Results 101 to 110 of about 5,633 (293)

Towards Temporal and Spatial Isolation in Memory Hierarchies for Mixed-Criticality Systems with Hypervisors

open access: yes, 2013
In mixed-criticality systems, applications with different levels of criticality are integrated on the same computational platform. Without a proper isolation of the different applications of such a mixed-criticality system certification gets ...
Cilku, Bekim, Puschner, Peter
core  

Energy Efficient Mapping of Mixed Criticality Applications on Unrelated Heterogeneous Multicore Platforms

open access: yes
11th IEEE International Symposium on Industrial Embedded Systems (SIES 2016). 23 to 25, May, 2016. Krakow, Poland.Heterogeneous multicore platforms are becoming an attractive choice to deploy mixed criticality systems demanding diverse computational ...
Masson, Damien   +2 more
core   +1 more source

Partitioned Multiprocessor Scheduling of Mixed-Criticality Parallel Jobs

open access: yes, 2014
Motivated by the increasing trend in embedded systems towards platform integration, there has been an increasing research interest in scheduling mixed-criticality systems.
Lu, Ying   +7 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Development of Real-Time and Mixed Criticality Distributed Systems through the DDS Standard

open access: yesRevista Iberoamericana de Automática e Informática Industrial RIAI, 2018
The use of distribution middleware facilitates the programming of heterogeneous real-time distributed systems, and it can also facilitate the automatic generation of source code when integrated as a part of a general MDE (Model-Driven Engineering ...
Héctor Pérez Tijero   +1 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Hypervisor-Based Multicore Feedback Control of Mixed-Criticality Systems

open access: yesIEEE Access, 2018
One of the most promising approaches to mixed-criticality systems is the use of multi-core execution platforms based on a hypervisor. Several successful EU Projects are based on this approach and have overcome some of the difficulties that this approach ...
Alfons Crespo   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Experimental Evaluation of SAFEPOWER Architecture for Safe and Power-Efficient Mixed-Criticality Systems

open access: yesJournal of Low Power Electronics and Applications, 2019
With the ever-increasing industrial demand for bigger, faster and more efficient systems, a growing number of cores is integrated on a single chip. Additionally, their performance is further maximized by simultaneously executing as many processes as ...
Maher Fakih   +18 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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