Results 131 to 140 of about 15,569,368 (309)

Experimental Channel Modeling of Free-Space Optical Communications Under Atmospheric Turbulence

IEEE Open Journal of the Communications Society
This paper investigates the statistical modeling of atmospheric turbulence-induced fading in free space optical (FSO) communication systems via using a 400-m round-trip retro-reflected urban FSO testbed. Especially, we compare the theoretical FSO channel
Tae-In Oh, Byungju Lim, Young-Chai Ko
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Finite Mixture Models: A Key Tool for Reliability Analyses

Mathematics
As system complexity increases, accurately capturing true system reliability becomes increasingly challenging. Rather than relying on exact analytical solutions, it is often more practical to use approximations based on observed time-to-failure data ...
Marko Nagode, Simon Oman, Jernej Klemenc, Branislav Panić   +3 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Estimating propensity scores with missing covariate data using general location mixture models

, 2009
In many observational studies, researchers estimate causal effects using propensity scores, e.g., by matching or sub-classifying on the scores. Estimation of propensity scores is complicated when some values of the covariates aremissing.
Reiter, Jerome P., Mitra, Robin
core   +2 more sources

Mechanistic insight for T-cell exclusion by cancer-associated fibroblasts in human lung cancer

eLife
The tumor stroma consists mainly of extracellular matrix, fibroblasts, immune cells, and vasculature. Its structure and functions are altered during malignancy: tumor cells transform fibroblasts into cancer-associated fibroblasts, which exhibit ...
Joseph Ackermann, Chiara Bernard, Philemon Sirven, Helene Salmon, Massimiliano Fraldi, Martine D Ben Amar   +5 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Option pricing with asymmetric heteroskedastic normal mixture models [PDF]

This paper uses asymmetric heteroskedastic normal mixture models to fit return data and to price options. The models can be estimated straightforwardly by maximum likelihood, have high statistical fit when used on S&P 500 index return data, and allow for
ROMBOUTS, Jeroen V. K., STENTOFT, Lars
core   +2 more sources

On the Bayesian analysis of species sampling mixture models for density estimation [PDF]

, 2006
The mixture of normals model has been extensively applied to density estimation problems. This paper proposes an alternative parameterisation that naturally leads to new forms of prior distribution.
Griffin, Jim E.
core  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source