Results 81 to 90 of about 286,319 (230)

Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery [PDF]

, 2014
Copyright @ 2014 Booth et al. This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.When the nucleolus ...
Adolph, Angelier, Booth, Booth, Bridger, Chaly, Chamousset, Chubb, Croft, Dowsett, Dundr, Dundr, Earnshaw, Elbashir, Endl, Fomproix, Gassmann, Gautier, Gautier, Gautier, Gautier, Gerdes, Green, Harrison, Hendrickx, Hernandez-Verdun, Hernandez-Verdun, Hudson, Isola, Jewell, Jiang, Johnson, Kalmarova, Kametaka, Kill, Krause, Kutay, Louvet, Ma, MacCallum, MacCallum, MacCallum, McKeon, Miron, Moorhead, Moyne, Negi, Ohta, Pfaff, Qian, Ramos-Echazabal, Reboutier, Saiwaki, Samejima, Savino, Scholzen, Schrader, Sumner, Szebeni, Takagi, Takagi, Tokuyama, Trinkle-Mulcahy, Vagnarelli, Vagnarelli, Vagnarelli, Van Hooser, Vanneste, Verheijen, Verheijen, Wanner, Wurzenberger, Yasuda   +72 more
core   +4 more sources

Spatial signals link exit from mitosis to spindle position

eLife, 2016
In budding yeast, if the spindle becomes mispositioned, cells prevent exit from mitosis by inhibiting the mitotic exit network (MEN). The MEN is a signaling cascade that localizes to spindle pole bodies (SPBs) and activates the phosphatase Cdc14.
Jill Elaine Falk, Dai Tsuchiya, Jolien Verdaasdonk, Soni Lacefield, Kerry Bloom, Angelika Amon   +5 more
doaj   +1 more source

Mitosis algorithm for Grothendieck polynomials [PDF]

arXiv, 2015
In this article we will introduce the way to extend the mitosis algorithm for Schubert polynomials, developed by Ezra Miller, to the case of Grothendieck polynomials.
arxiv  

Improving Mitosis Detection Via UNet-based Adversarial Domain Homogenizer [PDF]

arXiv, 2022
The effective localization of mitosis is a critical precursory task for deciding tumor prognosis and grade. Automated mitosis detection through deep learning-oriented image analysis often fails on unseen patient data due to inherent domain biases.
arxiv  

Phosphorylation of survivin at threonine 34 inhibits its mitotic function and enhances its cytoprotective activity [PDF]

, 2009
Survivin is an essential chromosomal passenger protein required for mitotic progression. It is also an inhibitor of apoptosis and can prevent caspase-mediated cell death.
Barrett, Rachel M.A., Osborne, Toby P., Wheatley, Sally P.   +2 more
core   +1 more source

Regulation of mRNA translation during mitosis

eLife, 2015
Passage through mitosis is driven by precisely-timed changes in transcriptional regulation and protein degradation. However, the importance of translational regulation during mitosis remains poorly understood. Here, using ribosome profiling, we find both
Marvin E Tanenbaum, Noam Stern-Ginossar, Jonathan S Weissman, Ronald D Vale   +3 more
doaj   +1 more source

Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules [PDF]

, 2017
Tubulin-targeting molecules are widely used cancer therapeutic agents. They inhibit microtubule-based structures, including the mitotic spindle, ultimately preventing cell division.
Coluccia, Antonio, Cundari, Enrico, DI CESARE, Erica, Famiglini, Valeria, Giubettini, Maria, LA REGINA, Giuseppe, Lavia, Patrizia, Miele, Andrea, Rovella, Paola, Silvestri, Romano, Verrico, Annalisa   +10 more
core   +1 more source

Fission yeast neddylation ligase Dcn1 facilitates cohesin cleavage and chromosome segregation at anaphase

Biology Open, 2017
Post-translational protein modification such as phosphorylation and ubiquitination are critical during mitosis to ensure proper timing and progression of chromosome segregation.
Lan Lin, Li Chen, Phong T. Tran
doaj   +1 more source

A dynamic mode of mitotic bookmarking by transcription factors. [PDF]

, 2016
During mitosis, transcription is shut off, chromatin condenses, and most transcription factors (TFs) are reported to be excluded from chromosomes. How do daughter cells re-establish the original transcription program? Recent discoveries that a select set
An, Luye, Darzacq, Xavier, Hansen, Anders S, Teves, Sheila S, Tjian, Robert, Xie, Liangqi   +5 more
core   +1 more source

Leveraging Unlabeled Whole-Slide-Images for Mitosis Detection [PDF]

arXiv, 2018
Mitosis count is an important biomarker for prognosis of various cancers. At present, pathologists typically perform manual counting on a few selected regions of interest in breast whole-slide-images (WSIs) of patient biopsies. This task is very time-consuming, tedious and subjective.
arxiv