Results 1 to 10 of about 1,332 (116)

A Missing Link between Retrotransposons and Retroviruses

MBio, 2022
The origin and deep evolution of retroviruses remain largely unclear. It has been proposed that retroviruses might have originated from a Ty3/Gypsy retrotransposon, but all known Ty3/Gypsy retrotransposons are only distantly related to retroviruses ...
Guan-Zhu Han
exaly   +3 more sources

Inpactor, Integrated and Parallel Analyzer and Classifier of LTR Retrotransposons and Its Application for Pineapple LTR Retrotransposons Diversity and Dynamics

Biology, 2018
One particular class of Transposable Elements (TEs), called Long Terminal Repeats (LTRs), retrotransposons, comprises the most abundant mobile elements in plant genomes.
Simon Orozco Arias, Romain Guyot, Andrea Garavito   +2 more
exaly   +3 more sources

Cell Compartment-Specific Folding of Ty1 Long Terminal Repeat Retrotransposon RNA Genome

Viruses, 2022
The structural transitions RNAs undergo during trafficking are not well understood. Here, we used the well-developed yeast Ty1 retrotransposon to provide the first structural model of genome (g) RNA in the nucleus from a retrovirus-like transposon ...
Małgorzata Zawadzka, Angelika Andrzejewska-Romanowska, Julita Gumna, David J. Garfinkel, Katarzyna Pachulska-Wieczorek   +4 more
doaj   +1 more source

Retrotransposons and Telomeres

Biochemistry (Moscow), 2023
Abstract Transposable elements (TEs) comprise a significant part of eukaryotic genomes being a major source of genome instability and mutagenesis. Cellular defense systems suppress the TE expansion at all stages of their life cycle.
Alla I, Kalmykova, Olesya A, Sokolova
openaire   +2 more sources

Retrotransposons: How the continuous evolutionary front shapes plant genomes for response to heat stress

Frontiers in Plant Science, 2022
Long terminal repeat retrotransposons (LTR retrotransposons) are the most abundant group of mobile genetic elements in eukaryotic genomes and are essential in organizing genomic architecture and phenotypic variations.
Pradeep K. Papolu, Muthusamy Ramakrishnan, Muthusamy Ramakrishnan, Sileesh Mullasseri, Ruslan Kalendar, Ruslan Kalendar, Qiang Wei, Long−Hai Zou, Zishan Ahmad, Kunnummal Kurungara Vinod, Ping Yang, Ping Yang, Mingbing Zhou, Mingbing Zhou   +13 more
doaj   +1 more source

Stress Induced Activation of LTR Retrotransposons in the Drosophila melanogaster Genome

Life, 2023
Background: Retrotransposons with long terminal repeats (LTR retrotransposons) are widespread in all groups of eukaryotes and are often both the cause of new mutations and the source of new sequences.
Polina A. Milyaeva, Inna V. Kukushkina, Alexander I. Kim, Lidia N. Nefedova   +3 more
doaj   +1 more source

Genome-wide characterization of LTR retrotransposons in the non-model deep-sea annelid Lamellibrachia luymesi

BMC Genomics, 2021
Background Long Terminal Repeat retrotransposons (LTR retrotransposons) are mobile genetic elements composed of a few genes between terminal repeats and, in some cases, can comprise over half of a genome’s content.
Oluchi Aroh, Kenneth M. Halanych
doaj   +1 more source

Disruption of piRNA machinery by deletion of ASZ1/GASZ results in the expression of aberrant chimeric transcripts in gonocytes

The Journal of Reproduction and Development, 2022
In the male germline, the machinery to repress retrotransposons that threaten genomic integrity via the piRNA pathway is established in gonocytes. It has been reported that disruption of the piRNA pathway leads to activation of retrotransposons and ...
Shinya IKEDA, Koki TANAKA, Reiko OHTANI, Akifumi KANDA, Yusuke SOTOMARU, Tomohiro KONO, Yayoi OBATA   +6 more
doaj   +1 more source

Retrotransposons in pluripotent stem cells

Cell Regeneration, 2020
Transposable elements constitute about half of the mammalian genome, and can be divided into two classes: the class I (retrotransposons) and the class II (DNA transposons).
Jingwen Wang, Junjiu Huang, Guang Shi
doaj   +1 more source

Coordination of retrotransposons and type I interferon with distinct interferon pathways in dermatomyositis, systemic lupus erythematosus and autoimmune blistering disease

Scientific Reports, 2021
Type I interferon (IFN) plays a crucial role in innate and adaptive immunity, and aberrant IFN responses are involved in systemic autoimmune diseases, such as systemic lupus erythematosus (SLE) and dermatomyositis (DM).
Yuko Kuriyama, Akira Shimizu, Saki Kanai, Daisuke Oikawa, Sei-ichiro Motegi, Fuminori Tokunaga, Osamu Ishikawa   +6 more
doaj   +1 more source