Results 231 to 240 of about 390,769 (349)

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

Advanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou, Lei Zhang, Xingyu Cai, Jiajia Su, Guangyu Dai, Xue Chen, Hanming Wang, Jia Hua, Jianping Liu, Chunmeng Sun, Xiancheng Chen, Erhao Wang, Wenli Zhang   +12 more
wiley   +1 more source

Formal Comment on "Platelet-leucocyte interactions drive MMP-mediated tissue damage in tuberculosis" (Kirwan et al., 2026). [PDF]

PLoS Pathog
Shan Q.
europepmc   +1 more source

Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy

Advanced Science, EarlyView.
A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao, Yuechen Han, Jie Li, Peng Luo, Lin Qi, Zhiwei Xia, Xiaosong Li, Quan Cheng, Chenshen Huang, Wantao Wu, Hao Zhang   +10 more
wiley   +1 more source

Correlation between MMP-3-1171 5A/6A polymorphism and the risk of Alzheimer's disease: A meta-analysis. [PDF]

Medicine (Baltimore)
Wang Y, Zhu S, Ma Y, Chen X, Zhou M.
europepmc   +1 more source

Human neutrophils uniquely release TIMP-free MMP-9 to provide a potent catalytic stimulator of angiogenesis

Proceedings of the National Academy of Sciences of the United States of America, 2007
V. Ardi, T. Kupriyanova, E. Deryugina, J. Quigley   +3 more
semanticscholar   +1 more source

Pathological Signal‐Responsive Nanoplatforms for Sepsis: Integrating Biomarker Sensing With Spatiotemporal Drug Delivery and Immunomodulation

Advanced Science, EarlyView.
Biomarker‐triggered nanoplatforms transform sepsis therapy by coupling pathological sensing with precision drug release. This review reveals how microenvironment‐responsive nanomedicines enable stage‐specific intervention, improve therapeutic efficacy, and minimize systemic toxicity, while highlighting emerging opportunities for AI‐assisted and ...
Yukun Liu, Kang Wang, Kwet Kyawl Yan, Zhikai Xu, Xuan Zhao, Xiangjun Bai, Zhanfei Li, Yuchang Wang   +7 more
wiley   +1 more source

Salivary Lactate Dehydrogenase and Matrix Metalloproteinase-8 as Predictive Biomarkers in Early Childhood Caries: A Cross-sectional Study. [PDF]

Int J Clin Pediatr Dent
Kommalapati V, Soorneedi N, Supraja AN, Ravula NR, Harika R, Manojna NL.   +5 more
europepmc   +1 more source

The Membrane-Anchored MMP Inhibitor RECK Is a Key Regulator of Extracellular Matrix Integrity and Angiogenesis

Cell, 2001
Jun Oh, Rei Takahashi, S. Kondo, A. Mizoguchi, Eijiro Adachi, R. M. Sasahara, Sachiko Nishimura, Yukio Imamura, H. Kitayama, David B. Alexander, Chizuka Ide, T. Horan, T. Arakawa, Hisahito Yoshida, Shinsuke Nishikawa, Y. Itoh, Motoharu Seiki, S. Itohara, Chiaki Takahashi, M. Noda   +19 more
semanticscholar   +1 more source

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

Advanced Science, EarlyView.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou, Xing Liu, Cuiyi Wang, Xiaoxuan Zhao, Pengrun Zhang, Jingjing Gu, Qiuhua Sun, Malcolm Xing, Yeqin Yang   +8 more
wiley   +1 more source

Combined Effect of Silybin and Sodium Acetylated Hyaluronate on UV-Induced Photoaging. [PDF]

Skin Res Technol
Hou S, Song H, Zhang J, Li A.
europepmc   +1 more source