Results 81 to 90 of about 5,422 (196)
A Friedel–Crafts reaction mediated by an Fe(III)‐based Deep Eutectic Solvent (DES) is described. This methodology allows the use of a wide variety of benzylation agents (styrenes, alcohols, ethers, acetates, and chlorides), is suitable for deactivated substrates, enables direct isolation of reaction products, easily adapts to multigram scales, and ...
Marina Ramos‐Martín +2 more
wiley +1 more source
Evaluation of 9-cis retinoic acid and mitotane as antitumoral agents in an adrenocortical xenograft model [PDF]
The available drug treatment options for adrenocortical carcinoma (ACC) are limited. In our previous studies, the in vitro activity of 9-cis retinoic acid (9-cisRA) on adrenocortical NCI-H295R cells was shown along with its antitumoral effects in a small
Baghy, Kornélia +12 more
core
novel insights into the genetics and pathophysiology of adrenocortical tumors [PDF]
International audienceAdrenocortical tumors (ACTs) are typically unilateral and can be classified as benign adrenocortical adenomas (ACAs) or malignant adrenocortical cancers (ACCs).
Drougat, Ludivine +3 more
core +7 more sources
Introduction Adrenocortical carcinoma is a rare malignant tumor with an unfavorable prognosis in the advanced stage for which second‐/third‐line chemotherapy is not well established.
Akinaru Yamamoto +8 more
doaj +1 more source
Evaluation of cortisol precursors for the diagnosis of pituitary-dependent hypercortisolism in dogs [PDF]
The serum concentrations of cortisol, 17alpha-hydroxypregnenolone, 17alpha-hydroxyprogesterone, 21-deoxycortisol and 11-deoxycortisol were measured in 19 healthy dogs, 15 dogs with pituitary-dependent hypercortisolism (pdh) and eight dogs with other ...
Boretti, Felicitas S +4 more
core +1 more source
Keganasan Kelenjar Adrenal [PDF]
Kelenjar adrenal merupakan organ bilateral retroperitoneal pada kutub atas masing-masing ginjal dengan berat empat gram. Kelenjar ini terdiri dari dua bagian, yaitu korteks dan medula, dalam satu kesatuan jaringan berkapsul dan berfungsi menghasilkan ...
Kastomo, D. R. (Dukut)
core
Cushing’s disease, or pituitary ACTH dependent Cushing’s syndrome, is a rare disease responsible for increased morbidity and mortality. Signs and symptoms of hypercortisolism are usually non specific: obesity, signs of protein wasting, increased blood ...
Bernard Conte-Devolx +3 more
core +1 more source
Effect of Intravenous or Perivascular Injection of Synthetic Adrenocorticotropic Hormone on Stimulation Test Results in Dogs. [PDF]
BackgroundStandard protocols for adrenocorticotropic hormone (ACTH) stimulation testing (ACTHst) often involve intravenous (IV) injection of corticotropin.
Cohen, TA +3 more
core +1 more source
rac-2-[(2-Chlorophenyl)(4-chlorophenyl)methyl]-1,3-dioxolane
The title compound, C16H14Cl2O2, is a chiral mitotane derivative that contains a dioxolane ring and crystallizes from methanol as a racemic mixture.
Daniela F. Maluf +3 more
doaj +1 more source
Clonal Composition of Human Adrenocortical Neoplasms [PDF]
The mechanisms of tumorigenesis of adrenocortical neoplasms are still not understood. Tumor formation may be the result of spontaneous transformation of adrenocortical cells by somatic mutations.
Abdelhamid, S. +7 more
core

