Results 101 to 110 of about 32,627,451 (335)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Cleaning the palate and tongue without nausea: a mixed methods study exploring the appropriate depth and direction of oral care [PDF]

, 2021
Yang Cheng, Zhou Yu-feng, Yaping Ding, Ying Xing, Enfang Shan, Hang Sun   +5 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Mixed Methods in Finance Research

International Journal of Qualitative Methods, 2018
The purpose of this study is to uncover the rationale (why) and the types of designs (what) for application of mixed method approaches in finance research using a systematic literature review approach.
N. J. Dewasiri, Y. K. B. Weerakoon, A. A. Azeez   +2 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

The Intersection of Work and Home Challenges Faced by Physician Mothers During the Coronavirus Disease 2019 Pandemic: A Mixed-Methods Analysis

, 2021
Meghan C. Halley, Kusum S. Mathews, Lisa C. Diamond, Elizabeth Linos, Urmimala Sarkar, Christina Mangurian, Hala Sabry, Monika K. Goyal, Kristan Olazo, Emily G. Miller, Reshma Jagsi, Eleni Linos, Eleni Linos, Eleni Linos   +13 more
openalex   +2 more sources

Disordered eating & body image of current and former athletes in a pandemic; a convergent mixed methods study - What can we learn from COVID-19 to support athletes through transitions? [PDF]

, 2021
Georgina Buckley, Linden Elizabeth Hall, Annie‐Claude M. Lassemillante, Regina Belski   +3 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

How VA Whole Health Coaching Can Impact Veterans’ Health and Quality of Life: A Mixed-Methods Pilot Program Evaluation

, 2021
Natalie Purcell, Kara Zamora, Daniel Bertenthal, Linda Abadjian, Jennifer Tighe, Karen H. Seal   +5 more
openalex   +1 more source

Co-designing a Lifestyle-Focused Text Message Intervention for Women After Breast Cancer Treatment: Mixed Methods Study [PDF]

, 2021
Anna Singleton, Rebecca Raeside, Stephanie R. Partridge, Molly Hayes, Katherine Maka, Karice Hyun, Aravinda Thiagalingam, Clara K Chow, Kerry A. Sherman, Elisabeth Elder, Julie Redfern   +10 more
openalex   +1 more source