Results 21 to 30 of about 25,174 (246)

Retrotransposons and Telomeres

open access: yesBiochemistry (Moscow), 2023
Abstract Transposable elements (TEs) comprise a significant part of eukaryotic genomes being a major source of genome instability and mutagenesis. Cellular defense systems suppress the TE expansion at all stages of their life cycle.
Alla I, Kalmykova, Olesya A, Sokolova
openaire   +2 more sources

Stress Induced Activation of LTR Retrotransposons in the Drosophila melanogaster Genome

open access: yesLife, 2023
Background: Retrotransposons with long terminal repeats (LTR retrotransposons) are widespread in all groups of eukaryotes and are often both the cause of new mutations and the source of new sequences.
Polina A. Milyaeva   +3 more
doaj   +1 more source

Genome-wide characterization of LTR retrotransposons in the non-model deep-sea annelid Lamellibrachia luymesi

open access: yesBMC Genomics, 2021
Background Long Terminal Repeat retrotransposons (LTR retrotransposons) are mobile genetic elements composed of a few genes between terminal repeats and, in some cases, can comprise over half of a genome’s content.
Oluchi Aroh, Kenneth M. Halanych
doaj   +1 more source

Disruption of piRNA machinery by deletion of ASZ1/GASZ results in the expression of aberrant chimeric transcripts in gonocytes

open access: yesThe Journal of Reproduction and Development, 2022
In the male germline, the machinery to repress retrotransposons that threaten genomic integrity via the piRNA pathway is established in gonocytes. It has been reported that disruption of the piRNA pathway leads to activation of retrotransposons and ...
Shinya IKEDA   +6 more
doaj   +1 more source

Retrotransposons in pluripotent stem cells

open access: yesCell Regeneration, 2020
Transposable elements constitute about half of the mammalian genome, and can be divided into two classes: the class I (retrotransposons) and the class II (DNA transposons).
Jingwen Wang, Junjiu Huang, Guang Shi
doaj   +1 more source

Coordination of retrotransposons and type I interferon with distinct interferon pathways in dermatomyositis, systemic lupus erythematosus and autoimmune blistering disease

open access: yesScientific Reports, 2021
Type I interferon (IFN) plays a crucial role in innate and adaptive immunity, and aberrant IFN responses are involved in systemic autoimmune diseases, such as systemic lupus erythematosus (SLE) and dermatomyositis (DM).
Yuko Kuriyama   +6 more
doaj   +1 more source

Retrotransposons as pathogenicity factors of the plant pathogenic fungus Botrytis cinerea

open access: yesGenome Biology, 2021
Background Retrotransposons are genetic elements inducing mutations in all domains of life. Despite their detrimental effect, retrotransposons can become temporarily active during epigenetic reprogramming and cellular stress response, which may ...
Antoine Porquier   +8 more
doaj   +1 more source

LTR-retrotransposons in R. exoculata and other crustaceans [PDF]

open access: yes, 2013
Transposable elements are major constituents of eukaryote genomes and have a great impact on genome structure and stability. They can contribute to the genetic diversity and evolution of organisms. Knowledge of their distribution among several genomes is
Graça, Paula   +5 more
core   +1 more source

Retrotransposons [PDF]

open access: yesCurrent Biology, 2012
June 27, 1970 was a significant day for our understanding of both the flow of information in biological systems and the evolution of eukaryotic genomes as this was the day that Nature published back-to-back papers reporting the discovery of an enzyme that copies RNA into DNA. This soon became known as reverse transcriptase and the RNA tumour viruses in
openaire   +2 more sources

Diversity Chromosome Evolution of Ty1-copia Retrotransposons in Pennisetum purpureum Revealed by FISH

open access: yesAgronomy, 2022
Pennisetum purpureum is a potential species for biofuel production. Characterization and chromosomal distribution of retrotransposons could enhance the comprehension of the role and dynamics of the repetitive elements in plants.
Zehuai Yu   +4 more
doaj   +1 more source

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