Results 181 to 190 of about 8,440 (225)

mNGS in clinical microbiology laboratories: on the road to maturity [PDF]

open access: yesCritical Reviews in Microbiology, 2019
Metagenomic next-generation sequencing (mNGS) is increasingly being applied in clinical laboratories for unbiased culture-independent diagnosis. Whether it can be a next routine pathogen identification tool has become a topic of concern. We review the current implementation of this new technology for infectious disease diagnostics and discuss the ...
Jinming Li, Dongsheng Han, Ping Tan
exaly   +4 more sources

The Clinical Impact of Metagenomic Next-Generation Sequencing (mNGS) Test in Hospitalized Patients with Suspected Sepsis: A Multicenter Prospective Study [PDF]

open access: yesDiagnostics, 2023
Background: Metagenomic Next Generation Sequencing (mNGS) has the potential to detect pathogens rapidly. We aimed to assess the diagnostic performance of mNGS in hospitalized patients with suspected sepsis and evaluate its role in guiding antimicrobial ...
Hua Zhou, Yu-Ping Li, Shu-Yun Xu
exaly   +2 more sources

mNGS for identifying pathogens in febrile neutropenic children with hematological diseases [PDF]

open access: yesInternational Journal of Infectious Diseases, 2022
To investigate the application value of metagenomic next-generation sequencing (mNGS) in children with hematological diseases presenting with Febrile Neutropenia (FN).We retrospectively analyzed the clinical data of 49 hematological children with FN, and compared the results of mNGS with those of traditional pathogen detection (TPD) and the prognoses ...
Fang Guo
exaly   +4 more sources

mNGS for the diagnosis of infection in patients with CTDs.

2022
Metagenomic next-generation sequencing (mNGS) is emerging as a promising technique for pathogens detection. Most patients with CTDs under immunosuppression are susceptible to infection. However, reports on the application of mNGS in patients with connective tissue diseases (CTDs) who were suspected infection remain scarce.
openaire   +1 more source

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