Results 31 to 40 of about 27,166 (184)

Evolutionary genomics revealed interkingdom distribution of Tcn1-like chromodomain-containing Gypsy LTR retrotransposons among fungi and plants

BMC Genomics, 2010
Background Chromodomain-containing Gypsy LTR retrotransposons or chromoviruses are widely distributed among eukaryotes and have been found in plants, fungi and vertebrates.
Blinov Alexander, Smyshlyaev Georgiy, Novikova Olga   +2 more
doaj   +1 more source

Research progress of LINE-1 in the diagnosis, prognosis, and treatment of gynecologic tumors

Frontiers in Oncology, 2023
The retrotransposon known as long interspersed nuclear element-1 (LINE-1), which is currently the sole autonomously mobile transposon in the human genome, can result in insertional mutations, chromosomal rearrangements, and genomic instability. In recent
Jiaojiao Fu, Jiaojiao Fu, Tiansheng Qin, Tiansheng Qin, Tiansheng Qin, Tiansheng Qin, Chaoming Li, Jiaojiao Zhu, Jiaojiao Zhu, Yaoyao Ding, Yaoyao Ding, Meiying Zhou, Qing Yang, Qing Yang, Xiaofeng Liu, Xiaofeng Liu, Juanhong Zhou, Juanhong Zhou, Fan Chen, Fan Chen   +19 more
doaj   +1 more source

Endonuclease domain of the Drosophila melanogaster R2 non-LTR retrotransposon and related retroelements: a new model for transposition

Frontiers in Genetics, 2013
The molecular mechanisms of the transposition of non-long terminal repeat (non-LTR) retrotransposons are not well understood; the key questions of how the 3’-ends of cDNA copies integrate and how site-specific integration occurs remain unresolved ...
Dmitry V. Mukha, Elena G. Pasyukova, Tatiana V. Kapelinskaya, Arina S. Kagramanova   +3 more
doaj   +1 more source

Defending the genome from the enemy within:mechanisms of retrotransposon suppression in the mouse germline [PDF]

, 2013
The viability of any species requires that the genome is kept stable as it is transmitted from generation to generation by the germ cells. One of the challenges to transgenerational genome stability is the potential mutagenic activity of transposable ...
Richard R. Meehan, Dunican, Donncha S; id_orcid, Meehan, Richard, Ian R. Adams, Marie MacLennan, James H. Crichton, Crichton, James H, Maclennan, Marie, Adams, Ian R, Donncha S. Dunican   +9 more
core   +1 more source

Retrotransposons that maintain chromosome ends

, 2011
Reverse transcriptases have shaped genomes in many ways. A remarkable example of this shaping is found on telomeres of the genus Drosophila, where retrotransposons have a vital role in chromosome structure.
Mary-Lou Pardue, Pardue, Mary-Lou, P. G. DeBaryshe, DeBaryshe, P. G.   +3 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Determination of plant-specific retrotransposons in chicken

, 2022
Mobile genetic elements are also known as transposons, comprising a significant proportion of plant and animal genomes. Retrotransposons, a class of transposons, move copy and paste mechanism and, therefore, cause genome obesity.
Bilgi, Fatih, Marakli, Sevgi, Bulbul, Cihat Erdem, Mercan, Levent   +3 more
core   +1 more source

Characterization, Genomic Organization, Abundance, and Chromosomal Distribution of Ty1-copia Retrotransposons in Erianthus arundinaceus

Frontiers in Plant Science, 2017
Erianthus arundinaceus is an important wild species of the genus Saccharum with many valuable traits. However, the composition and structure of its genome are largely unknown, which have hindered its utilization in sugarcane breeding and evolutionary ...
Yongji Huang, Ling Luo, Xuguang Hu, Fan Yu, Yongqing Yang, Zuhu Deng, Zuhu Deng, Jiayun Wu, Jiayun Wu, Rukai Chen, Muqing Zhang   +10 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Retrotransposons Manipulating Mammalian Skeletal Development in Chondrocytes [PDF]

, 2020
Retrotransposons are genetic elements that copy and paste themselves in the host genome through transcription, reverse-transcription, and integration processes.
Ishikawa, Takanori, Kubota, Satoshi, Kawata, Kazumi, Nishida, Takashi, Hattori, Takako   +4 more
core   +2 more sources