Results 151 to 160 of about 46,287 (264)

Tumour MLH1 promoter region methylation testing is an effective prescreen for Lynch Syndrome (HNPCC)

, 2014
Katherine Newton, N M Jorgensen, Andrew J. Wallace, Daniel D. Buchanan, Fiona Lalloo, R F McMahon, James Hill, D. Gareth Evans   +7 more
openalex   +2 more sources

Genetic and Epigenetic Modification of MLH1 [PDF]

The American Journal of Pathology, 2000
Manuel Perucho, Shannon A. Kuismanen, Mari T. Holmberg, Reijo Salovaara   +3 more
openaire   +2 more sources

Two novel germline mutations of MLH1 and investigation of their pathobiology in hereditary non-polyposis colorectal cancer families in China

, 2007
Chao‐Fu Wang, Xiao-Yan Zhou, Tai-Ming Zhang, Ye Xu, San-Jun Cai, Da-Ren Shi   +5 more
openalex   +2 more sources

Elevated mutant frequencies and increased C : G→T : A transitions in Mlh1−/− versus Pms2−/− murine small intestinal epithelial cells [PDF]

, 2001
Agnes Baross-Francis, Naila Makhani, R. Michael Liskay, Frank R. Jirik   +3 more
openalex   +1 more source

MLH1 Negative [PDF]

, 2020
openaire   +1 more source

An in-frame deletion mutation in MLH1 drives Lynch syndrome-associated colorectal cancer

BMC Cancer
Lynch syndrome (LS) is the most common inherited disorder predisposing individuals to colorectal cancer (CRC). It results from germline defects in DNA mismatch repair (MMR) genes, which are critical for maintaining genomic integrity. Here, we demonstrate
Xiaojuan Lin, Ce Bian, Dongni Liang, Lin Li, Qingqing Tang, Qingli Li   +5 more
doaj   +1 more source

Accelerated growth of intestinal tumours after radiation exposure in Mlh1‐knockout mice: evaluation of the late effect of radiation on a mouse model of HNPCC

, 2006
Yutaka Tokairin, Shizuko Kakinuma, Masami Arai, Mayumi Nishimura, Mieko Okamoto, Eisaku Ito, Makoto Akashi, Yoshio Miki, Tatsuyuki Kawano, Takehisa Iwai, Yoshiya Shimada   +10 more
openalex   +2 more sources

MLH1 Gene [PDF]

, 2020
openaire   +1 more source

TDP43 interacts with MLH1 and MSH6 proteins in a DNA damage-inducible manner [PDF]

Vincent E. Provasek, Manohar Kodavati, Brandon Kim, Joy Mitra, Muralidhar L. Hegde   +4 more
openalex   +1 more source

Differential response to immune checkpoint inhibitors in patients with endometrial cancer according to MLH1 hypermethylation vs MLH1 “Lynch-like” mismatch repair gene mutations (1264) [PDF]

, 2023
Matthew A. Powell, Michael Toboni, Sharon Wu, Alex Farrell, Joanne Xiu, Matthew J. Oberley, Rebecca C. Arend, Britt Erickson, Thomas J. Herzog, Premal H. Thaker   +9 more
openalex   +1 more source