Collagenases and gelatinases in bone healing. The focus on mandibular fractures
Current Issues in Pharmacy and Medical Sciences, 2014 Due to high amount of collagen fibres in the structure of bone, the enzymes capable of collagen digestion play a key role in bone remodelling. Matrix metalloproteinases (MMPs), prevailing extracellular endopeptideses, can digest extracellularly located ...
Kurzepa Jacek +4 more
doaj +1 more source
Matrix Metalloproteinases and Temporomandibular Joint Disorder: A Review of the Literature [PDF]
, 2019 Temporomandibular disorders (TMD) are progressive degenerative disorders that affect the components of the temporomandibular joint (TMJ), characterized by pain and limitations in function.
Almeida, Luis Eduardo +4 more
core +1 more source
Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies
Advanced Healthcare Materials, EarlyView.Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer +10 more
wiley +1 more source
MMP Inhibitors: Experimental and Clinical Studies
The International Journal of Biological Markers, 1999 Matrix metalloproteases (MMPs) are a family of structurally related enzymes that are capable of degrading proteins of the extracellular matrix. These enzymes play a role in tissue remodelling associated with both physiological and pathogenic processes. A
D. Belotti, P. Paganoni, R. Giavazzi
doaj +1 more source
Advanced Healthcare Materials, EarlyView.This study evaluates 3D‐printed recombinant spider silk hydrogel eADF4(C16)‐RGD in a rat AV loop model for tissue engineering. Constructs with T17b endothelial progenitor cells showed enhanced vascularization and biodegradation. Results highlight the importance of scaffold design and cellular integration in improving vascular density and overall ...
Claire M. Weinhold +9 more
wiley +1 more source
Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation
Advanced Healthcare Materials, EarlyView.This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad +7 more
wiley +1 more source
Bone seeking matrix metalloproteinase-2 (MMP-2) inhibitors can prevent bone metastatic breast cancer [PDF]
, 2019 Marilena Tauro, Conor C. Lynch
openalex +1 more source
Oxygen and ROS Delivery for Infected Wound Healing and Future Prospects
Advanced Healthcare Materials, EarlyView.Bacterial infection is a major driver of delayed wound healing and postsurgical readmissions; with rising antibiotic resistance, solid peroxide–releasing biomaterials offer sustained delivery of ROS/O2 for antimicrobial control and microenvironmental modulation.
Ayden Watt +7 more
wiley +1 more source
AB1052 Comparison of several biomarkers (MMP-2, MMP-9 AND ITS INHIBITOR TIMP-1, CTX-II, CALPROTECTIN AND COMP) in the synovial fluid and serum of patients with and without septic arthritis [PDF]
, 2018 Marion Couderc +6 more
openalex +1 more source