Results 11 to 20 of about 9,323 (234)

Comparison of quality/quantity mNGS and usual mNGS for pathogen detection in suspected pulmonary infections [PDF]

Frontiers in Cellular and Infection Microbiology, 2023
Improved metagenomic next-generation sequencing (mNGS), for example, quality/quantity mNGS (QmNGS), is being used in the diagnosis of pulmonary pathogens. There are differences between QmNGS and the usual mNGS (UmNGS), but reports that compare their detection performances are rare.
Zhan Zhao, Xuefen Chen, Xuefen Chen, Yubao Wang, Jing Feng   +4 more
openaire   +4 more sources

Diagnostic Role of mNGS in Polymicrobial Periprosthetic Joint Infection

Journal of Clinical Medicine, 2023
Objectives: The purpose of this study was to explore the clinical value of metagenomic next-generation sequencing (mNGS) in the diagnosis of polymicrobial periprosthetic joint infection (PJI). Methods: Patients with complete data who underwent surgery at our hospital between July 2017 and January 2021 for suspected periprosthetic joint infection (PJI),
Jian Mei, Hongxin Hu, Si Zhu, Haiqi Ding, Zida Huang, Wenbo Li, Bin Yang, Wenming Zhang, Xinyu Fang   +8 more
openaire   +3 more sources

Spinal infections? mNGS combined with microculture and pathology for answers [PDF]

Infection and Drug Resistance
Abstract Background This study focuses on the efficacy of genome sequencing technology (mNGS) in diagnosing infections of the spine and the development of therapeutic regimens combining mNGS, microbiological cultures, and pathological investigations to provide new perspectives for the treatment of spinal infections.
Jiayi Chen, Yonghong Liu, Shengsheng Huang, Zixiang Pang, Qian Wei, Yuzhen Liu, Hongyuan Qin, Yuanming Chen   +7 more
openaire   +5 more sources

The Impact of mNGS Technology in the Etiological Diagnosis of Severe Pneumonia in Children During the Epidemic of COVID-19

Infection and Drug Resistance, 2023
Changjiang Yu,1,* Wei Guo,1,2,* Zhulai Zhang,1,* Yuting Ma,3,* Xiaobei Cao,1 Na Sun,1 Yingyao Cui,1 Yunshen Wang,1 Wenyu Cui,1 Yongsheng Xu,1 Jianghua Zhan2,4 1Department of Pediatric Respiratory Medicine, Tianjin Children’s Hospital ...
Yu C, Guo W, Zhang Z, Ma Y, Cao X, Sun N, Cui Y, Wang Y, Cui W, Xu Y, Zhan J   +10 more
doaj   +1 more source

Comparison of the Impact of tNGS with mNGS on Antimicrobial Management in Patients with LRTIs: A Multicenter Retrospective Cohort Study [PDF]

Infection and Drug Resistance
Dan Li,1– 3,* Qingling Li,4,* Zhen Huang,2 Wenhao Wu,2 Xinyuan Fan,2 Jing Liu,2 Ruoran Li,2 Qi Zhang,2 Xin Su1 1Department of Respiratory and Critical Care Medicine, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University ...
Li D, Li Q, Huang Z, Wu W, Fan X, Liu J, Li R, Zhang Q, Su X   +8 more
doaj   +1 more source

Validation of mNGS results using extensive lab and clinical data

BMC Microbiology
Interpreting the results of metagenomic next-generation sequencing (mNGS) presents a significant challenge in both clinical and laboratory contexts.A retrospective analysis was conducted to validate mNGS findings, with a particular emphasis on Mycobacterium tuberculosis, Mycoplasma pneumoniae, and Pneumocystis jirovecii as representative pathogens ...
Zhen Zhang, Lei Tian
openaire   +4 more sources

MNG-2 Meningioma with aseptic meningitis [PDF]

Neuro-Oncology Advances, 2021
Abstract The patient, a woman in her seventies, visited the Department of Neurology at our hospital one month ago with transient right hemiparesis, and was referred to our department because a CT scan showed a 4cm extramedullary lesion in the left convexity.
Hideki Nakajima, Takuro Tsuchiya, Shigetoshi Shimizu   +2 more
openaire   +1 more source

A Review of the Application of mNGS in Hematologic Malignancy

Intensive Care Research, 2023
AbstractInfection remains a major cause of mortality in individuals diagnosed with hematologic malignancies, both in children and adults. Although the range of infections affecting these patients has undergone significant changes with the widespread use of antibiotics, it is accompanied by an increasing number of drug-resistant strains.
Luyao Shi, Tingting Lei, Yankun Huo, Yufei Chen, Chong Wang, Shujuan Wang   +5 more
openaire   +2 more sources

Diagnosis of complication in lung transplantation by TBLB + ROSE + mNGS [PDF]

Open Medicine, 2020
Abstract Lung transplantation is a potentially life-saving therapy for patients with terminal respiratory illnesses. Long-term survival is limited by the development of a variety of opportunistic infections and rejection. Optimal means of differential diagnosis of infection and rejection have not been established.
Wang Qing, Feng Jing, Zhang Ji, Shi Lingzhi, Jin Zhixian, Liu Dong, Wu Bo, Chen Jingyu   +7 more
openaire   +3 more sources

Prognosis of Patients Infected With <i>Talaromyces marneffei</i> Across Various Risk Factors. [PDF]

J Gen Fam Med
ABSTRACT Background Talaromyces marneffei (TM) is an opportunistic infectious fungus, and more patients in HIV‐negative populations are infected with TM. Methods We reviewed the adult patients with TM infections (TMIs) between November 1, 2020 and April 30, 2025.
Wang J, Wang Y, Wang R.
europepmc   +2 more sources