Results 91 to 100 of about 55,808 (294)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Performance analysis comparison between non mixed-criticality and mixed-criticality system in microcontroller

Indonesian Journal of Electrical Engineering and Computer Science, 2019
<span>Nowadays, implementation of real-time embedded system or safety-critical in a real-time system is significant within emerging technologies because the system involves many aspects such as safety and task execution without missing deadlines. The main cause of implementation is to avoid catastrophic loss.
Siti Nurhafizza Maidin, Noor Azurati Ahmad, Kamilia Kamardin, Shamsul Sahibuddin, Syahrizal Fadhlie Sabri   +4 more
openaire   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Critical phenomena in one dimension from a Bethe ansatz perspective

, 2014
This article briefly reviews recent theoretical developments in quantum critical phenomena in one-dimensional (1D) integrable quantum gases of cold atoms.
Guan, Xiwen
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Study on Influence of Nitric Acid Concentration on Criticality Safety

Yuanzineng kexue jishu
The nuclear criticality safety issue in spent fuel reprocessing facilities is closely related to the main process and is almost equally important. It is closely related to the design and operation of reprocessing facilities.
WANG Fan, ZHU Qingfu, XIA Zhaodong, ZHOU Qi, CHEN Xiaoxian, CHENG Yuting, LIANG Shuhong, LI Hang, ZHANG Zhifeng, LIU Yang
doaj   +1 more source

Improvement to Semi-Partitioned Cyclic Executives for Mixed-Criticality Scheduling on Multiprocessor Platforms

IEEE Access, 2020
This paper focuses on semi-partitioned cyclic executives for mixed-criticality multiprocessor systems in the case of which a job can be split and execute on different processors, this strategy incorporates most of the advantages of the fully partitioned ...
Fengxiang Zhang
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Robust Communication Design in RIS-Assisted THz Channels

IEEE Open Journal of the Communications Society
Terahertz (THz) communication offers the necessary bandwidth to meet the high data rate demands of next-generation wireless systems. However, it faces significant challenges, including severe path loss, dynamic blockages, and beam misalignment, which ...
Yasemin Karacora, Adam Umra, Aydin Sezgin   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source