Results 261 to 270 of about 396,778 (337)

A Mitochondria‐Specific Nanomedicine for Synergistic Chemo‐Photothermal Therapy and Immunogenic Activation Against Breast Cancer

Advanced Science, EarlyView.
Peptide dendrimer–based nanoplatform with mitochondria‐targeting capability was developed for synergistic chemo‐photothermal therapy. The system promotes efficient transcytosis, induces mitochondrial dysfunction, triggers immunogenic cell death (ICD), and enhance antitumor immunity by promoting dendritic cell maturation and T‐cell activation, resulting
Min Li, Jiangqi Feng, Junyang Zhuang, Qingguo Zhong, Yanda Li, Yanzhuo Lv, Shaoteng Huang, Xiangyu Huang, Mingbo Zhang, Xiaofeng Cai, Yuxin Wang, Wenping Chen, Zhenyu Duan, Zhou Chen, Kui Luo, Ning Li   +15 more
wiley   +1 more source

Depression induces ocular surface inflammation and dry eye-like changes in mice. [PDF]

Int J Ophthalmol
Lin X, Liu YW, Li JN, Ouyang WJ, Tang LY, Wu JL, Liu ZL, Wu SN, Hu JY, Liu ZG.   +9 more
europepmc   +1 more source

ПРОГНОСТИЧЕСКОЕ ЗНАЧЕНИЕ ПОЛИМОРФИЗМА ГЕНОВ MMP-9, TGF-β1 И ОБЕСПЕЧЕННОСТИ ВИТАМИНОМ D В ФОРМИРОВАНИИ ДЕРМАТО-РЕСПИРАТОРНОГО СИНДРОМА У ДЕТЕЙ

Дилбар Каттаева
openalex   +1 more source

Cockroach‐Derived Leucokinin VIII Peptide Accelerates Diabetic Skin Wound Healing by Enhancing Keratinocyte Filopodia Formation

Advanced Science, EarlyView.
This study identifies the cockroach‐derived peptide leucokinin VIII as a potent accelerator of diabetic wound healing. By activating the FAK‐ACTG1 axis, the peptide drives keratinocyte migration and filopodia formation. Delivered via a developed PLGA‐PEG‐PLGA thermosensitive hydrogel for sustained release, this approach significantly hastens wound ...
Zhengshan Qin, Jinchuan Wu, Xiehua Xiao, Xirui Wang, Nianhui Ding, Xin Zhao, Lu Ma, Jie Li, Lunkun Ma, Cehua Ou, Ning Ma, Jianguo Feng   +11 more
wiley   +1 more source

Antimicrobial, anti-inflammatory, and antioxidant effect of onion peel extract (Allium cepa L.) on periodontal pathogen Porphyromonas gingivalis: An in vitro analysis. [PDF]

Medicine (Baltimore)
Bhandari V, Mahale S, Abullais SS, Thosar S, Patil A, Alanazi S, Baba SM, Kaurani P.   +7 more
europepmc   +1 more source

Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction

Advanced Science, EarlyView.
We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang, Kai Dai, Tong Shen, Zehua Gao, Fengying Yan, Yuke Feng, Xuanlin Wang, Shaozhen Zhang, Jing Wang, Changsheng Liu   +9 more
wiley   +1 more source

Matrix metalloproteinases and risk of cardiovascular mortality and morbidity in the United Kingdom: A prospective cohort study with machine learning analysis. [PDF]

Prev Med Rep
Huang J, Jiang H, Lu Y, Ding X, Zhang C, Lin Y, Chen M.   +6 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Single-cell analyses identify independent aging processes that compete to determine cellular fate in budding yeast. [PDF]

Proc Natl Acad Sci U S A
Hotz M, Kroll-Ling RG, Thayer NH, Gottschling DE.   +3 more
europepmc   +1 more source

Effects of captopril on expression of MMP-2, 3 and TIMP-2, 3 in rat hepatic fibrosis

, 2003
Qian Li, Guiying Zhang, Xinhua Li, Meihua Xu   +3 more
openalex   +1 more source