Mad2, Bub3, and Mps1 regulate chromosome segregation and mitotic synchrony in Giardia intestinalis, a binucleate protist lacking an anaphase-promoting complex. [PDF]
The binucleate pathogen Giardia intestinalis is a highly divergent eukaryote with a semiopen mitosis, lacking an anaphase-promoting complex/cyclosome (APC/C) and many of the mitotic checkpoint complex (MCC) proteins.
Cande, W Zacheus, Vicente, Juan-Jesus
core +2 more sources
CLASP promotes microtubule bundling in metaphase spindle independently of Ase1/PRC1 in fission yeast
Microtubules in the mitotic spindle are organised by microtubule-associated proteins. In the late stage of mitosis, spindle microtubules are robustly organised through bundling by the antiparallel microtubule bundler Ase1/PRC1. In early mitosis, however,
Hirohisa Ebina, Liang Ji, Masamitsu Sato
doaj +1 more source
In this study, a commercial insecticide, Altach 5EC, has been used to investigate its cytotoxic effects on chromosomes and mitosis of cells in the root tip of Allium fistulosum L.
NGUYEN Thi Thao, NGUYEN Thi Tam
doaj +1 more source
Mitosis Detection for Breast Cancer Pathology Images Using UV-Net [PDF]
The difficulty of detecting mitosis and its similarity to non-mitosis objects has remained a challenge in computational pathology. The lack of publicly available data has added more complexity. Deep learning algorithms have shown potentials in mitosis detection tasks.
arxiv
Differential expression of conserved germ line markers and delayed segregation of male and female primordial germ cells in a hermaphrodite, the leech helobdella. [PDF]
In sexually reproducing animals, primordial germ cells (PGCs) are often set aside early in embryogenesis, a strategy that minimizes the risk of genomic damage associated with replication and mitosis during the cell cycle.
Cho, Sung-Jin+2 more
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Recent Research Advances in Mitosis during Mammalian Gametogenesis
Mitosis is a highly sophisticated and well-regulated process during the development and differentiation of mammalian gametogenesis. The regulation of mitosis plays an essential role in keeping the formulation in oogenesis and gametogenesis.
Jia-Hao Wang+5 more
doaj +1 more source
Phosphorylation of AIB1 at mitosis is regulated by CDK1/CYCLIN B. [PDF]
Although the AIB1 oncogene has an important role during the early phase of the cell cycle as a coactivator of E2F1, little is known about its function during mitosis.Mitotic cells isolated by nocodazole treatment as well as by shake-off revealed a post ...
Macarena Ferrero+6 more
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Novel CRK-Cyclin Complex Controls Spindle Assembly Checkpoint in Toxoplasma Endodyogeny
Opportunistic parasites of the Apicomplexa phylum use a variety of division modes built on two types of cell cycles that incorporate two distinctive mechanisms of mitosis: uncoupled from and coupled to parasite budding.
Lauren M. Hawkins+5 more
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A Novel Dataset and a Deep Learning Method for Mitosis Nuclei Segmentation and Classification [PDF]
Mitosis nuclei count is one of the important indicators for the pathological diagnosis of breast cancer. The manual annotation needs experienced pathologists, which is very time-consuming and inefficient. With the development of deep learning methods, some models with good performance have emerged, but the generalization ability should be further ...
arxiv
Comprehensive identification of SUMO2/3 targets and their dynamics during mitosis. [PDF]
During mitosis large alterations in cellular structures occur rapidly, which to a large extent is regulated by post-translational modification of proteins.
Julie Schou+4 more
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