Results 51 to 60 of about 13,961,135 (286)

Sample Size Requirements for Applying Mixed Polytomous Item Response Models: Results of a Monte Carlo Simulation Study

open access: yesFrontiers in Psychology, 2019
Mixture models of item response theory (IRT) can be used to detect inappropriate category use. Data collected by panel surveys where attitudes and traits are typically assessed by short scales with many response categories are prone to response styles ...
Tanja Kutscher   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A Systematic Review of Chinese Character Size Tests From 1930 to 2021

open access: yesSAGE Open, 2023
Chinese character size is the number of characters that a person can recognize and has been well documented as a critical measure of Chinese literacy. A variety of Chinese character size tests have been developed since the 1930s.
Haiwei Zhang   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Assessing the Impact of Characteristics of the Test, Common-items, and Examinees on the Preservation of Equity Properties in Mixed-format Test Equating [PDF]

open access: yes, 2014
Preservation of equity properties was examined using four equating methods - IRT True Score, IRT Observed Score, Frequency Estimation, and Chained Equipercentile - in a mixed-format test under a common-item nonequivalent groups (CINEG) design.
Wolf, Raffaela
core  

Forced Choice Assessment of Work Related Maladaptive Personality Traits: Preliminary Evidence from an Application of Thurstonian Item Response Modeling [PDF]

open access: yes, 2016
This article describes an investigation of whether Thurstonian item response modeling is a viable method for assessment of maladaptive traits. Forced-choice responses from 420 working adults to a broad-range personality inventory assessing six ...
Cooper, Andrew J.   +3 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

An Item Response Theory Approach to the Maintenance of Standards in Public Examinations in England [PDF]

open access: yes, 2011
Every year outcomes from public examinations in the UK rise: politicians congratulate pupils on their hard earned achievement; the media questions whether this achievement is real; those responsible for administrating the examinations defend their ...
WHEADON, CHRISTOPHER,BRIAN   +1 more
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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