Results 51 to 60 of about 9,951 (244)

Grtp1 Safeguards Against Paternal Reproductive Aging and Intergenerational Behavioral Deficits by Preserving Redox Homeostasis

Advanced Science, EarlyView.
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu, Shanyao Liu, Haixin Liang, Jiani Yang, Yanhe Li, Jiqing Yin, Xueguang Zhang, Yan Zhang, Dandan Bai, Zihui Yan, Zhuoao Zhang, Yanping Jia, Kuisheng Liu, Yifan Sheng, Jiani Xiang, Chenxiang Xi, Baoxing Dong, Xinyi Lei, Jiayu Chen, Hong Wang, Yi Guo, Yanping Zhang, Shaorong Gao, Wenqiang Liu   +23 more
wiley   +1 more source

Table_2_Comparison of quality/quantity mNGS and usual mNGS for pathogen detection in suspected pulmonary infections.xlsx

, 2023
Improved metagenomic next-generation sequencing (mNGS), for example, quality/quantity mNGS (QmNGS), is being used in the diagnosis of pulmonary pathogens.
Jing Feng (177843), Xuefen Chen (16713084), Zhan Zhao (3190152), Xuefen Chen, Jing Feng, Zhan Zhao, Yubao Wang, Yubao Wang (6524833)   +7 more
core   +1 more source

Value of mNGS in sonication fluid for the diagnosis of periprosthetic joint infection [PDF]

Arthroplasty, 2019
AbstractObjectiveTo evaluate the effectiveness of metagenomics next-generation sequencing (mNGS) for the detection of pathogenic microorganisms in periprosthetic joint infection (PJI) using the sonication fluid from removed prosthesis.MethodsIn this prospective diagnostic cohort study, 44 patients who underwent revision arthroplasty in our hospital ...
Chongjing Zhang, Xinyu Fang, Zida Huang, Wenbo Li, Chao-fan Zhang, Bin Yang, Wenming Zhang   +6 more
openaire   +3 more sources

In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans

Cytoskeleton, EarlyView.
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley   +1 more source

Clinical Efficacy and Diagnostic Value of Metagenomic Next-Generation Sequencing for Pathogen Detection in Patients with Suspected Infectious Diseases: A Retrospective Study from a Large Tertiary Hospital

Infection and Drug Resistance, 2023
Yang-Hua Xiao,1,2 Mei-Fang Liu,1 Hongwen Wu,1,3 De-Rong Xu,1 Rui Zhao1 1Department of Clinical Laboratory, Medical Center for Burn and Plastic Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, People’s Republic of China; 2School of
Xiao YH, Liu MF, Wu H, Xu DR, Zhao R
doaj  

MNG-2 AN ANAPLASTIC MENINGIOMA WITH THE DIFFERENTIATION INTO OSTEOSARCOMA TISSUE

Neuro-Oncology Advances, 2022
Abstract Eighty-two year old woman developed motor aphasia. A brain MRI revealed an (1) extramedullary tumor adhering to the dura mater which enhanced almost uniformly and (2) an intramedullary tumor in the left frontal lobe. She underwent surgery in which we removed both tumors.
Junichi Adachi, Hiroyuki Komine, Atsushi Sasaki   +2 more
openaire   +1 more source

Engineering and Characterization of a Fluorescent Fission Yeast Arp2/3 Complex for Single Molecule Mechanistic Investigations

Cytoskeleton, EarlyView.
ABSTRACT Arp2/3 complex is a seven‐component protein complex that facilitates the assembly of branched actin filament networks by binding to pre‐existing “mother” actin filaments and initiating the nucleation of new branched “daughter” filaments. Arp2/3 complex must be activated by a nucleation promoting factor such as the WASP/Scar protein family. The
Caitlin A. Anderson, Meghan E. O'Connell, Kaitlin E. Homa, Cristian Suarez, Michael L. James, Kashmeera D. Baboolall, Vilmos Zsolnay, Vladimir Sirotkin, David R. Kovar   +8 more
wiley   +1 more source

qPCR positive samples with respective mNGS results.

, 2019
qPCR positive samples with respective mNGS results.
Marianne Aanerud (318457), Aloys C. M. Kroes (7542383), Ellen C. Carbo (7542371), Igor Sidorov (7329359), Tomas M. Eagan (7392587), Pieter S. Hiemstra (7392584), Anneloes L. van Rijn (7542368), Nikos Pappas (7542374), Mariet Feltkamp (7542377), Eric C. J. Claas (7542380), Sander van Boheemen (187826), Hailiang Mei (3404261), Per Bakke (164964), Jutte J. C. de Vries (7542386)   +13 more
core   +1 more source

Brain Abscess Caused by Nocardia brevicatena in an Immunocompetent Patient: A Case Report

Infection and Drug Resistance, 2022
Xiaoxu Li,1,* Shifang Zhuang,2,* Lin He,2 Shanmei Wang,3 Ming Zhao,1 Xiaodong Lyu4 1Department of Neurosurgery, the Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, People’s Republic of China; 2Genskey Medical
Li X, Zhuang S, He L, Wang S, Zhao M, Lyu X   +5 more
doaj  

Clinical application of amplification-based versus amplification-free metagenomic next-generation sequencing test in infectious diseases

Frontiers in Cellular and Infection Microbiology, 2023
BackgroundRecently, metagenomic next-generation sequencing (mNGS) has been used in the diagnosis of infectious diseases (IDs) as an emerging and powerful tool.
Zhe-Ying Wang, Zhe-Ying Wang, Lu-Lu Li, Xue-Lei Cao, Xue-Lei Cao, Ping Li, Ping Li, Jian Du, Ming-Jin Zou, Li-Li Wang, Li-Li Wang   +10 more
doaj   +1 more source