Results 21 to 30 of about 29,245 (266)

The influence of anchoring of remote supports on the stability of mobile transport and technological machines equipped with boom lift manipulators [PDF]

Научно-технический вестник Брянского государственного университета, 2018
The article presents a mathematical model for calculating the characteristics of stability against overturning for mobile transport and technological machines equipped with boom lift manipulators. This model allows us to perform a quantitative assessment
Lagerev A.V., Lagerev I.A.
doaj   +1 more source

Cryo-EM structure of a licensed DNA replication origin

Nature Communications, 2017
Origins of replication are licensed by loading of MCM onto DNA, and origin firing depends on interaction with Cdc45 and GINS to form two CMG holo-helicases. Here, authors determine the cryo-EM structures of DNA-bound MCM and visualise a phospho-dependent
Ferdos Abid Ali, Max E. Douglas, Julia Locke, Valerie E. Pye, Andrea Nans, John F. X. Diffley, Alessandro Costa   +6 more
doaj   +1 more source

Operating Point Optimization of Agricultural Tractor–Implement Combinations as Constraint Optimization Problem

Eng
Increasing the process efficiency of agricultural tasks is a key measure to decrease overall costs and CO2 emissions. However, optimizing tractor–implement combinations is challenging due to the variety of processes and implements and the complexity of ...
Benjamin Kazenwadel, Marina Graf, Lukas Michiels, Marcus Geimer   +3 more
doaj   +1 more source

Automatic Estimation of Excavator’s Actual Productivity in Trenching and Grading Operations Using Building Information Modeling (BIM)

Actuators, 2023
This paper discusses the excavator’s actual productivity in trenching and grading operations. In these tasks, the quantity of material moved is not significant; precision within specified tolerances is the key focus.
Amirmasoud Molaei, Antti Kolu, Niko Haaraniemi, Marcus Geimer   +3 more
doaj   +1 more source

TECHNIQUE OF FUNCTIONAL UNIFICATION OF ADAPTIVE HYDRAULIC DRIVE MODULE CAPABLE OF LOAD STABILIZATION ON THE WORKING BODY OF MOBILE MACHINES

Advanced Engineering Research, 2018
Introduction. Issues on the functional unification of the adaptive hydraulic  drive  module  are  studied.  For  the  first  time,  self-adapting   mechanisms   are   considered   taking   into   account adaptive intercommunication of the load control ...
V. A. Pershin, T. A. Khinikadze
doaj   +1 more source

Mission profiles and energy management strategies for electric trucks with fuel cell range extenders

Transportation Engineering
In electric trucks equipped with fuel cell range extenders, energy management strategies are used to control and distribute the power demand between the battery pack and the fuel cell system.
Igor William Santos Leal Cruz, Lennart Buck, Timo Wyszynski, Marco Schramm, Ludger Frerichs   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source