Results 61 to 70 of about 59,323 (260)

Mitomycins syntheses: a recent update

Beilstein Journal of Organic Chemistry, 2009
Mitomycins are a class of very potent antibacterial and anti-cancer compounds having a broad activity against a range of tumours. They have been used in clinics since the 1960’s, and the challenges represented by their total synthesis have challenged ...
Jean-Christophe Andrez
doaj   +1 more source

Augmenting trabeculectomy in glaucoma with subconjunctival mitomycin C versus subconjunctival 5-fluorouracil: a randomized clinical trial

, 2011
Ali MostafaeiNikoukari Ophthalmology University Hospital, Tabriz University of Medical Sciences, Tabriz, IranObjective: The aim of this study was to compare the efficacy of augmenting trabeculectomy with subconjunctival mitomycin C (TMMC) versus 5 ...
Ali Mostafaei, Mostafaei A
core   +1 more source

Drug‐coated balloons: From conventional designs to next‐generation innovations in vascular therapy

BMEMat, EarlyView.
This review traces the evolution of drug‐coated balloons (DCBs) from conventional designs to next‐generation platforms. We highlight innovations in balloon engineering, coating technologies, and therapeutic agents that enhance localized drug delivery while addressing challenges in efficiency, safety, and biocompatibility for vascular and emerging non ...
Lu Zhang, Jiawei Cui, Jin Wang, Manfred F. Maitz, Rifang Luo, Yunbing Wang   +5 more
wiley   +1 more source

Monosubstituted N‐Arylhydroxylamine Chemistry: Integrating Contemporary Synthetic Approaches for the Efficient Construction of Diverse Heterocyclic Scaffolds

Chemistry – A European Journal, EarlyView.
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis, Kyriakos D. Nikopoulos, Ioannis N. Lykakis   +2 more
wiley   +1 more source

Peptide RL‐QN15 Regulates Functions of Epidermal Stem Cells to Accelerate Skin Wound Regeneration via the FZD8/β‐Catenin Axis

Exploration, EarlyView.
Amphibian‐derived peptide RL‐QN15 activates the Wnt/β‐catenin signaling pathway by interacting with the FZD8 membrane receptor, promoting epidermal stem cells proliferation, migration, stemness, and EMT processes, thus promoting skin wound healing.
Yuansheng Li, Qiuye Jia, Naixin Liu, Saige Yin, Junyuan Wang, Yujing Ding, Yuliu Yang, Ying Peng, Zeqiong Ru, Shaoyang Zhang, Bu'er Qi, Jun Sun, Li He, Ying Wang, Kun Guo, Xinwang Yang   +15 more
wiley   +1 more source

Postoperative umbilical cord serum eye drops versus intraoperative mitomycin-C in photorefractive keratectomy for moderate myopia

Journal of the Egyptian Ophthalmological Society
Purpose To evaluate the efficacy and safety of umbilical cord serum (UCS) eye drops compared with intraoperative mitomycin-C (MMC) in enhancing corneal epithelial healing, reducing stromal haze, and improving early postoperative outcomes following ...
Taher K. Eleiwa, Kareem M. Abdelghany, Amr I. Sharawy   +2 more
doaj   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Heat-activated intravenous liposomal doxorubicin combined with mitomycin C hyperthermic intravesical chemotherapy (HIVEC) for treatment of bladder cancer

International Journal of Hyperthermia
Purpose To evaluate the safety and pharmacokinetics of lyso-thermosensitive liposomal doxorubicin (LTLD, ThermoDox®) combined with mitomycin C (MMC) hyperthermic intravesical chemotherapy (HIVEC) as a potential treatment for non-muscle invasive bladder ...
Andrew S. Mikhail, Sandeep Gurram, Vladimir A. Valera, Dieter Haemmerich, Nikhil Gopal, Ivane Bakhutashvili, William Richardson, Cody J. Peer, Matthew F. Starost, Charles Hesswani, Keith T. Schmidt, William D. Figg, John W. Karanian, William F. Pritchard, Bradford J. Wood   +14 more
doaj   +1 more source

Mitomycin C induces apoptosis in human epidural scar fibroblasts after surgical decompression for spinal cord injury

Neural Regeneration Research, 2017
Numerous studies have shown that topical application of mitomycin C after surgical decompression effectively reduces scar adhesion. However, the underlying mechanisms remain unclear.
Tao Sui, Da-wei Ge, Lei Yang, Jian Tang, Xiao-jian Cao, Ying-bin Ge   +5 more
doaj   +1 more source

Inflammatory Markers may Determine Postoperative Complications in Cases of Peritoneal Carcinomatosis of Ovarian Origin Treated With Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives This study aimed to evaluate the ability of perioperative inflammatory markers to discriminate postoperative complications within 6 months in patients with ovarian cancer–related peritoneal metastasis undergoing cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC).
Donmez Mustafa, Bisgin Tayfun, Manoglu Berke, Sokmen Selman, Sensoy Basoglu Ecem, Boztas Nilay, Ozgul Ozkardesler Sevda   +6 more
wiley   +1 more source