Results 71 to 80 of about 59,323 (260)

Autophagy Plays a Suppressive Role in Bladder Tumor Formation in an Orthotopic Mouse Model and Bladder Cancer Patient Specimens

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Autophagy plays either a suppressing or promoting role during tumor development. Clarifying the role of autophagy in bladder tumorigenesis both in vitro and in vivo is crucial for developing novel therapeutic strategies through manipulating autophagy activity.
Wan‐Ting Kuo, Chin‐Chen Pan, Yi‐Wen Liu, Nan‐Haw Chow, Hong‐Lin Cheng, Shan‐Ying Wu, Sheng‐Hui Lan, Chih‐Peng Chang, Hsiao‐Sheng Liu   +8 more
wiley   +1 more source

Mitomycin extravasation injury: A case series

JAAD Case Reports, 2021
Karolina Mieczkowska, BS, Alana Deutsch, BA, Bijal Amin, MD, Adnan Mir, MD, PhD, Renu Abraham, PharmD, Yevgeniy Balagula, MD, Rachel Blasiak, MD, MPH, Ranon E. Mann, MD, Parth Patel, MD, Tagai Musaev, MD, Tian Hao Zhu, MD, Shalom Kalnicki, MD, Stuart H. Packer, MD, Beth N. McLellan, MD   +13 more
doaj   +1 more source

Efficacy of mitomycin-C on anterior urethral stricture after internal urethrotomy: A systematic review and meta-analysis [version 3; peer review: 1 approved, 2 approved with reservations]

F1000Research, 2020
Background and Aim Mitomycin-C is a potent agent that plays an important role in tissue healing and scar formation. This study aims to investigate the efficacy of Mitomycin-C in treating anterior urethral stricture after internal urethrotomy.
Irfan Wahyudi, Gampo Alam Irdam, Andy Andy   +2 more
doaj   +1 more source

Tailoring Targeted Therapy to Individual Patients: Lessons to be Learnt from the Development of Mitomycin C

, 2007
The modern era of targeted therapeutics offers the potential to tailor therapy to individual patients whose tumours express a specific target. Previous attempts to forecast tumour response to conventional chemotherapeutics based on similar principles ...
Phillips, Roger M, Volpato, Milene
core  

The use of mitomycin C with autologous limbal-conjunctival autograft transplantation for management of recurrent pterygium

, 2011
Mohamed A FakhryDepartment of Ophthalmology, Kasr El Aini Hospital, Cairo University, Cairo, EgyptPurpose: The purpose of this study is to evaluate and compare recurrence rates upon using mitomycin C (MMC) with limbal-conjunctival autograft for treating ...
Mohamed A Fakhry, Mohamed Fakhry
core   +1 more source

Safety Evaluation of an Aqueous Root and Leaf Extract of Ashwagandha (Withania somnifera)

Phytotherapy Research, EarlyView.
Sensoril, an aqueous root and leaf extract of ashwagandha showed no evidence of mutagenicity in the in vitro Ames assay, was negative in the in vitro micronucleus, in vivo mammalian bone marrow chromosome aberration assays, and was well tolerated in the rat at up to 4000 mg/kg BW/day when administered orally for a period of 90 days. The data from these
Mukesh Summan, Candace L. Doepker, Gregory P. Brorby   +2 more
wiley   +1 more source

Natural Products as Modulators of ABC Transporters in Breast Cancer

Phytotherapy Research, EarlyView.
ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan, Reyhaneh Farghadani, Ammu K. Radhakrishnan   +2 more
wiley   +1 more source

Mitomycin C in the Endoscopic Treatment of Laryngotracheal Stenosis: Systematic Review and Proportional Meta-Analysis

International Archives of Otorhinolaryngology, 2020
Introduction Mitomycin C is a natural antibiotic that has been used to inhibit the proliferation of fibroblasts in scar tissue. Objective To evaluate the effectiveness and safety of topical Mitomycin C as an adjuvant in the endoscopic ...
Thereza L. O. Queiroga, Daniele C. Cataneo, Regina H. G. Martins, Tarcisio A. Reis, Antônio J. M. Cataneo   +4 more
doaj   +1 more source

Preclinical Toxicity Screening of Sodium Dodecanoyloxybenzenesulfonate (LOBS) as a New Alternative Biocide Using In Vitro and In Vivo Models

Environmental Toxicology, EarlyView.
ABSTRACT Sodium hypochlorite is a well‐established biocide extensively used in both living and industrial environments; however, exposure to it or improper handling can harm the human body and the environment. Thus, safer alternatives to sodium hypochlorite are required.
Seung Eui Min, Seunghee Oh, Min Seong Jang, Kang‐Hyun Han   +3 more
wiley   +1 more source

The Protective Effect of Silibinin Against Mitomycin C–Induced Intrinsic Apoptosis in Human Melanoma A375-S2 Cells

Journal of Pharmacological Sciences, 2009
Silibinin is known for its hepatoprotective, anti-inflammatory, and anti-carcinogenic effects. We found that silibinin exhibited a protective effect against chemotherapeutic reagent mitomycin C–induced cell death in A375-S2 cells in a p53-dependent ...
Yuan-yuan Jiang, Hong-jun Wang, Jing Wang, Shin-ichi Tashiro, Satoshi Onodera, Takashi Ikejima   +5 more
doaj   +1 more source