Results 81 to 90 of about 7,760,731 (337)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Utilization-Based Safety Aware Scheduling of Mixed-Criticality Real-Time System With Gradual Performance Degradation

open access: yesIEEE Access
Mixed-criticality (MC) systems have become indispensable in managing diverse tasks within unified computational environments, particularly in complex embedded systems like those in the automotive and avionics industries.
Xinyang Dong, Wang Yi
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Analysis-Runtime Co-Design for EDF-VD-Based Mixed-Criticality Scheduling: Improving Completion Rates of Low-Criticality Jobs

open access: yesIEEE Access
In this paper, we explore mixed criticality systems, where traditional approaches often adopt a pessimistic stance in managing low-criticality tasks, focusing primarily on ensuring the timely completion of high-criticality tasks. We optimized the “
Zhenkai Hao
doaj   +1 more source

Collective behavior and evolutionary games - An introduction [PDF]

open access: yes, 2013
This is an introduction to the special issue titled "Collective behavior and evolutionary games" that is in the making at Chaos, Solitons & Fractals. The term collective behavior covers many different phenomena in nature and society. From bird flocks and
Grigolini, Paolo, Perc, Matjaz
core   +2 more sources

Mixed-Criticality Industrial Wireless Networks

open access: yes, 2023
This open access book introduces how to manage important tasks in industrial wireless networks. Important tasks must be completed on time and with guaranteed quality; that is the consensus reached by system designers and users. However, for too long, important tasks have often been given unnecessary urgency, and people intuitively believe that ...
Jin, Xi   +3 more
openaire   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Component-Based Mixed-Criticality Real-Time Scheduling on a Single Processor System

open access: yesIEEE Access
This paper focuses on a two-level hierarchical system with dual-criticality components scheduled on a single processor. To address the independent scheduling of mixed-criticality (MC) components using fixed-priority (FP) servers, we introduce the mixed ...
Dandi Ma
doaj   +1 more source

Multiprocessor Scheduling of Precedence-constrained Mixed-Critical Jobs

open access: yes, 2015
International audienceThe real-time system design targeting multiprocessor platforms leads to two important complications in real-time scheduling. First, to ensure deterministic processing by communicating tasks the scheduling has to consider precedence ...
Bensalem, Saddek   +3 more
core   +3 more sources

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