Results 91 to 100 of about 5,422 (196)

Effect of mitotane in patients with ectopic adrenocorticotropic hormone syndrome caused by advanced pancreatic neuroendocrine tumors: a case series and review of the literature

open access: yesJournal of International Medical Research
Ectopic adrenocorticotropic hormone syndrome (EAS) is a rare condition caused by pancreatic neuroendocrine tumors (p-NETs). The severe hypercortisolemia that characterizes EAS is associated with a poor prognosis and survival.
Shaobo Hu   +6 more
doaj   +1 more source

Synergistic Killing of Polymyxin B in Combination With the Antineoplastic Drug Mitotane Against Polymyxin-Susceptible and -Resistant Acinetobacter baumannii: A Metabolomic Study

open access: yesFrontiers in Pharmacology, 2018
Polymyxins are currently used as the last-resort antibiotics against multidrug-resistant Acinetobacter baumannii. As resistance to polymyxins emerges in A. baumannii with monotherapy, combination therapy is often the only remaining treatment option.
Thien B. Tran   +6 more
doaj   +1 more source

Diagnostic approach to a functional adrenal tumour in a Shih-Tzu Poodle mix [PDF]

open access: yes, 2016
Hyperadrenocorticism is the excessive production of cortisol by the adrenal cortex. 15-20% of hyperadrenocorticism in dogs may be due to functional adrenal tumour.
Lim, Sue Yee   +2 more
core  

Histamine inhibits adrenocortical cell proliferation but does not affect steroidogenesis. [PDF]

open access: yes, 2014
Histamine (HA) is a neurotransmitter synthesized in most mammalian tissues exclusively by histidine decarboxylase enzyme. Among the plethora of actions mediated by HA, the modulatory effects on steroidogenesis and proliferation in Leydig cells (LCs) have
Mondillo, Carolina   +4 more
core   +2 more sources

The PI3K/Akt Pathway in Tumors of Endocrine Tissues [PDF]

open access: yes, 2016
The phosphatidylinositol 3-kinase (PI3K)/Akt pathway is a key driver in carcinogenesis. Defects in this pathway in human cancer syndromes such as Cowden’s disease and Multiple Endocrine Neoplasia result in tumors of endocrine tissues, highlighting its ...
Hague, Angela, Robbins, Helen Louise
core   +2 more sources

Immune-Mediated Liver Injury From Checkpoint Inhibitors Requiring Supratherapeutic Corticosteroid and Mycophenolate Treatment

open access: yesAnnals of Internal Medicine: Clinical Cases
A 43-year-old woman with metastatic adrenocortical carcinoma from the left adrenal gland for which she was prescribed therapeutic mitotane was found to have grade 4 immune-mediated liver injury caused by checkpoint inhibitors that was unresponsive to ...
Christopher Pham   +8 more
doaj   +1 more source

Issue Information

open access: yes
IJU Case Reports, Volume 8, Issue 5, Page 437-440, September 2025.
wiley   +1 more source

Case of the month [PDF]

open access: yes, 2009
A 33 year old African American male was admitted to the University of Missouri I.M. Service, referred from a community hospital for uncontrolled hypertension.
Emerson, Abigail, Lancey, Robert
core  

Swollen limbs and bone pain : a case report [PDF]

open access: yes, 2005
A 50 year old man presented with peripheral oedema, abdominal distension and a pulmonary opacity on CXR. He subsequently perforated his sigmoid colon as a complication of diverticulitis with pericolic abscess. After colectomy his postoperative period was
Cacciottolo, Joseph M.   +2 more
core  

Hypogonadism and sexual function in men affected by adrenocortical carcinoma under mitotane therapy

open access: yesFrontiers in Endocrinology
PurposeAdrenocortical carcinoma (ACC) is a rare and aggressive tumor. ACC male patients under adjuvant mitotane therapy (AMT) frequently develop hypogonadism, however sexual function has never been assessed in this setting.
Letizia Canu   +35 more
doaj   +1 more source

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