Results 61 to 70 of about 2,740 (260)
IEEE AccessIn this paper, we explore mixed criticality systems, where traditional approaches often adopt a pessimistic stance in managing low-criticality tasks, focusing primarily on ensuring the timely completion of high-criticality tasks. We optimized the “
Zhenkai Hao
doaj +1 more source
Towards the Design of Certifiable Mixed-criticality Systems
2010 16th IEEE Real-Time and Embedded Technology and Applications Symposium, 2010 Many safety-critical embedded systems are subject to certification requirements; some systems may be required to meet multiple sets of certification requirements, from different certification authorities. Certification requirements in such "mixed-criticality" systems give rise to some interesting scheduling problems, that cannot be satisfactorily ...
S.K. Baruah (Sanjoy) +2 more
openaire +2 more sources
Response-Time Analysis for Mixed Criticality Systems [PDF]
2011 IEEE 32nd Real-Time Systems Symposium, 2011 Many safety-critical embedded systems are subject to certification requirements. However, only a subset of the functionality of the system may be safety-critical and hence subject to certification, the rest of the functionality is non safety-critical and does not need to be certified, or is certified to a lower level.
Sanjoy K. Baruah +2 more
openaire +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Mixed Criticality Multicore Compositional Framework
IEEE AccessIn the field of real-time systems, component-based models for mixed criticality systems (MCS) on multicore platform are gaining significant attention of the researchers from the recent past.
Amjad Ali +5 more
doaj +1 more source