Results 91 to 100 of about 219,022 (300)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Robust Communication Design in RIS-Assisted THz Channels
IEEE Open Journal of the Communications SocietyTerahertz (THz) communication offers the necessary bandwidth to meet the high data rate demands of next-generation wireless systems. However, it faces significant challenges, including severe path loss, dynamic blockages, and beam misalignment, which ...
Yasemin Karacora +2 more
doaj +1 more source
Energy efficient partition allocation in mixed-criticality systems.
PLoS ONE, 2019 This paper addresses the problem of energy management of mixed criticality applications in a multi-core partitioned architecture. Instead of focusing on new scheduling algorithms to adjust frequency in order to save energy, we propose a partition to CPU ...
Ana Guasque +3 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
, 2013 In mixed-criticality systems, applications with different levels of criticality are integrated on the same computational platform. Without a proper isolation of the different applications of such a mixed-criticality system certification gets ...
Cilku, Bekim, Puschner, Peter
core
Criticality-aware Design Space Exploration for Mixed-Criticality Embedded Systems
, 2018 This work focuses on Design Space Exploration for embedded systems based on heterogeneous parallel architectures and subjected to mixed-criticality constraints.
Giacomo Valente +8 more
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
ESOMICS: ML-Based Timing Behavior Analysis for Efficient Mixed-Criticality System Design
IEEE AccessIn Mixed-Criticality (MC) systems, due to encountering multiple Worst-Case Execution Times (WCETs) for each task corresponding to the system operation modes, estimating appropriate WCETs for tasks in lower-criticality (LO) modes is essential to improve ...
Vikash Kumar +2 more
doaj +1 more source
IEEE Access, 2019 The Internet of Things (IoT) and Industrial Internet of Things (IIoT) trends, where high connectivity is envisioned, are giving rise to new applications, services, and paradigms, such as smart cities.
Imanol Mugarza +3 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source