Results 81 to 90 of about 5,422 (196)

Access to Substituted 1,1‐Diarylalkanes by Friedel–Crafts Benzylations Mediated by FeCl3‐based Deep Eutectic Solvents

open access: yesChemSusChem, Volume 18, Issue 2, January 14, 2025.
A Friedel–Crafts reaction mediated by an Fe(III)‐based Deep Eutectic Solvent (DES) is described. This methodology allows the use of a wide variety of benzylation agents (styrenes, alcohols, ethers, acetates, and chlorides), is suitable for deactivated substrates, enables direct isolation of reaction products, easily adapts to multigram scales, and ...
Marina Ramos‐Martín   +2 more
wiley   +1 more source

Evaluation of 9-cis retinoic acid and mitotane as antitumoral agents in an adrenocortical xenograft model [PDF]

open access: yes, 2015
The available drug treatment options for adrenocortical carcinoma (ACC) are limited. In our previous studies, the in vitro activity of 9-cis retinoic acid (9-cisRA) on adrenocortical NCI-H295R cells was shown along with its antitumoral effects in a small
Baghy, Kornélia   +12 more
core  

novel insights into the genetics and pathophysiology of adrenocortical tumors [PDF]

open access: yes, 2015
International audienceAdrenocortical tumors (ACTs) are typically unilateral and can be classified as benign adrenocortical adenomas (ACAs) or malignant adrenocortical cancers (ACCs).
Drougat, Ludivine   +3 more
core   +7 more sources

Advanced adrenocortical carcinoma successfully treated with gemcitabine plus capecitabine as second‐line chemotherapy

open access: yesIJU Case Reports, 2020
Introduction Adrenocortical carcinoma is a rare malignant tumor with an unfavorable prognosis in the advanced stage for which second‐/third‐line chemotherapy is not well established.
Akinaru Yamamoto   +8 more
doaj   +1 more source

Evaluation of cortisol precursors for the diagnosis of pituitary-dependent hypercortisolism in dogs [PDF]

open access: yes, 2008
The serum concentrations of cortisol, 17alpha-hydroxypregnenolone, 17alpha-hydroxyprogesterone, 21-deoxycortisol and 11-deoxycortisol were measured in 19 healthy dogs, 15 dogs with pituitary-dependent hypercortisolism (pdh) and eight dogs with other ...
Boretti, Felicitas S   +4 more
core   +1 more source

Keganasan Kelenjar Adrenal [PDF]

open access: yes, 2009
Kelenjar adrenal merupakan organ bilateral retroperitoneal pada kutub atas masing-masing ginjal dengan berat empat gram. Kelenjar ini terdiri dari dua bagian, yaitu korteks dan medula, dalam satu kesatuan jaringan berkapsul dan berfungsi menghasilkan ...
Kastomo, D. R. (Dukut)
core  

Cushing’s disease [PDF]

open access: yes, 2012
Cushing’s disease, or pituitary ACTH dependent Cushing’s syndrome, is a rare disease responsible for increased morbidity and mortality. Signs and symptoms of hypercortisolism are usually non specific: obesity, signs of protein wasting, increased blood ...
Bernard Conte-Devolx   +3 more
core   +1 more source

Effect of Intravenous or Perivascular Injection of Synthetic Adrenocorticotropic Hormone on Stimulation Test Results in Dogs. [PDF]

open access: yes, 2017
BackgroundStandard protocols for adrenocorticotropic hormone (ACTH) stimulation testing (ACTHst) often involve intravenous (IV) injection of corticotropin.
Cohen, TA   +3 more
core   +1 more source

rac-2-[(2-Chlorophenyl)(4-chlorophenyl)methyl]-1,3-dioxolane

open access: yesActa Crystallographica Section E, 2012
The title compound, C16H14Cl2O2, is a chiral mitotane derivative that contains a dioxolane ring and crystallizes from methanol as a racemic mixture.
Daniela F. Maluf   +3 more
doaj   +1 more source

Clonal Composition of Human Adrenocortical Neoplasms [PDF]

open access: yes, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms are still not understood. Tumor formation may be the result of spontaneous transformation of adrenocortical cells by somatic mutations.
Abdelhamid, S.   +7 more
core  

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