Results 81 to 90 of about 431,056 (348)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Hollow Y zeolite single crystals: synthesis, characterization and activity in the hydroisomerization of n-hexadecane

Oil & Gas Science and Technology, 2019
Hollow Y zeolite single crystals have been obtained from a conventional NaY zeolite following a three-step process involving a severe dealumination of the zeolite with silicon tetrachloride (step #1), followed by an acid washing under mild conditions ...
Pagis Céline, Bouchy Christophe, Dodin Mathias, Martinez Franco Raquel, Farrusseng David, Tuel Alain   +5 more
doaj   +1 more source

Mixed-parity superconductivity in centrosymmetric crystals

, 2004
A weak-coupling formalism for superconducting states possessing both singlet (even parity) and triplet (odd parity) components of the order parameter in centrosymmetric crystals is developed.
A.F. Volkov, A.J. Leggett, E.D. Bauer, E.E.M. Chia, E.I. Blount, F.S. Bergeret, G.E. Volovik, H. Shimahara, H. Sugawara, I. A. Sergienko, K. Izawa, K. Ueda, L.P. Gor’kov, L.P. Gor’kov, M. Sigrist, M. Sigrist, M.R. Norman, N. Takeda, N.A. Frederick, R. Vollmer, R.S. Hayano, S. Matsuo, V.P. Mineev, Y. Aoki   +23 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Photoinduced charge separation in Q1D heterojunction materials: Evidence for electron-hole pair separation in mixed-halide $MX$ solids

, 1992
Resonance Raman experiments on doped and photoexcited single crystals of mixed-halide $MX$ complexes ($M$=Pt; $X$=Cl,Br) clearly indicate charge separation: electron polarons preferentially locate on PtBr segments while hole polarons are trapped within ...
, A R Bishop, A Saxena, B I Swanson, Batistic I, Donohoe R J, Gammel J T, Huang X Z, Huckett S C, J Tinka Gammel, Keller H J, Kurita S, L A Worl, S C Huckett, Toriumi K, Weber-Milbrodt S M   +15 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Physical properties of High Arctic tropospheric particles during winter [PDF]

Atmospheric Chemistry and Physics, 2009
A climatology of particle scattering properties in the wintertime High Arctic troposphere, including vertical distributions and effective radii, is presented.
L. Bourdages, T. J. Duck, G. Lesins, J. R. Drummond, E. W. Eloranta   +4 more
doaj  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

THE FORMATION MECHANISM OF ASSEMBLED COMPLEXES BRIDGED BY1,3–BIS(4–PYRIDYL)PROPANE [PDF]

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2016
Several types of crystals having different color appeared in the synthesis of assembled complex of mixed crystals with three metals. [H2(bpp)][M(NCS)4] changed to 1D chain polymer (M(NCS)2(bpp)) by releasing HNCS from the cation and anion in a reaction ...
Haruka Dote, Hiroki Yasuhara, Satoru Nakashima   +2 more
doaj  

Growth of mixed K2NixCo(1−x)(SO4)2 · 6H2O crystals for large supercooling without spontaneous crystallization in solution

Materials Research Express, 2019
A scheme for growing mixed K _2 Ni _x Co _(1−x) (SO _4 ) _2  · 6H _2 O (KCNSH) single crystals under conditions of supercooling at 5 °C–10 °C without spontaneous crystallization in solution for more than a month has been proposed and implemented.
Andrei A Zhokhov, Vladimir M Masalov, Elena B Rudneva, Vera L Manomenova, Natalia A Vasilyeva, Nadezhda S Sukhinina, Alexey E Voloshin, Gennadi A Emelchenko   +7 more
doaj   +1 more source