Results 91 to 100 of about 390,769 (349)

Genetic determinants of virulence and drug resistance of Mycobacterium avium subsp. hominissuis — a causative agent of mycobacteriosis in humans

Инфекция и иммунитет, 2020
Among the members of the large group of non-tuberculous mycobacteria (comprising more than 180 species), M. avium subsp. hominissuis (MAH) is the most significant causative agent of pulmonary infection in immunocompetent individuals as well as ...
D. A. Starkova, O. V. Narvskaya
doaj   +1 more source

MMP-9 Inhibition: a Therapeutic Strategy in Ischemic Stroke

Molecular Neurobiology, 2013
Ischemic stroke is a leading cause of disability worldwide. In cerebral ischemia there is an enhanced expression of matrix metallo-proteinase-9 (MMP-9), which has been associated with various complications including excitotoxicity, neuronal damage ...
M. Chaturvedi, L. Kaczmarek
semanticscholar   +1 more source

acdh-oeaw/mmp: filters and cones

, 2022
What's Changed docs: change field helptext for passage.places by @stefanprobst in https://github.com/acdh-oeaw/mmp/pull/182 181 missing search params for apispatialcoverage by @csae8092 in https://github.com/acdh-oeaw/mmp/pull/184 fix: omit cones ...
Daniel Stoxreiter, Peter Andorfer, stefanprobst, Marc   +3 more
core   +1 more source

Self‐Assembling Copolymers Encapsulating Single Endothelial Cells Induce Endogenous ECM Deposition and Vascular Regeneration

Advanced Materials, EarlyView.
This study presents the first demonstration of stable sub‐50‐micron single‐cell GPM vesicles fabricated through the intrinsic self‐assembly of an amphiphilic copolymer. Hierarchical assembly of cell containing GPM vesicles into microspheres enable tunable, sustained cell delivery with immune protection.
Viola B. Morris, Sangho Lee, Kalp Soni, Simon He, Matthew Huang, Dandan Chen, Dae Hoon Lee, Kyung Hee Kim, Seonggeon Cho, Laura Pencea, Divit Jain, Young‐Sup Yoon   +11 more
wiley   +1 more source

Matrix Metalloproteinase (MMP)-9: a proximal biomarker for cardiac remodeling and a distal biomarker for inflammation

Pharmacology and Therapeutics, 2013
Adverse cardiac remodeling following myocardial infarction (MI) remains a significant cause of congestive heart failure. Additional and novel strategies that improve our ability to predict, diagnose, or treat remodeling are needed.
G. Halade, Yu-Fang Jin, M. Lindsey
semanticscholar   +1 more source

MMP-2 expression and tumor aggressiveness.

, 2017
(A) Scatterplot showing that MMP-2 intensity increases with tumor grade. (B) Patients with wildtype IDH1 (wtIDH1) astrocytomas tended to have higher MMP-2 intensity compared to patients with mutated IDH1 (mIDH1) astrocytomas.
Simon K. Hermansen (3778771), Bjarne W. Kristensen (3778777), Mia D. Sørensen (3778774), Rahimsan K. Ramachandran (3778768), Charlotte Aaberg-Jessen (2889320)   +4 more
core   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Transcriptional regulation of collagenase (MMP-1, MMP-13) genes in arthritis: integration of complex signaling pathways for the recruitment of gene-specific transcription factors

Arthritis Research & Therapy, 2001
Matrix metalloproteinase (MMP)-1, MMP-8 and MMP-13 are interstitial collagenases that degrade type II collagen in cartilage; this is a committed step in the progression of rheumatoid arthritis and osteoarthritis. Of these enzymes, the expression of MMP-1
M. Vincenti, C. Brinckerhoff
semanticscholar   +1 more source

Relationship between matrix metalloproteinase-3 (MMP-3) polymorphism status and MMP release and activation

, 2011
Copyright information:Taken from "Intrinsic genetic characteristics determine tumor-modifying capacity of fibroblasts: matrix metalloproteinase-3 5A/5A genotype enhances breast cancer cell invasion"http://breast-cancer-research.com/content/9/5/R67Breast ...
Jacqueline A Shaw (40757), Deborah L Holliday (40756), Rosemary A Walker (40758), Simon Hughes (16652), J Louise Jones (40759)   +4 more
core   +1 more source

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang, Bangheng Liu, Yulei Mu, Huiqun Zhou, Liang Ma, Chenjie Xu, Dong‐An Wang   +6 more
wiley   +1 more source