Results 61 to 70 of about 10,725,281 (282)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Towards the Design of Certifiable Mixed-criticality Systems

open access: yes2010 16th IEEE Real-Time and Embedded Technology and Applications Symposium, 2010
Many safety-critical embedded systems are subject to certification requirements; some systems may be required to meet multiple sets of certification requirements, from different certification authorities. Certification requirements in such "mixed-criticality" systems give rise to some interesting scheduling problems, that cannot be satisfactorily ...
S.K. Baruah (Sanjoy)   +2 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Criticality-Aware EDF Scheduling for Constrained-Deadline Imprecise Mixed-Criticality Systems

open access: yes, 2023
EDF-VD first focuses on the classic mixed-criticality task model in which all low criticality (LO) tasks are abandoned in the high criticality mode, which is an effective dynamic priority scheduling algorithm for mixed-criticality systems.
Yi-Wen Zhang   +7 more
core   +1 more source

IMC-PALM: Enhancing Survivability of Imprecise Mixed-Criticality Cyber-Physical Systems via Mode-Balanced Partitioning and Adaptive Task Migration

open access: yesSystems
Complex cyber-physical systems in the automotive and avionics domains increasingly consolidate safety-critical and non-critical functions onto shared multicore platforms.
Jaewoo Lee
doaj   +1 more source

Mixed Criticality Scheduling for Industrial Wireless Sensor Networks

open access: yesSensors, 2016
Wireless sensor networks (WSNs) have been widely used in industrial systems. Their real-time performance and reliability are fundamental to industrial production. Many works have studied the two aspects, but only focus on single criticality WSNs.
Xi Jin   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Response time analysis of multiframe mixed-criticality systems

open access: yes, 2019
The well-known model of Vestal aims to avoid excessive pessimism in the quantification of the processing requirements of mixed-criticality systems, while still guaranteeing the timeliness of higher-criticality functions.
Souto, P.F.   +5 more
core   +2 more sources

Analysis-Runtime Co-Design for EDF-VD-Based Mixed-Criticality Scheduling: Improving Completion Rates of Low-Criticality Jobs

open access: yesIEEE Access
In this paper, we explore mixed criticality systems, where traditional approaches often adopt a pessimistic stance in managing low-criticality tasks, focusing primarily on ensuring the timely completion of high-criticality tasks. We optimized the “
Zhenkai Hao
doaj   +1 more source

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