Results 1 to 10 of about 186,902 (115)

Role of Matrilysins (MMP-7, MMP-26) and Stromelysins (MMP-3, MMP-10) in Diagnosing Cervical Cancer Patients [PDF]

Biomedicines
Background/Objectives: Detection of cervical lesions is crucial for effective prevention and treatment. Therefore, the search for new diagnostic markers is extremely important.
Ewa Gacuta, Michał Ławicki, Hanna Grabowska, Paweł Ławicki, Monika Kulesza, Aleksandra Kicman, Monika Zajkowska, Piotr Laudański, Sławomir Ławicki   +8 more
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Serum MMP‐3 and its association with central arterial stiffness among young adults is moderated by smoking and BMI [PDF]

Physiological Reports, 2021
Central arterial stiffness is an independent predictor of cardiovascular disease. It is characterized by a marked reduction in the elastin‐collagen ratio of the arterial wall extracellular matrix (ECM), and is largely the result of degradation of various
Nathaniel J. Iannarelli, Adam J. MacNeil, Kylie S. Dempster, Terrance J. Wade, Deborah D. O’Leary   +4 more
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Matrix metalloproteinases (MMP) 3 and 9 as biomarkers of severity in COVID-19 patients [PDF]

Scientific Reports, 2022
The molecular basis of the wide clinical heterogeneity of Coronavirus disease 2019 (COVID-19) is still unknown. Matrix metalloproteinases (MMPs) may have a role in the lung damage and regeneration that occur in severe patients.
Monica Gelzo, Sara Cacciapuoti, Biagio Pinchera, Annunziata De Rosa, Gustavo Cernera, Filippo Scialò, Marika Comegna, Mauro Mormile, Gabriella Fabbrocini, Roberto Parrella, Gaetano Corso, Ivan Gentile, Giuseppe Castaldo   +12 more
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Berberine inhibits RA-FLS cell proliferation and adhesion by regulating RAS/MAPK/FOXO/HIF-1 signal pathway in the treatment of rheumatoid arthritis

Bone & Joint Research, 2023
Aims: Rheumatoid arthritis (RA) is a common chronic immune disease. Berberine, as its main active ingredient, was also contained in a variety of medicinal plants such as Berberaceae, Buttercup, and Rutaceae, which are widely used in digestive system ...
Zhiqi Li, Meilin Chen, Zhaoyi Wang, Qiqi Fan, Zili Lin, Xiaoyu Tao, Jiarui Wu, Zhenquan Liu, Ruichao Lin, Chongjun Zhao   +9 more
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Macrophage Migration Inhibitory Factor Promotes Expression of Matrix Metalloproteinases 1 and 3 in Spinal Cord Astrocytes following Gecko Tail Amputation

Journal of Integrative Neuroscience, 2023
Background: The matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that play a variety of physiological and pathological roles in development, remodeling of tissues and diseases, mainly through degradation of various components of the ...
Haijun Zhang, Chunshuai Sun, Bingqiang He, Xingyuan Zhang, Huifei Hao, Yuxuan Hou, Aicheng Li, Yongjun Wang, Yingjie Wang   +8 more
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Peanut (Arachis hypogaea) Shells Extract and Apis dorsata Honey Reduce Matrix Metalloproteinase-3 in Monosodium Iodoacetate-Induced Osteoarthritic Rats

Journal of Biomedicine and Translational Research, 2020
Background: Osteoarthritis is the most common degenerative joint disease worldwide but its treatment can cause serious adverse events. Ethanol extract of peanut shells contains luteolin functioned as its main anti-inflammatory and chondroprotective agent.
Bella Stevanny, Tungki Pratama Umar, Junoretta Haviva Ernanto, Rachmat Hidayat   +3 more
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Matrix Metalloproteinase 3: A Promoting and Destabilizing Factor in the Pathogenesis of Disease and Cell Differentiation

Frontiers in Physiology, 2021
Cells must alter their expression profiles and morphological characteristics but also reshape the extracellular matrix (ECM) to fulfill their functions throughout their lifespan.
Jiangtao Wan, Guowei Zhang, Xin Li, Xianshuai Qiu, Jun Ouyang, Jingxing Dai, Shaoxiong Min   +6 more
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Involvement of the extracellular matrix proteins periostin and tenascin C in nasal polyp remodeling by regulating the expression of MMPs

Clinical and Translational Allergy, 2021
Background Tissue remodeling caused by increased MMPs is involved in the pathogenesis of chronic rhinosinusitis with nasal polyposis (CRSwNP). We previously found higher levels of periostin and tenascin C in CRSwNPs, but whether they are associated with ...
Kun Du, Min Wang, Nan Zhang, Pei Yu, Ping Wang, Ying Li, Xiangdong Wang, Luo Zhang, Claus Bachert   +8 more
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Resveratrol alleviates the interleukin-1β-induced chondrocytes injury through the NF-κB signaling pathway

Journal of Orthopaedic Surgery and Research, 2020
Background Osteoarthritis (OA) is a regular age-related disease that affects millions of people. Resveratrol (RSV) is a flavonoid with a stilbene structure with different pharmacological effects.
Hong Yi, Wei Zhang, Zhi-Ming Cui, Sheng-Yu Cui, Jian-Bo Fan, Xin-Hui Zhu, Wei Liu   +6 more
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Matrix Metalloproteinase-3 (MMP-3) Is an Endogenous Activator of the MMP-9 Secreted by Placental Leukocytes: Implication in Human Labor. [PDF]

PLoS ONE, 2015
BACKGROUND:The activity of matrix degrading enzymes plays a leading role in the rupture of the fetal membranes under normal and pathological human labor, and matrix metalloproteinase-9 (MMP-9) it is considered a biomarker of this event.
Arturo Flores-Pliego, Aurora Espejel-Nuñez, Marisol Castillo-Castrejon, Noemi Meraz-Cruz, Jorge Beltran-Montoya, Veronica Zaga-Clavellina, Sonia Nava-Salazar, Maribel Sanchez-Martinez, Felipe Vadillo-Ortega, Guadalupe Estrada-Gutierrez   +9 more
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