Results 111 to 120 of about 399 (121)

FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice. [PDF]

open access: yesCell
Momenilandi M   +72 more
europepmc   +1 more source

MmuPV1 infection and tumor development of T cell-deficient mice is prevented by passively transferred hyperimmune sera from normal congenic mice immunized with MmuPV1 virus-like particles (VLPs)

open access: yesExperimental and Molecular Pathology, 2016
Infection by mouse papillomavirus (PV), MmuPV1, of T cell-deficient, B6.Cg-Foxn1(nu)/J nude mice revealed that four, distinct squamous papilloma phenotypes developed simultaneously after infection of experimental mice. Papillomas appeared on the muzzle, vagina, and tail at or about day 42days post-inoculation.
Shin-Je Ghim   +2 more
exaly   +5 more sources

Mouse papillomavirus MmuPV1 infects oral mucosa and preferentially targets the base of the tongue

open access: yesVirology, 2016
In 2010, a new mouse papillomavirus, MmuPV1, was discovered in a colony of NMRI- Foxn1(nu)/Foxn1(nu) athymic mice in India. This finding was significant because it was the first papillomavirus to be found in a laboratory mouse. In this paper we report successful infections of both dorsal and ventral surfaces of the rostral tongues of outbred athymic ...
Nancy M Cladel   +2 more
exaly   +4 more sources

The human papillomavirus 16 E5 gene potentiates MmuPV1-Dependent pathogenesis

open access: yesVirology, 2020
The papillomavirus E5 gene contributes to transformation and tumorigenesis; however, its exact function in these processes and viral pathogenesis is unclear. While E5 is present in high-risk mucosotropic HPVs that cause anogenital and head and neck cancers, it is absent in cutaneous HPVs and the recently discovered mouse papillomavirus (MmuPV1), which ...
Megan E Spurgeon   +2 more
exaly   +3 more sources

Development of an in vivo infection model to study Mouse papillomavirus-1 (MmuPV1) [PDF]

open access: yesJournal of Virological Methods, 2018
Preclinical model systems to study multiple features of the papillomavirus life cycle are extremely valuable tools to aid our understanding of Human Papillomavirus (HPV) biology, disease progression and treatments. Mouse papillomavirus (MmuPV1) is the first ever rodent papillomavirus that can infect the laboratory strain of mice and was discovered ...
Aayushi Uberoi, Paul F Lambert
exaly   +3 more sources

T cell-mediated antitumor immune response eliminates skin tumors induced by mouse papillomavirus, MmuPV1

open access: yesExperimental and Molecular Pathology, 2017
Previous studies of naturally occurring mouse papillomavirus (PV) MmuPV1-induced tumors in B6.Cg-Foxn1nu/nu mice suggest that T cell deficiency is necessary and sufficient for the development of such tumors. To confirm this, MmuPV1-induced tumors were transplanted from T cell-deficient mice into immunocompetent congenic mice.
Paula M Chilton   +2 more
exaly   +3 more sources
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