Results 131 to 140 of about 410,012 (337)
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Mobile transporter path planning [PDF]
The use of a genetic algorithm (GA) for solving the mobile transporter path planning problem is investigated. The mobile transporter is a traveling robotic vehicle proposed for the space station which must be able to reach any point of the structure ...
Baffes, Paul, Wang, Lui
core +1 more source
Information-Matter Bipolarity of the Human Organism and Its Fundamental Circuits: From Philosophy to Physics/Neurosciences-Based Modeling [PDF]
, 2020 Starting from a philosophical perspective, which states that the living structures are actually a combination between matter and information, this article presents the results on an analysis of the bipolar information-matter structure of the ...
Gaiseanu, Florin
core
A Wideband Direct Data Domain Genetic Algorithm Beamforming [PDF]
, 2015 In this paper, a wideband direct data-domain genetic algorithm beamforming is presented. Received wideband signals are decomposed to a set of narrow sub-bands using fast Fourier transform.
Elkamchouchi, H. M., Hassan, M. M.
core +2 more sources
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Evolving Gene Regulatory Networks with Mobile DNA Mechanisms
, 2013 This paper uses a recently presented abstract, tuneable Boolean regulatory network model extended to consider aspects of mobile DNA, such as transposons.
Adamatzky, Andrew, Bull, Larry
core +1 more source
Mobile Antibiotic Resistance Encoding Elements Promote Their Own Diversity [PDF]
, 2011 Integrating conjugative elements (ICEs) are a class of bacterial mobile genetic elements that disseminate via conjugation and then integrate into the host cell genome. The SXT/R391 family of ICEs consists of more than 30 different elements that all share
Burrus, Vincent +3 more
core +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Regulation of solvent tolerance in Pseudomonas putida S12 mediated by mobile elements
Microbial Biotechnology, 2017 Summary Organic solvent‐tolerant bacteria are outstanding and versatile hosts for the bio‐based production of a broad range of generally toxic aromatic compounds.
Rohola Hosseini +5 more
doaj +1 more source
Conditional Protein Splicing Switch in Hyperthermophiles through an Intein-Extein Partnership
mBio, 2018 Inteins are intervening proteins that undergo an autocatalytic splicing reaction that ligates flanking host protein sequences termed exteins. Some intein-containing proteins have evolved to couple splicing to environmental signals; this represents a new ...
Christopher W. Lennon +3 more
doaj +1 more source