Results 21 to 30 of about 1,385 (169)
BMC Genomics, 2010 Background Retrotransposons are transposable elements that proliferate within eukaryotic genomes through a process involving reverse transcription. The numbers of retrotransposons within genomes and differences between closely related species may yield ...
Willerslev Eske, Mourier Tobias
doaj +1 more source
Research progress of LINE-1 in the diagnosis, prognosis, and treatment of gynecologic tumors
Frontiers in Oncology, 2023 The retrotransposon known as long interspersed nuclear element-1 (LINE-1), which is currently the sole autonomously mobile transposon in the human genome, can result in insertional mutations, chromosomal rearrangements, and genomic instability. In recent
Jiaojiao Fu +19 more
doaj +1 more source
Retroviral-like determinants and functions required for dimerization of Ty1 retrotransposon RNA
RNA BiologyDuring replication of long terminal repeat (LTR)-retrotransposons, their proteins and genome (g) RNA assemble into virus-like particles (VLPs) that are not infectious but functionally related to retroviral virions. Both virions and VLPs contain gRNA in a
Julita Gumna +4 more
doaj +1 more source
Mobile DNA, 2019 Background Nesting is common in LTR retrotransposons, especially in large genomes containing a high number of elements. Results We analyzed 12 plant genomes and obtained 1491 pairs of nested and original (pre-existing) LTR retrotransposons.
Pavel Jedlicka +4 more
doaj +1 more source
BMC Genomics, 2010 Background Chromodomain-containing Gypsy LTR retrotransposons or chromoviruses are widely distributed among eukaryotes and have been found in plants, fungi and vertebrates.
Blinov Alexander +2 more
doaj +1 more source
Frontiers in Genetics, 2013 The molecular mechanisms of the transposition of non-long terminal repeat (non-LTR) retrotransposons are not well understood; the key questions of how the 3’-ends of cDNA copies integrate and how site-specific integration occurs remain unresolved ...
Dmitry V. Mukha +3 more
doaj +1 more source
Current Opinion in Genetics & Development, 1992 In the decade since Ty elements were discovered, advocates have argued they could be used as a genetic entrée to elusive host-type functions required by retroviruses. However, the advent of the polymerase chain reaction, coupled with a boom in funding for human immunodeficiency virus research have moved retroviral research apace, raising questions as ...
openaire +4 more sources
The DIRS1 Group of Retrotransposons [PDF]
Molecular Biology and Evolution, 2001 Only three retrotransposons of the DIRS1 group have previously been described: DIRS1 from the slime mold Dictyostelium discoideum, PAT from the nematode Panagrellus redivivus, and Prt1 from the zygomycetous fungus Phycomyces blakesleeanus. Analyses of the reverse transcriptase sequences encoded by these elements suggest that they are related to the ...
T J, Goodwin, R T, Poulter
openaire +2 more sources
RNA Editing and Retrotransposons in Neurology
Frontiers in Molecular Neuroscience, 2018 Compared to sites in protein-coding sequences many more targets undergoing adenosine to inosine (A-to-I) RNA editing were discovered in non-coding regions of human cerebral transcripts, particularly in genetic transposable elements called ...
Heinz Krestel +2 more
doaj +1 more source
TUT-TUTting retrotransposons [PDF]
Nature Reviews Molecular Cell Biology, 2018 3′uridylation by TUT4 and TUT7 is shown as a post-transcriptional mechanism restricting retrotransposition of LINE-1 elements and also replication of animal RNA viruses.
openaire +2 more sources