Results 111 to 120 of about 15,569,368 (309)

ESTIMATION AND ASYMPTOTIC THEORY FOR A NEW CLASS OF MIXTURE MODELS [PDF]

open access: yes
In this paper a new model of mixture of distributions is proposed, where the mixing structure is determined by a smooth transition tree architecture.
Eduardo Mendes   +2 more
core  

Evaluation of Analysis Approaches for Latent Class Analysis with Auxiliary Linear Growth Model

open access: yesFrontiers in Psychology, 2018
This study investigated the performance of three selected approaches to estimating a two-phase mixture model, where the first phase was a two-class latent class analysis model and the second phase was a linear growth model with four time points.
Akihito Kamata   +3 more
doaj   +1 more source

Classifier Weighted Mixture Models

open access: yesIEEE Signal Processing Letters
This paper proposes an extension of standard mixture stochastic models, by replacing the constant mixture weights with functional weights defined using a classifier. Classifier Weighted Mixtures enable straightforward density evaluation, explicit sampling, and enhanced expressivity in variational estimation problems, without increasing the number of ...
Elouan Argouarc'h   +4 more
openaire   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Model-robust design of mixture experiments

open access: yes, 2020
Optimal designs are often used for constrained mixture experiments because of the irregular design spaces. For these experiments, the number of blends needed to fit standard linear models may be too large when considering second- or third-order terms. We
Byran J. Smucker (8524911)   +1 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

mixtools: An R Package for Analyzing Mixture Models [PDF]

open access: yes
The mixtools package for R provides a set of functions for analyzing a variety of finite mixture models. These functions include both traditional methods, such as EM algorithms for univariate and multivariate normal mixtures, and newer methods that ...
Tatiana Benaglia   +3 more
core  

depmixS4: An R Package for Hidden Markov Models

open access: yesJournal of Statistical Software, 2010
depmixS4 implements a general framework for defining and estimating dependent mixture models in the R programming language. This includes standard Markov models, latent/hidden Markov models, and latent class and finite mixture distribution models.
Ingmar Visser, Maarten Speekenbrink
doaj  

Effects of fracture network connectivity in coal seams on proppant transport

open access: yesMeitan kexue jishu
The horizontal well staged multi-cluster fracturing used in the development of coalbed methane could jointly form a complex fracture network with cleats in the coal seam.
Jiaxiang XU   +4 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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