Results 31 to 40 of about 25,174 (246)

Long interspersed element-1 (LINE-1): passenger or driver in human neoplasms? [PDF]

PLoS Genetics, 2013
LINE-1 (L1) retrotransposons make up a significant portion of human genomes, with an estimated 500,000 copies per genome. Like other retrotransposons, L1 retrotransposons propagate through RNA sequences that are reverse transcribed into DNA sequences ...
Nemanja Rodić, Kathleen H Burns
doaj   +1 more source

A whole genome analysis of long-terminal-repeat retrotransposon transcription in leaves of Populus trichocarpa L. subjected to different stresses

Caryologia, 2020
Long terminal repeat retrotransposons have a main role in shaping the structure of plant genomes. We used available genomic resources to study as several factors affect the expression of long terminal repeat retrotransposons in Populus trichocarpa.
Alberto Vangelisti, Gabriele Usai, Flavia Mascagni, Lucia Natali, Tommaso Giordani, Andrea Cavallini   +5 more
doaj   +1 more source

The Singular Evolution of Olea Genome Structure

Frontiers in Plant Science, 2022
The current view of plant genome evolution proposes that genome size has mainly been determined by polyploidisation and amplification/loss of transposons, with a minor role played by other repeated sequences, such as tandem repeats.
Flavia Mascagni, Elena Barghini, Marilena Ceccarelli, Luciana Baldoni, Carlos Trapero, Carlos Trapero, Concepción Muñoz Díez, Lucia Natali, Andrea Cavallini, Tommaso Giordani   +9 more
doaj   +1 more source

Retrotranspositions in orthologous regions of closely related grass species

BMC Evolutionary Biology, 2006
Background Retrotransposons are commonly occurring eukaryotic transposable elements (TEs). Among these, long terminal repeat (LTR) retrotransposons are the most abundant TEs and can comprise 50–90% of the genome in higher plants.
Swigoňová Zuzana, Du Chunguang, Messing Joachim   +2 more
doaj   +1 more source

Telomeric retrotransposons show propensity to form G-quadruplexes in various eukaryotic species

Mobile DNA, 2023
Background Canonical telomeres (telomerase-synthetised) are readily forming G-quadruplexes (G4) on the G-rich strand. However, there are examples of non-canonical telomeres among eukaryotes where telomeric tandem repeats are invaded by specific ...
Pavel Jedlička, Viktor Tokan, Iva Kejnovská, Roman Hobza, Eduard Kejnovský   +4 more
doaj   +1 more source

Comprehensive In Silico Analysis of Retrotransposon Insertions within the Survival Motor Neuron Genes Involved in Spinal Muscular Atrophy

Biology, 2022
Transposable elements (TEs) are interspersed repetitive and mobile DNA sequences within the genome. Better tools for evaluating TE-derived sequences have provided insights into the contribution of TEs to human development and disease.
Albano Pinto, Catarina Cunha, Raquel Chaves, Matthew E. R. Butchbach, Filomena Adega   +4 more
doaj   +1 more source

Large-scale transcriptome data reveals transcriptional activity of fission yeast LTR retrotransposons

BMC Genomics, 2010
Background Retrotransposons are transposable elements that proliferate within eukaryotic genomes through a process involving reverse transcription. The numbers of retrotransposons within genomes and differences between closely related species may yield ...
Willerslev Eske, Mourier Tobias
doaj   +1 more source

Research progress of LINE-1 in the diagnosis, prognosis, and treatment of gynecologic tumors

Frontiers in Oncology, 2023
The retrotransposon known as long interspersed nuclear element-1 (LINE-1), which is currently the sole autonomously mobile transposon in the human genome, can result in insertional mutations, chromosomal rearrangements, and genomic instability. In recent
Jiaojiao Fu, Jiaojiao Fu, Tiansheng Qin, Tiansheng Qin, Tiansheng Qin, Tiansheng Qin, Chaoming Li, Jiaojiao Zhu, Jiaojiao Zhu, Yaoyao Ding, Yaoyao Ding, Meiying Zhou, Qing Yang, Qing Yang, Xiaofeng Liu, Xiaofeng Liu, Juanhong Zhou, Juanhong Zhou, Fan Chen, Fan Chen   +19 more
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Retroviral-like determinants and functions required for dimerization of Ty1 retrotransposon RNA

RNA Biology
During replication of long terminal repeat (LTR)-retrotransposons, their proteins and genome (g) RNA assemble into virus-like particles (VLPs) that are not infectious but functionally related to retroviral virions. Both virions and VLPs contain gRNA in a
Julita Gumna, Katarzyna J. Purzycka, Hyo Won Ahn, David J. Garfinkel, Katarzyna Pachulska-Wieczorek   +4 more
doaj   +1 more source

Nested plant LTR retrotransposons target specific regions of other elements, while all LTR retrotransposons often target palindromes and nucleosome-occupied regions: in silico study

Mobile DNA, 2019
Background Nesting is common in LTR retrotransposons, especially in large genomes containing a high number of elements. Results We analyzed 12 plant genomes and obtained 1491 pairs of nested and original (pre-existing) LTR retrotransposons.
Pavel Jedlicka, Matej Lexa, Ivan Vanat, Roman Hobza, Eduard Kejnovsky   +4 more
doaj   +1 more source