Comparison of quality/quantity mNGS and usual mNGS for pathogen detection in suspected pulmonary infections [PDF]
Improved metagenomic next-generation sequencing (mNGS), for example, quality/quantity mNGS (QmNGS), is being used in the diagnosis of pulmonary pathogens. There are differences between QmNGS and the usual mNGS (UmNGS), but reports that compare their detection performances are rare.
Zhan Zhao +4 more
openaire +5 more sources
Diagnostic Role of mNGS in Polymicrobial Periprosthetic Joint Infection [PDF]
Objectives: The purpose of this study was to explore the clinical value of metagenomic next-generation sequencing (mNGS) in the diagnosis of polymicrobial periprosthetic joint infection (PJI). Methods: Patients with complete data who underwent surgery at our hospital between July 2017 and January 2021 for suspected periprosthetic joint infection (PJI),
Jian Mei +8 more
openaire +3 more sources
Spinal infections? mNGS combined with microculture and pathology for answers [PDF]
Abstract Background This study focuses on the efficacy of genome sequencing technology (mNGS) in diagnosing infections of the spine and the development of therapeutic regimens combining mNGS, microbiological cultures, and pathological investigations to provide new perspectives for the treatment of spinal infections.
Jiayi Chen +7 more
openaire +6 more sources
The diagnostic value of RNA-mNGS and DNA-mNGS in differentiating bacterial infection from colonization in the lower respiratory tract [PDF]
BackgroundMetagenomic next-generation sequencing(mNGS) has been widely used in the pathogenetic diagnosis of lower respiratory tract infections. However, the interpretation of pathogens detected by mNGS remains inconclusive.ObjectiveOur study aimed to compare the differential diagnostic value of sequencing reads and the relative abundance of bacteria ...
Duan, Yuanfang +4 more
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Validation of mNGS results using extensive lab and clinical data [PDF]
Interpreting the results of metagenomic next-generation sequencing (mNGS) presents a significant challenge in both clinical and laboratory contexts.A retrospective analysis was conducted to validate mNGS findings, with a particular emphasis on Mycobacterium tuberculosis, Mycoplasma pneumoniae, and Pneumocystis jirovecii as representative pathogens ...
Zhen Zhang, Lei Tian
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The Impact of mNGS Technology in the Etiological Diagnosis of Severe Pneumonia in Children During the Epidemic of COVID-19 [PDF]
Changjiang Yu,1,* Wei Guo,1,2,* Zhulai Zhang,1,* Yuting Ma,3,* Xiaobei Cao,1 Na Sun,1 Yingyao Cui,1 Yunshen Wang,1 Wenyu Cui,1 Yongsheng Xu,1 Jianghua Zhan2,4 1Department of Pediatric Respiratory Medicine, Tianjin Children’s Hospital ...
Yu C +10 more
doaj +1 more source
Comparison of the Impact of tNGS with mNGS on Antimicrobial Management in Patients with LRTIs: A Multicenter Retrospective Cohort Study [PDF]
Dan Li,1– 3,* Qingling Li,4,* Zhen Huang,2 Wenhao Wu,2 Xinyuan Fan,2 Jing Liu,2 Ruoran Li,2 Qi Zhang,2 Xin Su1 1Department of Respiratory and Critical Care Medicine, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University ...
Li D +8 more
doaj +2 more sources
MNG-2 Meningioma with aseptic meningitis [PDF]
Abstract The patient, a woman in her seventies, visited the Department of Neurology at our hospital one month ago with transient right hemiparesis, and was referred to our department because a CT scan showed a 4cm extramedullary lesion in the left convexity.
Hideki Nakajima +2 more
openaire +1 more source
We retrospectively enrolled 108 patients with infectious disease and noninfectious disease who visited West China Hospital of Sichuan University from January 2019 to June 2022.
Linhui Yang (17293264)
core +1 more source

