Results 61 to 70 of about 6,114,735 (276)

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy, Elizabeth L. Seashore, W. Susan Cheng, Shondra Clay, Jessica A. Casas, Jennifer H. Foster   +5 more
wiley   +1 more source

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson, Menna Shamma, Upeka Senanayake, Shaimaa Sahmoud, Kathleen Duffin, Victoria Howard, David King, Ayesha Fathani, Blanche Lumb, Andrei Pobischan, Irum Latif Memon, Monzir Ahmed, Rhian Thomas, Gerard Millen, Yasmeen Alomari, Sucheta Vaidya, Lynley V. Marshall, Sally L. George, Ramya Ramanujachar, Juliet Gray, Paola Angelini   +20 more
wiley   +1 more source

Don't Blame the Software: Using Qualitative Data Analysis Software Successfully in Doctoral Research

Forum: Qualitative Social Research, 2016
In this article, we explore the learning experiences of doctoral candidates as they use qualitative data analysis software (QDAS). Of particular interest is the process of adopting technology during the development of research methodology.
Michelle Salmona, Dan Kaczynski
doaj  

A Pilot Study on the Freelisting Method Among Adolescents with Chronic Musculoskeletal Pain: Feasibility, Acceptability and Study Findings

Children
Background/Objectives: To assess the feasibility and acceptability of freelisting for adolescents with chronic musculoskeletal pain (CMP) and use freelisting to identify how adolescents with CMP cope with pain.
Sabrina Gmuca, Dori Abel, Mackenzie McGill, Daneka Stryker, Eda Akpek, Whitney Eriksen, Pamela F. Weiss, Peter F. Cronholm   +7 more
doaj   +1 more source

Generating metainferences in mixed methods research: A worked example in convergent mixed methods designs

Methodological Innovations, 2023
Metainferences, or the insights derived from integrating quantitative and qualitative inferences at the end of a study, are crucial for achieving added value and synergy in mixed methods research.
Ahtisham Younas, Sergi Fàbregues, John W Creswell   +2 more
doaj   +1 more source

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig, Sophie Jessop, Jordan R. Hansford, Hien Le, Matthew O'Connor, Peter Gorayski, Andrew Cunningham, Amanda Hutchinson, Victoria Bedford, Eva Bezak, Nayana Parange, Kelly Skelton, Timothy Price, Michala Short   +13 more
wiley   +1 more source

Barriers to and facilitators of physical activity in pediatric pulmonary hypertension

Pulmonary Circulation
Therapeutic exercise has not been widely adopted in pediatric pulmonary hypertension (PH), despite adult data supporting its safety and efficacy. While physical limitations may prevent children with PH from participating in physical activity, other ...
Catherine M. Avitabile, Caroline O'Brien, Divya Dureja, Dana Albizem, Jena Mota, Melissa Xanthopoulos, Babette S. Zemel, Peter F. Cronholm   +7 more
doaj   +1 more source

Development and Validation of a Circumplex-Based Affective-State Scale for First-Year Engineering Students

Education Sciences
Despite growing awareness of the emotional challenges faced by engineering students and their impact on academic performance and retention, the field lacks validated tools to systematically assess affective states in theoretically grounded ways.
Gibin Mannathikulathil Raju, Cedrick A. K. Kwuimy, Youn Seon Lim   +2 more
doaj   +1 more source

Factors Influencing Adherence to Antiretroviral Treatment in Nepal: A Mixed-Methods Study [PDF]

, 2012
Background Antiretroviral therapy (ART) is a lifesaver for individual patients treated for Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS).
Freeman, Jennifer, Randall, Julian, Simkhada, Padam, van Teijlingen, Edwin, Wasti, Sharada Prasad   +4 more
core   +5 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source