Results 91 to 100 of about 5,422 (196)
Ectopic adrenocorticotropic hormone syndrome (EAS) is a rare condition caused by pancreatic neuroendocrine tumors (p-NETs). The severe hypercortisolemia that characterizes EAS is associated with a poor prognosis and survival.
Shaobo Hu +6 more
doaj +1 more source
Polymyxins are currently used as the last-resort antibiotics against multidrug-resistant Acinetobacter baumannii. As resistance to polymyxins emerges in A. baumannii with monotherapy, combination therapy is often the only remaining treatment option.
Thien B. Tran +6 more
doaj +1 more source
Diagnostic approach to a functional adrenal tumour in a Shih-Tzu Poodle mix [PDF]
Hyperadrenocorticism is the excessive production of cortisol by the adrenal cortex. 15-20% of hyperadrenocorticism in dogs may be due to functional adrenal tumour.
Lim, Sue Yee +2 more
core
Histamine inhibits adrenocortical cell proliferation but does not affect steroidogenesis. [PDF]
Histamine (HA) is a neurotransmitter synthesized in most mammalian tissues exclusively by histidine decarboxylase enzyme. Among the plethora of actions mediated by HA, the modulatory effects on steroidogenesis and proliferation in Leydig cells (LCs) have
Mondillo, Carolina +4 more
core +2 more sources
The PI3K/Akt Pathway in Tumors of Endocrine Tissues [PDF]
The phosphatidylinositol 3-kinase (PI3K)/Akt pathway is a key driver in carcinogenesis. Defects in this pathway in human cancer syndromes such as Cowden’s disease and Multiple Endocrine Neoplasia result in tumors of endocrine tissues, highlighting its ...
Hague, Angela, Robbins, Helen Louise
core +2 more sources
A 43-year-old woman with metastatic adrenocortical carcinoma from the left adrenal gland for which she was prescribed therapeutic mitotane was found to have grade 4 immune-mediated liver injury caused by checkpoint inhibitors that was unresponsive to ...
Christopher Pham +8 more
doaj +1 more source
A 33 year old African American male was admitted to the University of Missouri I.M. Service, referred from a community hospital for uncontrolled hypertension.
Emerson, Abigail, Lancey, Robert
core
Swollen limbs and bone pain : a case report [PDF]
A 50 year old man presented with peripheral oedema, abdominal distension and a pulmonary opacity on CXR. He subsequently perforated his sigmoid colon as a complication of diverticulitis with pericolic abscess. After colectomy his postoperative period was
Cacciottolo, Joseph M. +2 more
core
Hypogonadism and sexual function in men affected by adrenocortical carcinoma under mitotane therapy
PurposeAdrenocortical carcinoma (ACC) is a rare and aggressive tumor. ACC male patients under adjuvant mitotane therapy (AMT) frequently develop hypogonadism, however sexual function has never been assessed in this setting.
Letizia Canu +35 more
doaj +1 more source

