Results 51 to 60 of about 13,879 (218)

Anterior chamber flare and central macular thickness after trabeculectomy versus after phacoemulsification

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To compare the inflammatory response in the eye after trabeculectomy to after phacoemulsification, focusing on anterior chamber flare (AC flare) and central macular thickness (CMT). Methods Data from 436 participants in two randomized controlled trials were analysed.
Yasmeen Ahmed   +5 more
wiley   +1 more source

Cytotoxicity, crosslinking and biological activity of three mitomycins. [PDF]

open access: yesBioorg Chem, 2022
Cheng SY   +12 more
europepmc   +1 more source

Risk of metachronous upper tract urothelial carcinoma following non‐muscle‐invasive bladder cancer

open access: yesBJU International, EarlyView.
Objective To determine the risk and timing of metachronous upper tract urothelial carcinoma (UTUC) after non‐muscle‐invasive bladder cancer (NMIBC). Patients and Methods In this multi‐institutional retrospective cohort study involving academic and community hospitals, clinicopathological data were collected from patients with NMIBC treated between 2005
Keiran J.C. Pace   +22 more
wiley   +1 more source

Mechanism of action studies on the FR-9000482 class of antitumor antibiotics [PDF]

open access: yes, 1997
1997 Summer.Includes bibliographical references.The interactions of members of the FR-900482 class of antitumor antibiotic agents with DNA has been examined. Importantly, the first in vitro demonstration of nucleic acid interstrand cross-linking has been
Rajski, Scott Raymond
core  

Inhibition of Fibroblast Activation Protein‐α Ameliorates Intervertebral Disc Degeneration via Reduced Vascular Invasion in Cartilage Endplate

open access: yesCell Proliferation, EarlyView.
Schematic illustration showing that FAP‐α promoted angiogenesis, cytokine release and ECM degradation in the CEP degeneration of the intervertebral disc through upregulating the PI3K/Akt/HIF‐1α/VEGFA pathway. ABSTRACT Intervertebral disc degeneration (IDD) is a primary cause of low back pain, with the development of new blood vessels being a key ...
Hao‐Wei Xu   +4 more
wiley   +1 more source

Limited roles of the miR‐17‐92 cluster in the regulation of T‐cell apoptosis

open access: yesThe FEBS Journal, EarlyView.
The pro‐apoptotic protein BIM shapes T‐cell survival and function, but how it is regulated remains unclear. In a mouse model lacking direct miR‐17‐92:Bim interactions, we observed a moderate reduction in Th17 CD4+ T cells. BIM levels were modestly increased in double‐positive thymocytes and naive CD8+ T cells, but this did not affect overall T‐cell ...
Katharina Hoppe   +7 more
wiley   +1 more source

Total Synthesis of 6,7-Dimethyl-N-Methyl Aziridinomitosene [PDF]

open access: yes, 2018
Mitomycin C (MC) is a naturally occurring antitumor agent isolated from a soil bacterium. MC is effective against solid hypoxic tumors that respond poorly to radiotherapy, such as colorectal, gastric, and lung tumors. Also, it has a role in the treatment
Muhammed, Thaaer N.
core   +1 more source

From bacterial predators to partners: phages in agriculture

open access: yesNew Phytologist, EarlyView.
Summary Bacteriophages, viruses that infect bacteria, are critical players for shaping the taxonomic and functional composition of plant‐associated microbiomes. Yet, their roles in plant health remain overlooked, along with their implications for sustainable agriculture.
Zahra Salehimoghaddam   +2 more
wiley   +1 more source

Harnessing blue light photobiomodulation for cancer therapy: Evidence from a systematic review

open access: yesPhotochemistry and Photobiology, EarlyView.
Conventional treatments for various types of cancer are often associated with tumor recurrence and aggressiveness. Photobiomodulation with blue light (BL; 450–470 nm) emerges as a promising alternative with antitumor effects. This systematic review, with 37 in vitro and in vivo studies from 2002 to 2024, revealed that BL reduces cell viability ...
Bárbara Evelyn Santos de Lima   +6 more
wiley   +1 more source

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