Results 71 to 80 of about 5,633 (293)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Accurate Strategy for Mixed Criticality Scheduling [PDF]
, 2020 In mixed criticality systems, functionalities with different criticalities share the same execution platform. The goal of a mixed criticality scheduling algorithm is to ensure a safe execution of the highest criticality tasks while using efficiently the execution platform.
openaire +2 more sources
A Survey of Research into Mixed Criticality Systems [PDF]
ACM Computing Surveys, 2017 This survey covers research into mixed criticality systems that has been published since Vestal’s seminal paper in 2007, up until the end of 2016. The survey is organised along the lines of the major research areas within this topic. These include single processor analysis (including fixed priority and Earliest Deadline First (EDF) scheduling, shared ...
Burns, Alan, Davis, Robert Ian
openaire +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Modeling Mixed-critical Systems in Real-time BIP
, 2013 International audienceThe proliferation of multi- and manycores creates an important design problem: the design and verification for mixed-criticality constraints in timing and safety, taking into account the resource sharing and hardware faults.
Bozga, Marius +3 more
core +1 more source
Component-Based Mixed-Criticality Real-Time Scheduling on a Single Processor System
IEEE AccessThis paper focuses on a two-level hierarchical system with dual-criticality components scheduled on a single processor. To address the independent scheduling of mixed-criticality (MC) components using fixed-priority (FP) servers, we introduce the mixed ...
Dandi Ma
doaj +1 more source
A toolset for the development of mixed-criticality partitioned systems [PDF]
, 2014 The development of mixed-criticality virtualized multi-core systems poses new challenges that are being subject of active research work. There is an additional complexity: it is now required to identify a set of partitions, and allocate applications to ...
Salazar Marsá, José Emilio +2 more
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Extending Mixed Criticality Scheduling [PDF]
, 2013 The capability of hardware is constantly developing in capacity, speed and efficiency. This development has sparked industrial and academic interest in how best to utilise the increased capability. It is now possible to integrate many systems that in the
Fleming, Thomas
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source