Results 51 to 60 of about 9,323 (234)

In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans

Cytoskeleton, EarlyView.
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley   +1 more source

A Paired Comparison of Plasma and Bronchoalveolar Lavage Fluid for Metagenomic Next-Generation Sequencing in Critically Ill Patients with Suspected Severe Pneumonia

Infection and Drug Resistance, 2022
Ting Sun,1 Yijie Liu,2 Ying Cai,3 Tianshu Zhai,3 Yun Zhou,4 Bin Yang,5 Xiaojing Wu,3,* Qingyuan Zhan1,3,* 1Capital Medical University China-Japan Friendship School of Clinical Medicine, Beijing, People’s Republic of China; 2Graduate School of ...
Sun T, Liu Y, Cai Y, Zhai T, Zhou Y, Yang B, Wu X, Zhan Q   +7 more
doaj  

Exploring the pathogen diagnosis and prognostic factors of severe COVID-19 using metagenomic next-generation sequencing: A retrospective study [PDF]

Journal of Medical Biochemistry
Background: This study aimed to identify pathogens and factors that predict the outcome of severe COVID-19 by utilizing metagenomic next-generation sequencing (mNGS) technology.
Zeng Weizhong, Liang Yanchao, He Xiaoyuan, Chen Fangwei, Xiong Jiali, Wen Zhenhua, Tang Liang, Chen Xun, Zhang Juan   +8 more
doaj   +1 more source

Clinical features of varicella-zoster virus caused neurological diseases detected by metagenomic next-generation sequencing

Open Medicine, 2023
Clinical presentation of central nervous system (CNS) infections caused by varicella-zoster virus (VZV) is highly sophisticated, making identification challenging.
Xie Shuhua, Yang Xuying, Xia Han, Lai Jinxing, Liu Qing, Lu Zhijuan, He Dehai, Liu Xianghong   +7 more
doaj   +1 more source

Comparison of metagenomic next-generation sequencing using cell-free DNA and whole-cell DNA for the diagnoses of pulmonary infections

Frontiers in Cellular and Infection Microbiology, 2022
Although the fast-growing metagenomic next-generation sequencing (mNGS) has been used in diagnosing infectious diseases, low detection rate of mNGS in detecting pathogens with low loads limits its extensive application.
Ping He, Jing Wang, Rui Ke, Wei Zhang, Pu Ning, Dexin Zhang, Xia Yang, Hongyang Shi, Ping Fang, Zongjuan Ming, Wei Li, Jie Zhang, Xilin Dong, Yun Liu, Jiemin Zhou, Han Xia, Shuanying Yang   +16 more
doaj   +1 more source

Table_3_Enhancing urinary tract infection diagnosis for negative culture patients with metagenomic next-generation sequencing (mNGS).xlsx

, 2023
BackgroundMetagenomic next-generation sequencing (mNGS) is a promising technology that allows unbiased pathogen detection and is increasingly being used for clinical diagnoses.
Zhouliang Wu (13930074), Han Xia (444366), Chong Shen (173768), Zhe Zhang (81603), Huifen Yang (10699011), Hongjun Li (126335), Lei Wang (6656), Kaipeng Jia (14712079), Mingze Tang (14712082), Shiwang Huang (13930086), Hailong Hu (581221), Yuda Lin (11361612), Gangjian Zhao (13930083)   +12 more
core   +1 more source

Engineering and Characterization of a Fluorescent Fission Yeast Arp2/3 Complex for Single Molecule Mechanistic Investigations

Cytoskeleton, EarlyView.
ABSTRACT Arp2/3 complex is a seven‐component protein complex that facilitates the assembly of branched actin filament networks by binding to pre‐existing “mother” actin filaments and initiating the nucleation of new branched “daughter” filaments. Arp2/3 complex must be activated by a nucleation promoting factor such as the WASP/Scar protein family. The
Caitlin A. Anderson, Meghan E. O'Connell, Kaitlin E. Homa, Cristian Suarez, Michael L. James, Kashmeera D. Baboolall, Vilmos Zsolnay, Vladimir Sirotkin, David R. Kovar   +8 more
wiley   +1 more source

Clinical pathogen profiles and lung microbiome features in lung infection patients and concurrent cancer: insights from metagenomics next-generation sequencing

Open Life Sciences
Pulmonary infections in immunocompromised cancer patients present significant diagnostic and therapeutic challenges. From Dec 2021 to Aug 2023, 85 patients with pulmonary infection were enrolled and categorized into a cancer group (CP, n = 20) and a non ...
Liu Dandan, Ma Yuehong, Ma Qian, Huang Huihua, Li Tianyu, Wang Jin, Zhang Jin, Cheng Xuesong, Ge Xueru, Chen Yan, Zhang Yanbei   +10 more
doaj   +1 more source

The Performance of Metagenomic Next-Generation Sequence in the Diagnosis of Suspected Opportunistic Infections in Patients with Acquired Immunodeficiency Syndrome [Corrigendum]

Infection and Drug Resistance, 2023
Liu L, Yuan M, Sun S, et al. Infect Drug Resist. 2022;15:5645–5653. The authors have advised that affiliation 1 on page 5645 is incorrect.
Liu L, Yuan M, Sun S, Wang J, Shi Y, Yu Y, Su X   +6 more
doaj  

MNGs in the lung of patients with GPA express TRAP.

, 2013
Alveolar macrophages in control (A) and unaffected tissue in GPA lung (B) expressed TRAP (bright purple), and MNGs were not noted in normal lung tissue. A population of MNGs within the GPA granulomata expressed TRAP.
Frederic Askin (312176), Jon T. Giles (312177), Antony Rosen (192809), Stuart M. Levine (312179), Jin Kyun Park (312175), Marc K. Halushka (312178)   +5 more
core   +1 more source