Results 51 to 60 of about 380,556 (390)
Computer-Aided Assessment of Melanocytic Lesions by Means of a Mitosis Algorithm
Diagnostics, 2022 An increasing number of pathology laboratories are now fully digitised, using whole slide imaging (WSI) for routine diagnostics. WSI paves the road to use artificial intelligence (AI) that will play an increasing role in computer-aided diagnosis (CAD ...
Bart Sturm +9 more
doaj +1 more source
Mitosis Detection in Breast Cancer Histology Images via Deep Cascaded Networks
AAAI Conference on Artificial Intelligence, 2016 The number of mitoses per tissue area gives an important aggressiveness indication of the invasive breast carcinoma.However, automatic mitosis detection in histology images remains a challenging problem. Traditional methods either employ hand-crafted
Hao Chen +4 more
semanticscholar +1 more source
Closed mitosis requires local disassembly of the nuclear envelope
bioRxiv, 2019 At the end of mitosis, eukaryotic cells must segregate the two copies of their replicated genome into two new nuclear compartments 1 . They do this either by first dismantling and later reassembling the nuclear envelope in an ‘open mitosis’ or by ...
Gautam Dey +5 more
semanticscholar +1 more source
Chromatin proteins and RNA are associated with DNA during all phases of mitosis. [PDF]
, 2016 Mitosis brings about major changes to chromosome and nuclear structure. We used recently developed proximity ligation assay-based techniques to investigate the association with DNA of chromatin-associated proteins and RNAs in Drosophila embryos during ...
Brock, Hugh W +6 more
core +3 more sources
Open Biology, 2022 Lamin A phosphorylation/de-phosphorylation is an important process during cells division as it allows for nuclear envelope (NE) disassembly at mitotic entry and its re-assembly during mitotic exit.
Florentin Huguet +4 more
doaj +1 more source
Fcp1 phosphatase controls Greatwall kinase to promote PP2A-B55 activation and mitotic progression
eLife, 2015 During cell division, progression through mitosis is driven by a protein phosphorylation wave. This wave namely depends on an activation-inactivation cycle of cyclin B-dependent kinase (Cdk) 1 while activities of major protein phosphatases, like PP1 and ...
Rosa Della Monica +4 more
doaj +1 more source
Epithelial tricellular junctions act as interphase cell shape sensors to orient mitosis
Nature, 2016 The orientation of cell division along the long axis of the interphase cell—the century-old Hertwig’s rule—has profound roles in tissue proliferation, morphogenesis, architecture and mechanics.
Floris Bosveld +12 more
semanticscholar +1 more source
DNA damage induced during mitosis undergoes DNA repair synthesis. [PDF]
, 2020 Understanding the mitotic DNA damage response (DDR) is critical to our comprehension of cancer, premature aging and developmental disorders which are marked by DNA repair deficiencies.
Berns, Michael W +10 more
core +1 more source
Phosphatases in Mitosis: Roles and Regulation
Biomolecules, 2019 Mitosis requires extensive rearrangement of cellular architecture and of subcellular structures so that replicated chromosomes can bind correctly to spindle microtubules and segregate towards opposite poles.
Margarida Moura, Carlos Conde
semanticscholar +1 more source
A dynamic mode of mitotic bookmarking by transcription factors. [PDF]
, 2016 During mitosis, transcription is shut off, chromatin condenses, and most transcription factors (TFs) are reported to be excluded from chromosomes. How do daughter cells re-establish the original transcription program? Recent discoveries that a select set
An, Luye +5 more
core +1 more source