Results 11 to 20 of about 9,951 (244)

Comparison of quality/quantity mNGS and usual mNGS for pathogen detection in suspected pulmonary infections [PDF]

Frontiers in Cellular and Infection Microbiology, 2023
Improved metagenomic next-generation sequencing (mNGS), for example, quality/quantity mNGS (QmNGS), is being used in the diagnosis of pulmonary pathogens. There are differences between QmNGS and the usual mNGS (UmNGS), but reports that compare their detection performances are rare.
Zhan Zhao, Xuefen Chen, Xuefen Chen, Yubao Wang, Jing Feng   +4 more
openaire   +4 more sources

mNGS facilitates the accurate diagnosis and antibiotic treatment of suspicious critical CNS infection in real practice: A retrospective study

Open Life Sciences, 2023
Whether metagenomic next-generation sequencing (mNGS) could benefit patients with suspected severe central nervous system (CNS) infection in terms of diagnosis and antibiotic treatment remains unknown.
Miao Su, Cunzhou Shen
exaly   +2 more sources

Diagnostic Role of mNGS in Polymicrobial Periprosthetic Joint Infection

Journal of Clinical Medicine, 2023
Objectives: The purpose of this study was to explore the clinical value of metagenomic next-generation sequencing (mNGS) in the diagnosis of polymicrobial periprosthetic joint infection (PJI). Methods: Patients with complete data who underwent surgery at our hospital between July 2017 and January 2021 for suspected periprosthetic joint infection (PJI),
Jian Mei, Hongxin Hu, Si Zhu, Haiqi Ding, Zida Huang, Wenbo Li, Bin Yang, Wenming Zhang, Xinyu Fang   +8 more
openaire   +3 more sources

Evaluation of the Diagnostic Performance of mNGS in Detecting Intra-Abdominal Infections of the Emergency Department Patients

Infection and Drug Resistance, 2023
Liang Zheng,1,* Zhoujun Kang,1,* Ru Wang,2 Meng Lv,2 Zhirui Gao,1 Haizhou Xu,1 Meitang Wang1 1Emergency Department, Changhai Hospital Affiliated to Navy Medical University, Shanghai, People’s Republic of China; 2Genoxor Medical Science and ...
Zheng L, Kang Z, Wang R, Lv M, Gao Z, Xu H, Wang M   +6 more
doaj   +1 more source

Spinal infections? mNGS combined with microculture and pathology for answers [PDF]

Infection and Drug Resistance
Abstract Background This study focuses on the efficacy of genome sequencing technology (mNGS) in diagnosing infections of the spine and the development of therapeutic regimens combining mNGS, microbiological cultures, and pathological investigations to provide new perspectives for the treatment of spinal infections.
Jiayi Chen, Yonghong Liu, Shengsheng Huang, Zixiang Pang, Qian Wei, Yuzhen Liu, Hongyuan Qin, Yuanming Chen   +7 more
openaire   +5 more sources

The Impact of mNGS Technology in the Etiological Diagnosis of Severe Pneumonia in Children During the Epidemic of COVID-19

Infection and Drug Resistance, 2023
Changjiang Yu,1,* Wei Guo,1,2,* Zhulai Zhang,1,* Yuting Ma,3,* Xiaobei Cao,1 Na Sun,1 Yingyao Cui,1 Yunshen Wang,1 Wenyu Cui,1 Yongsheng Xu,1 Jianghua Zhan2,4 1Department of Pediatric Respiratory Medicine, Tianjin Children’s Hospital ...
Yu C, Guo W, Zhang Z, Ma Y, Cao X, Sun N, Cui Y, Wang Y, Cui W, Xu Y, Zhan J   +10 more
doaj   +1 more source

Comparison of the Impact of tNGS with mNGS on Antimicrobial Management in Patients with LRTIs: A Multicenter Retrospective Cohort Study [PDF]

Infection and Drug Resistance
Dan Li,1– 3,* Qingling Li,4,* Zhen Huang,2 Wenhao Wu,2 Xinyuan Fan,2 Jing Liu,2 Ruoran Li,2 Qi Zhang,2 Xin Su1 1Department of Respiratory and Critical Care Medicine, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University ...
Li D, Li Q, Huang Z, Wu W, Fan X, Liu J, Li R, Zhang Q, Su X   +8 more
doaj   +1 more source

A Case Report of Cutaneous Anthrax Diagnosed by Using a Metagenomic Next-Generation Sequencing (mNGS) Approach

Infection and Drug Resistance, 2023
Yushan Liu,1,2 Gezhi Zheng,1,3 Jing Li,1,3 Nan Yang,1– 4 Juan Li,1,2 Zhengwen Liu,1– 4 Qunying Han,1– 4 Yingren Zhao,1– 4 Fenjing Du,1,3 Yingli He,1,* Taotao Yan1,* 1Department of Infectious Diseases, The First Affiliated Hospital of Xi’an ...
Qunying Han, Taotao Yan, Yushan Liu
exaly   +2 more sources

Validation of mNGS results using extensive lab and clinical data

BMC Microbiology
Interpreting the results of metagenomic next-generation sequencing (mNGS) presents a significant challenge in both clinical and laboratory contexts.A retrospective analysis was conducted to validate mNGS findings, with a particular emphasis on Mycobacterium tuberculosis, Mycoplasma pneumoniae, and Pneumocystis jirovecii as representative pathogens ...
Zhen Zhang, Lei Tian
openaire   +4 more sources

MNG-2 Meningioma with aseptic meningitis [PDF]

Neuro-Oncology Advances, 2021
Abstract The patient, a woman in her seventies, visited the Department of Neurology at our hospital one month ago with transient right hemiparesis, and was referred to our department because a CT scan showed a 4cm extramedullary lesion in the left convexity.
Hideki Nakajima, Takuro Tsuchiya, Shigetoshi Shimizu   +2 more
openaire   +1 more source