Results 111 to 120 of about 240,787 (310)

MMP-9 inhibitor 1 and melatonin pretreatment attenuates IL-1β treatment- induced MMP-9 activity.

, 2016
MMP-9 inhibitor 1 (n = 4) and melatonin (n = 5) pretreatment attenuated IL-1β treatment-induced MMP-9 activity in RBMECs. MMP-9 activity is expressed as relative fluorescence units (RFU), plotted on the Y-axis. Data are expressed as mean ± SEM.
Himakarnika Alluri (2735689), Rickesha L. Wilson (2735674), Jason H. Huang (333420), Katie Wiggins-Dohlvik (2735671), Binu Tharakan (2735677), Chinchusha Anasooya Shaji (2735686), Yang Liu (4829), Xu Peng (365714), Savan Patel (2735683), Madhava R. Beeram (2735680), Matthew L. Davis (680366)   +10 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

Determination of Minimum Miscibility Pressure by Analytical Method [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2007
The analytical theory of one dimensional, dispersion free miscible displacement of oil by injection gas with nc component has shown that: the MMP is the lowest pressure at which any one of the initial oil, injection gas or crossover key tie lines becomes
Ali Reza Motaleby Nedjad, Mohsen Vafaie Sefti, Hassan Naderi   +2 more
doaj  

Matriksimetalloproteinaasit hengitysteiden bakteeri-infektion indikaattoreina : Trakeobronkiaalihuuhtelunesteen MMP-2-ja MMP-9-aktiivisuudet vasikan luonnollisissa pasteurella-infektioissa

, 2001
Tutkimuksessa selvitettiin vasikoiden trakeobronkiaalihuuhtelunäytteissä esiintyviä MMP-2- ja MMP-9-tasoja sekä hengitysteiden Pasteurella-infektion yhteydessä MMP-aktiivisuuksissa tapahtuvia muutoksia.
Eskelinen, Ulla
core  

The Influence of MMP-3 towards MMP-9 among Emphysematous Patients from Gingival Crevicular Fluid and Sputum [PDF]

, 2015
The elevated activity of matrix metalloproteinase (MMP)-9 has been responsible for degradation of extracellular matrix (ECM) within lung parenchyma leading to emphysema among patients suffering from chronic obstructive pulmonary disease (COPD ...
Azhary, Mulkan, Amin, Muhammad, Mulyadi, Mulyadi, Soetjipto, Soetjipto, Sunnati, Sunnati   +4 more
core  

An Improved Collagen Zymography Approach for Evaluating the Collagenases MMP-1, MMP-8, and MMP-13

BioTechniques, 2017
Collagen zymography is an SDS-PAGE-based method for detecting both the proenzyme and active forms of collagenases. Although collagen zymography is used for assessment of the matrix metalloproteinases MMP-1 and MMP-13, it can be difficult to detect these collagenases due to technical issues.
OKTAY, GÜLGÜN, Inanc, Seniz, Keles, Didem   +2 more
openaire   +4 more sources

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

Advanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu, Jiawei Wang, Wei Zhang, Zhixuan Wu, Jing Chen, Yujing He, Xiyue Duan, Yaoting He, Xin Xin, Haoyi Xiang, Yijing Wang, Chengwei Wu, Yang Yi, Qing Meng, Yuqian Qiao, Kui Cheng, Xiaojun Long, Zhangfa Song   +17 more
wiley   +1 more source

2,2’- Bipyridine Derivatives Exert Anticancer Effects by Inducing Apoptosis in Hepatocellular Carcinoma (HepG2) Cells

Journal of Hepatocellular Carcinoma
Priyanka,1,2 Somdutt Mujwar,3 Ram Bharti,1,2 Thakur Gurjeet Singh,3 Neeraj Khatri1,2 1IMTech Centre for Animal Resources & Experimentation (iCARE), CSIR-Institute of Microbial Technology (CSIR-IMTECH), Chandigarh, 160036, India; 2Academy of Scientific ...
Priyanka, Mujwar S, Bharti R, Singh TG, Khatri N   +4 more
doaj  

MMP-9 interaction with endothelial cell PAR-1.

, 2017
(A) Activation of PAR-1 by MMP-9 (pseudo color green); n = 3. (B) Expression of pERK in HUVEC cells by MMP-9 in presence and absence of anti-PAR-1; n = 3. (C). Expression of MMP-9 and PAR-1 in aortic leaflets from patients with atherosclerosis; n = 3.
Anna K. Kurdowska (3720097), Timothy C. Allen (3720088), Agnieszka Krupa (2168812), Laela M. Booshehri (3720091), Jon M. Florence (3720094)   +4 more
core   +1 more source