophageal fibrosis. The transformation of fibroblasts into fibrocyte is an important cause of fibrosis. The treatment of fibrosis is challenging.
Yin Zhang, Yin Zhang, Qinge Wang, Qinge Wang, Yuping Xu, Yuping Xu, Jing Sun, Jing Sun, Yanbo Ding, Yanbo Ding, Li Wang, Li Wang, Bingfang Chen, Bingfang Chen, Kewen Sun, Kewen Sun, Jianping Chen, Jianping Chen   +17 more
doaj   +1 more source

Sarcoma in a Patient with Laryngeal Papillomatosis: A Case Report [PDF]

Iranian Journal of Otorhinolaryngology, 2022
Introduction:Recurrent respiratory papillomatosis (RRP) is classically described as a benign neoplasm of the larynx. Nevertheless, transformation to dysplasia and invasive carcinoma can occur. Sarcoma of the larynx is rare.
Eleana Tzoi, Konstantinos Garefis, Vasileios Nikolaidis, Ourania Mpatsi, Konstantinos Markou   +4 more
doaj   +1 more source

Application of mitomycin in the treatment of cicatricial complications after radical prostatectomy

Андрология и генитальная хирургия, 2014
At a choice of a way of treatment of the localized prostate cancer not the last place is occupied by an assessment of possible complications after the executed operation.
Yu. G. Alyaev, L. M. Rapoport, D. G. Tsarichenko, A. V. Artemov   +3 more
doaj   +3 more sources

Loco-regional deep hyperthermia combined with intravesical Mitomycin instillation reduces the recurrence of non-muscle invasive papillary bladder cancer

International Journal of Hyperthermia, 2021
Objectives To compare the therapeutic effects of locoregional deep hyperthermia combined with intravesical chemotherapy with those of intravesical chemotherapy alone in patients with intermediate-/high-risk non-muscle invasive bladder cancer (NMIBC).
Yu-Ching Wen, Liang-Ming Lee, Yung-Wei Lin, Syuan-Hao Syu, Ke-Hsun Lin, Yen-Chun Fan, Hsin-Lun Lee, Benjamin Chung Howe Lai, Hung-Jen Shih   +8 more
doaj   +1 more source

Mitomycin C in Homologous Recombination Deficient Metastatic Pancreatic Cancer after Disease Progression on Platinum-Based Chemotherapy and Olaparib

Biomedicines, 2022
Recent efforts to personalize treatment with platinum-based chemotherapy and PARP inhibitors have produced promising results in homologous recombinant deficient (HRD) metastatic pancreatic cancer (MPC).
Gehan Botrus, Denise Roe, Gayle S. Jameson, Pedro Luiz Serrano Uson Junior, Ronald Lee Korn, Lana Caldwell, Taylor Bargenquast, Max Miller, Erkut Hasan Borazanci   +8 more
doaj   +1 more source

Determination of the Protein-Protein Interactions within Acyl Carrier Protein (MmcB)-Dependent Modifications in the Biosynthesis of Mitomycin

Molecules, 2021
Mitomycin has a unique chemical structure and contains densely assembled functionalities with extraordinary antitumor activity. The previously proposed mitomycin C biosynthetic pathway has caused great attention to decipher the enzymatic mechanisms for ...
Dongjin Leng, Yong Sheng, Hengyu Wang, Jianhua Wei, Yixin Ou, Zixin Deng, Linquan Bai, Qianjin Kang   +7 more
doaj   +1 more source

Effects of Mitomycin C in Early Conjunctival Inflammation after Pterygium Surgery [PDF]

, 2016
Purpose: The purpose of this study was to compare inflammatory events and graft characteristics 1 month and 6 months after conjunctival limbal autograft (CLAU) with and without intraoperative mitomycin C (MMC).
Asaad Ammaar, Mouafk, Campos, Pamela, da Costa Paula, Claudia, Julio Morán, Gemma, Pujol Vives, Pere   +4 more
core   +2 more sources

Mitosene-DNA adducts. Characterization of two major DNA monoadducts formed by 1,10-bis(acetoxy)-7-methoxymitosene upon reductive activation [PDF]

, 1997
Reductive activation of racemic 1,10-bis(acetoxy)-7-methoxymitosene WV15 in the presence of DNA, followed by enzymatic digestion and HPLC analysis, revealed the formation of various DNA adducts.
Duynhoven, John P.M. van, Gargiulo, Dario, Janssen, Lambert H.M., Maliepaard, Marc, Mol, Nico J. de, Reinhoudt, David N., Tomasz, Maria, Velzen, Ewoud J.J. van, Verboom, Willem   +8 more
core   +2 more sources

Lycopene treatment of prostate cancer cell lines inhibits adhesion and migration properties of the cells [PDF]

, 2014
licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.
Chopra, Mridula, Cooper, Alan, Elgass, Simone   +2 more
core   +1 more source

Phase I study of everolimus and mitomycin C for patients with metastatic esophagogastric adenocarcinoma [PDF]

, 2013
This study aimed at determining the recommended dose of the mammalian target of rapamycin inhibitor everolimus in combination with mitomycin C (MMC) in patients with previously treated metastatic esophagogastric cancer.
Atmaca, Akin, Batran, Salah-Eddin al-, Jäger, Elke, Pauligk, Claudia, Pustowka, Anette, Werner, Dominique   +5 more
core   +1 more source