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Expression of MMP-10, MMP-21, MMP-26, and MMP-28 in Merkel cell carcinoma

Virchows Archiv, 2009
Merkel cell carcinoma (MCC) is an aggressive cutaneous tumor with poor outcome and increasing incidence. We examined by immunohistochemistry the expression of three novel matrix metalloproteinases (MMPs)-MMP-21, MMP-26, and MMP-28-in 44 primary MCC tumors and six lymph node metastases while MMP-10 served as a positive control. Their mRNA expression was
Sari, Suomela   +5 more
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Matrix Metalloproteinase (MMP)-7 Activates MMP-8 But Not MMP-13

Medicinal Chemistry, 2006
Matrix Metalloproteinases (MMPs) are a class of zinc-dependent enzymes that degrade extracellular matrix components, particularly collagen. MMPs have been implicated in a diverse list of pathological processes, including cancer and cardiovascular disease.
S, Dozier, G P, Escobar, M L, Lindsey
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