UBR2 of the N-end rule pathway is required for chromosome stability via histone ubiquitylation in spermatocytes and somatic cells [PDF]
, 2012 The N-end rule pathway is a proteolytic system in which its recognition components (N-recognins) recognize destabilizing N-terminal residues of short-lived proteins as an essential element of specific degrons, called N-degrons.
An, JY +12 more
core +1 more source
Journal of Research in Pharmacy Practice, 2020 Objective: To evaluate the recurrence rate and outcome of pterygium surgery with amniotic membrane transplantation (AMT) and intraoperative mitomycin C (MMC).
Hasan Razmjoo +3 more
doaj +1 more source
DNA double strand breaks but not interstrand crosslinks prevent progress through meiosis in fully grown mouse oocytes [PDF]
, 2012 There is some interest in how mammalian oocytes respond to different types of DNA damage because of the increasing expectation of fertility preservation in women undergoing chemotherapy.
Julie A. Merriman +4 more
core +6 more sources
Differentiation of Fanconi Anaemia (FA) from Idiopathic Aplastic Anaemia by Mitomycin - C (MMC) Stress Test [PDF]
Walawalkar International Medical Journal, 2020 Introduction and Background: Fanconi Anaemia (FA), an autosomal recessive disorder is one of the most common amongst hereditary causes of idiopathic aplastic anaemia with a worldwide incidence of 1 in 1, 60,000 individuals.
Sowmya Gayatri C1,2, Ashwin B. Dalal1 and Usha R. Dutta1
doaj
Curcumin improved liposomal mitomycin-induced cell toxicity in bladder cancer cell [PDF]
Nanomedicine Journal, 2018 Objective (s): This study aimed at investigation of preparation and stability study of Mitomycin and Mitomycin loaded nanoliposems and efficacy of the combination of Mitomycin -loaded nanoliposomes and Curcumin versus Mitomycin in suppressing HTB-9 and ...
Farjad Amanolahi +4 more
doaj +1 more source
EFFICACY OF SEQUENTIAL BCG AND MITOMYCIN VERSUS MITOMYCIN ALONE FOR TREATMENT OF SUPERFICIAL BLADDER CANCER [PDF]
Basrah Journal of Surgery, 2012 A study to compare the efficacy and local toxicity of combining anticancer drugs immunotherapy and chemotherapy (Sequential BCG and mitomycin c) versus mitomycin alone in the treatment of superficial bladder cancer after complete transurethral resection.
Hazim R Akal
doaj +1 more source
Antitumor effect of therapeutic HPV DNA vaccines with chitosan-based nanodelivery systems [PDF]
, 2014 Cervical cancer is the second-most-common cause of malignancies in women worldwide, and the oncogenic activity of the human papilloma virus types (HPV) E7 protein has a crucial role in anogenital tumors.
Atyabi, F. +8 more
core +3 more sources
Urological Science, 2019 Objectives: To evaluate the efficacy of instillations with mitomycin C (MMC) or bacillus Calmette–Guérin (BCG) in patients with T1 high-grade bladder cancer (BC).
Li-Wen Chang +10 more
doaj +1 more source
Frequency analysis of cytolytic T cell precursors (CTL-P) generated in vivo during lethal rabies infection of mice. I. Distinction of CTL-P with different interleukin 2 sensitivity [PDF]
, 1982 The aim of this study was to determine the number and state of activity of cytolytic T lymphocytes (CTL) and their precursors (CTL-P) present in vivo during the early stages of viral infection. The local response to lethal infection with rabies virus was
Cerottini +21 more
core +1 more source
Canaloplasty in the Treatment of Open-Angle Glaucoma: A Review of Patient Selection and Outcomes. [PDF]
, 2018 Canaloplasty is a relatively new non-penetrating surgery for the reduction of intraocular pressure in patients affected by glaucoma. The technique uses a microcatheter to perform a 360 º cannulation of Schlemm's canal and leaves in place a tension suture
Brusini, Paolo +5 more
core +2 more sources