Results 71 to 80 of about 15,892,169 (298)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

NCRM podcast: The 'Thing-ness' problem of mixed methods research

open access: yes, 2014
Is mixed methods research a turbulent environment and is innovation being stifled by an overly tightly bound concept of what it is? Sharlene Hesse-Biber, professor in the Sociology Department of Boston College thinks so.
Hesse-Biber, Sharlene
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The Application of a Multiphase Triangulation Approach to Mixed Methods: The Research of an Aspiring School Principal Development Program

open access: yes, 2011
Mixed methods research has emerged as a credible alternative to unitary research approaches. The authors show how a combination of a triangulation convergence model with a triangulation multilevel model was used to research an aspiring school principal ...
Eileen Piggot-Irvine   +3 more
core   +1 more source

Laura Camfield on undertaking cross-national mixed methods research [PDF]

open access: yes, 2023
In this episode of the Methods podcast, host Catherine McDonald talks to Laura Camfield, Professor of Development Research and Evaluation in the School of International Development at the University of East Anglia.
McDonald, Catherine
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Computer-assisted integration of mixed methods data sources and analyses

open access: yes, 2010
New tools within analysis software, developed in response to the growing interest in mixed methods research, facilitate and extend possibilities for working with mixed data types and analysis methods.
Bazeley, Pat (R13373), Pat Bazeley
core   +1 more source

Mixed methods practice in operational research: designs for wicked problems

open access: yes, 2023
In operational research (OR), practitioners model and analyse real-world issues, and support organizational and policy decision-making. Traditionally, they use quantitative methods, such as optimization, simulation, and statistical analysis.
Christie, Jane S.
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Mixed Methods in Suicide Research

open access: yes, 2021
Mixed methods offer a valuable third paradigm in suicide research that can address the limitations of quantitative and qualitative research methods.
Ross, Victoria, Kolves, Kairi
core  

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